McReynolds, Melanie R.

Restoring metabolism of myeloid cells reverses cognitive decline in ageing

Minhas, P. S., Latif-Hernandez, A., McReynolds, M. R., Durairaj, A. S., Wang, Q., Rubin, A., Joshi, A. U., He, J. Q., Gauba, E., Liu, L., et al. (2021) · Nature

Neuroinflammation and Neurodegeneration MechanismsGenetics, Aging, and Longevity in Model Organisms

Cited by 526

CD38 ecto-enzyme in immune cells is induced during aging and regulates NAD+ and NMN levels

Chini, C. C. S., Peclat, T. R., Warner, G. M., Kashyap, S., Espindola-Netto, J. M., de Oliveira, G. C., Gomez, L. S., Hogan, K. A., Tarragó, M. G., Puranik, A. S., et al. (2020) · Nature Metabolism

Sirtuins and Resveratrol in MedicineBiochemical and Molecular Research

Cited by 349

SLC25A51 is a mammalian mitochondrial NAD(+) transporter

Luongo, T. S., Eller, J. M., Lu, M.-J., Niere, M., Raith, F., Perry, C., Bornstein, M. R., Oliphint, P., Wang, L., McReynolds, M. R., et al. (2020) · Nature

Mitochondrial Function and PathologySirtuins and Resveratrol in Medicine

Cited by 308

NAD precursors cycle between host tissues and the gut microbiome

Chellappa, K., McReynolds, M. R., Lu, W., Zeng, X., Makarov, M., Hayat, F., Mukherjee, S., Bhat, Y. R., Lingala, S. R., Shima, R. T., et al. (2022) · Cell Metabolism

Sirtuins and Resveratrol in MedicineGut microbiota and health

Cited by 146

NAD+ flux is maintained in aged mice despite lower tissue concentrations

McReynolds, M. R., Chellappa, K., Chiles, E., Jankowski, C., Shen, Y., Chen, L., Descamps, H. C., Mukherjee, S., Bhat, Y. R., Lingala, S. R., et al. (2021) · Cell Systems

Sirtuins and Resveratrol in MedicineBiochemical and Molecular Research

Cited by 112

Aged mice exhibit widespread metabolic changes but preserved major fluxes

Jankowski, C. S. R., Samarah, L. Z., MacArthur, M. R., Mitchell, S. J., Weilandt, D. R., Hunter, C. J., Zeng, X., McReynolds, M. R., & Rabinowitz, J. D. (2025) · Cell Metabolism

Metabolomics and Mass Spectrometry StudiesGenetics, Aging, and Longevity in Model Organisms

Cited by 19