Holcomb, Leigh A.

Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes

Holcomb, L., Gordon, M. N., McGowan, E., Yu, X., Benkovic, S., Jantzen, P., Wright, K., Saad, I., Mueller, R., Morgan, D., et al. (1998) · Nature Medicine

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 1,386

Behavioral changes in transgenic mice expressing both amyloid precursor protein and presenilin-1 mutations: lack of association with amyloid deposits

Holcomb, L. A., Gordon, M. N., Jantzen, P., Hsiao, K., Duff, K., & Morgan, D. (1999) · Behavior Genetics

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 353

Time Course of the Development of Alzheimer-like Pathology in the Doubly Transgenic PS1+APP Mouse

Gordon, M. N., Holcomb, L. A., Jantzen, P. T., DiCarlo, G., Wilcock, D., Boyett, K. W., Connor, K., Melachrino, J., O'Callaghan, J. P., & Morgan, D. (2002) · Experimental Neurology

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 247

Centella asiatica extract selectively decreases amyloid β levels in hippocampus of Alzheimer's disease animal model

Dhanasekaran, M., Holcomb, L. A., Hitt, A. R., Tharakan, B., Porter, J. W., Young, K. A., & Manyam, B. V. (2009) · Phytotherapy Research

Medicinal Plants and NeuroprotectionAlzheimer's disease research and treatments

Cited by 175

Elevated neuron number in the limbic thalamus in major depression

Young, K. A., Holcomb, L. A., Yazdani, U., Hicks, P. B., & German, D. C. (2004) · American Journal of Psychiatry

Treatment of Major DepressionStress Responses and Cortisol

Cited by 169

Bacopa monniera extract reduces amyloid levels in PSAPP mice

Holcomb, L. A., Dhanasekaran, M., Hitt, A. R., Young, K. A., Riggs, M., & Manyam, B. V. (2006) · Journal of Alzheimer's Disease

Alzheimer's disease research and treatmentsMedicinal Plants and Neuroprotection

Cited by 156

Neuroprotective mechanisms of ayurvedic antidementia botanical Bacopa monniera

Dhanasekaran, M., Tharakan, B., Holcomb, L. A., Hitt, A. R., Young, K. A., & Manyam, B. V. (2007) · Phytotherapy Research

Medicinal Plants and NeuroprotectionAlzheimer's disease research and treatments

Cited by 148