Goncalves, Marcus D.

Rapamycin-Induced Insulin Resistance Is Mediated by mTORC2 Loss and Uncoupled from Longevity

Lamming, D. W., Ye, L., Katajisto, P., Goncalves, M. D., Saitoh, M., Stevens, D. M., Davis, J. G., Salmon, A. B., Richardson, A., Ahima, R. S., et al. (2012) · Science

PI3K/AKT/mTOR signaling in cancerMetabolism, Diabetes, and Cancer

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An atlas of substrate specificities for the human serine/threonine kinome

Johnson, J. L., Yaron, T. M., Huntsman, E. M., Kerelsky, A., Song, J., Regev, A., Lin, T.-Y., Liberatore, K., Cizin, D. M., Cohen, B. M., et al. (2023) · Nature

Advanced Proteomics Techniques and ApplicationsProtein Kinase Regulation and GTPase Signaling

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Suppression of insulin feedback enhances the efficacy of PI3K inhibitors

Hopkins, B. D., Pauli, C., Du, X., Wang, D. G., Li, X., Wu, D., Amadiume, S. C., Goncalves, M. D., Hodakoski, C., Lundquist, M. R., et al. (2018) · Nature

PI3K/AKT/mTOR signaling in cancerMetabolism, Diabetes, and Cancer

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High-fructose corn syrup enhances intestinal tumor growth in mice

Goncalves, M. D., Lu, C., Tutnauer, J., Hartman, T. E., Hwang, S.-K., Murphy, C. J., Pauli, C., Morris, R., Taylor, S., Bosch, K., et al. (2019) · Science

Diet, Metabolism, and DiseaseMetabolism, Diabetes, and Cancer

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Phosphatidylinositol 3-kinase, growth disorders, and cancer

Goncalves, M. D., Hopkins, B. D., & Cantley, L. C. (2018) · New England Journal of Medicine

PI3K/AKT/mTOR signaling in cancerMetabolism, Diabetes, and Cancer

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Dietary fructose improves intestinal cell survival and nutrient absorption

Taylor, S. R., Ramsamooj, S., Liang, R. J., Katti, A., Pozovskiy, R., Vasan, N., Hwang, S.-K., Nahiyaan, N., Francoeur, N. J., Schatoff, E. M., et al. (2021) · Nature

Diet, Metabolism, and DiseaseMetabolism, Diabetes, and Cancer

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Insulin–PI3K signalling: an evolutionarily insulated metabolic driver of cancer

Hopkins, B. D., Goncalves, M. D., & Cantley, L. C. (2020) · Nature Reviews Endocrinology

PI3K/AKT/mTOR signaling in cancerMetabolism, Diabetes, and Cancer

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The effects of a soluble activin type IIB receptor on obesity and insulin sensitivity

Akpan, I., Goncalves, M. D., Dhir, R., Yin, X., Pistilli, E. E., Bogdanovich, S., Khurana, T. S., Ucran, J., Lachey, J., & Ahima, R. S. (2009) · International Journal of Obesity

Adipokines, Inflammation, and Metabolic DiseasesMuscle Physiology and Disorders

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Akt deficiency attenuates muscle size and function but not the response to ActRIIB inhibition

Goncalves, M. D., Pistilli, E. E., Balduzzi, A., Birnbaum, M. J., Lachey, J., Khurana, T. S., & Ahima, R. S. (2010) · PLoS ONE

Muscle Physiology and DisordersMuscle metabolism and nutrition

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Management of phosphatidylinositol-3-kinase inhibitor-associated hyperglycemia

Goncalves, M. D., & Farooki, A. (2022) · Integrative Cancer Therapies

Metabolism, Diabetes, and CancerPI3K/AKT/mTOR signaling in cancer

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Managing hyperglycemia and rash associated with alpelisib: expert consensus recommendations using the Delphi technique

Gallagher, E. J., Moore, H., Lacouture, M. E., Dent, S. F., Farooki, A., Goncalves, M. D., Isaacs, C., Johnston, A., Juric, D., Quandt, Z., et al. (2024) · npj Breast Cancer

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