Kostka, Dennis

A high-resolution map of human evolutionary constraint using 29 mammals

Broad Institute Sequencing Platform and Whole Genome Assembly Team, Lindblad-Toh, K., Baylor College of Medicine Human Genome Sequencing Center Sequencing Team, Genome Institute at Washington University, Garber, M., Zuk, O., Lin, M. F., Parker, B. J., Washietl, S., Kheradpour, P., et al. (2011) · Nature

Genomics and Phylogenetic StudiesChromosomal and Genetic Variations

Cited by 1,108

Regulatory networks define phenotypic classes of human stem cell lines

Müller, F.-J., Laurent, L. C., Kostka, D., Ulitsky, I., Williams, R., Lu, C., Park, I.-H., Rao, M. S., Shamir, R., Schwartz, P. H., et al. (2008) · Nature

Pluripotent Stem Cells ResearchDevelopmental Biology and Gene Regulation

Cited by 343

scds: computational annotation of doublets in single-cell RNA sequencing data

Bais, A. S., & Kostka, D. (2020) · Bioinformatics

Single-cell and spatial transcriptomicsGene expression and cancer classification

Cited by 308

Finding disease specific alterations in the co-expression of genes

Kostka, D., & Spang, R. (2004) · Bioinformatics

Gene expression and cancer classificationBioinformatics and Genomic Networks

Cited by 148

The role of GC-biased gene conversion in shaping the fastest evolving regions of the human genome

Kostka, D., Hubisz, M. J., Siepel, A., & Pollard, K. S. (2012) · Molecular Biology and Evolution

Evolution and Genetic DynamicsGenomics and Phylogenetic Studies

Cited by 102

A model-based analysis of GC-biased gene conversion in the human and chimpanzee genomes

Capra, J. A., Hubisz, M. J., Kostka, D., Pollard, K. S., & Siepel, A. (2013) · PLoS Genetics

Evolution and Genetic DynamicsChromosomal and Genetic Variations

Cited by 77

Random forest based similarity learning for single cell RNA sequencing data

Pouyan, M. B., & Kostka, D. (2018) · Bioinformatics

Single-cell and spatial transcriptomicsGene expression and cancer classification

Cited by 50

Developmental loci harbor clusters of accelerated regions that evolved independently in ape lineages

Kostka, D., Holloway, A. K., & Pollard, K. S. (2018) · Molecular Biology and Evolution

Chromosomal and Genetic VariationsGenomics and Phylogenetic Studies

Cited by 32