Butterfield, D. Allan

Polyubiquitinylation Profile in Down Syndrome Brain Before and After the Development of Alzheimer Neuropathology

Tramutola, A., Di Domenico, F., Barone, E., Arena, A., Giorgi, A., di Francesco, L., Schininà, M. E., Coccia, R., Head, E., Butterfield, D. A., et al. (2017) · Antioxidants & Redox Signaling

Alzheimer's disease research and treatmentsUbiquitin and proteasome pathways

Cited by 49

Insulin resistance, oxidative stress and mitochondrial defects in Ts65dn mice brain: a harmful synergistic path in down syndrome

Lanzillotta, C., Tramutola, A., Di Giacomo, G., Marini, F., Butterfield, D. A., Di Domenico, F., Perluigi, M., & Barone, E. (2021) · Free Radical Biology and Medicine

Down syndrome and intellectual disability researchAlzheimer's disease research and treatments

Cited by 47

Protective effect of ferulic acid ethyl ester against oxidative stress mediated by UVB irradiation in human epidermal melanocytes

Di Domenico, F., Di Domenico, F., Perluigi, M., Foppoli, C., Blarzino, C., Coccia, R., De Marco, F., Butterfield, D. A., & Cini, C. (2009) · Free Radical Research

Skin Protection and Agingmelanin and skin pigmentation

Cited by 41

Proteomic identification of specifically carbonylated brain proteins in APPNLh/APPNLh×PS-1P264L/PS-1P264L human double mutant knock-in mice model of Alzheimer disease as a function of age

Sultana, R., Robinson, R. A. S., Di Domenico, F., Abdul, H. M., Clair, D. K. S., Markesbery, W. R., Cai, J., Pierce, W. M., & Butterfield, D. A. (2011) · Journal of Proteomics

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 41

Activation of p53 in Down Syndrome and in the Ts65Dn mouse brain is associated with a pro-apoptotic phenotype

Tramutola, A., Pupo, G., Di Domenico, F., Barone, E., Arena, A., Lanzillotta, C., Broekaart, D., Blarzino, C., Head, E., Butterfield, D. A., et al. (2016) · Journal of Alzheimer s Disease

Down syndrome and intellectual disability researchAlzheimer's disease research and treatments

Cited by 40

Aberrant crosstalk between insulin signaling and mTOR in young Down syndrome individuals revealed by neuronal‐derived extracellular vesicles

Perluigi, M., Picca, A., Montanari, E., Calvani, R., Marini, F., Matassa, R., Tramutola, A., Villani, A., Familiari, G., Domenico, F. D., et al. (2022) · Alzheimer's & Dementia

Down syndrome and intellectual disability researchExtracellular vesicles in disease

Cited by 35

Profiles of brain oxidative damage, ventricular alterations, and neurochemical metabolites in the striatum of PINK1 knockout rats as functions of age and gender: Relevance to Parkinson disease

Ren, X., Hinchie, A., Swomley, A., Powell, D. K., & Butterfield, D. A. (2019) · Free Radical Biology and Medicine

Parkinson's Disease Mechanisms and TreatmentsNuclear Receptors and Signaling

Cited by 29

Protein nitration profile of CD3+ lymphocytes from Alzheimer disease patients: Novel hints on immunosenescence and biomarker detection

Tramutola, A., Abate, G., Lanzillotta, C., Triani, F., Barone, E., Iavarone, F., Vincenzoni, F., Castagnola, M., Marziano, M., Memo, M., et al. (2018) · Free Radical Biology and Medicine

Alzheimer's disease research and treatmentsRedox biology and oxidative stress

Cited by 26

Lack of p53 Affects the Expression of Several Brain Mitochondrial Proteins: Insights from Proteomics into Important Pathways Regulated by p53

Fiorini, A., Sultana, R., Barone, E., Cenini, G., Perluigi, M., Mancuso, C., Cai, J., Klein, J. B., St. Clair, D., & Butterfield, D. A. (2012) · PLoS ONE

Mitochondrial Function and PathologyCancer-related Molecular Pathways

Cited by 16

Formation of a protein-bound pyrazinium free radical cation during glycation of histone H1

Wondrak, G. T., Varadarajan, S., Butterfield, D. A., & Jacobson, M. K. (2000) · Free Radical Biology and Medicine

Advanced Glycation End Products researchElectron Spin Resonance Studies

Cited by 16