Vahedi, Golnaz

Epigenetic stability of exhausted T cells limits durability of reinvigoration by PD-1 blockade

Pauken, K. E., Sammons, M. A., Odorizzi, P. M., Manne, S., Godec, J., Khan, O., Drake, A. M., Chen, Z., Sen, D. R., Kurachi, M., et al. (2016) · Science

Cancer Immunotherapy and BiomarkersT-cell and B-cell Immunology

Cited by 1,348

TCF-1-centered transcriptional network drives an effector versus exhausted CD8 T cell-fate decision

Chen, Z., Ji, Z., Ngiow, S. F., Manne, S., Cai, Z., Huang, A. C., Johnson, J., Staupe, R. P., Bengsch, B., Xu, C., et al. (2019) · Immunity

T-cell and B-cell ImmunologyCancer Immunotherapy and Biomarkers

Cited by 709

Opposing regulation of the locus encoding IL-17 through direct, reciprocal actions of STAT3 and STAT5

Yang, X.-P., Ghoreschi, K., Steward-Tharp, S. M., Rodriguez-Canales, J., Zhu, J., Grainger, J. R., Hirahara, K., Sun, H.-W., Wei, L., Vahedi, G., et al. (2011) · Nature Immunology

Psoriasis: Treatment and PathogenesisT-cell and B-cell Immunology

Cited by 583

Transcriptional and Epigenetic Control of T Helper Cell Specification: Molecular Mechanisms Underlying Commitment and Plasticity

Kanno, Y., Vahedi, G., Hirahara, K., Singleton, K., & O'Shea, J. J. (2012) · Annual Review of Immunology

T-cell and B-cell ImmunologyGenomics and Chromatin Dynamics

Cited by 342

Genomic views of STAT function in CD4+ T helper cell differentiation

O'Shea, J. J., Lahesmaa, R., Vahedi, G., Laurence, A., & Kanno, Y. (2011) · Nature Reviews Immunology

Cytokine Signaling Pathways and InteractionsT-cell and B-cell Immunology

Cited by 295

Lineage-Determining Transcription Factor TCF-1 Initiates the Epigenetic Identity of T Cells

Johnson, J. L., Georgakilas, G., Petrovic, J., Kurachi, M., Cai, S., Harly, C., Pear, W. S., Bhandoola, A., Wherry, E. J., & Vahedi, G. (2018) · Immunity

Genomics and Chromatin DynamicsT-cell and B-cell Immunology

Cited by 226

Interleukin-23-Induced Transcription Factor Blimp-1 Promotes Pathogenicity of T Helper 17 Cells

Jain, R., Chen, Y., Kanno, Y., Joyce-Shaikh, B., Vahedi, G., Hirahara, K., Blumenschein, W. M., Sukumar, S., Haines, C. J., Sadekova, S., et al. (2016) · Immunity

Psoriasis: Treatment and PathogenesisT-cell and B-cell Immunology

Cited by 167

A mouse model of HIES reveals pro- and anti-inflammatory functions of STAT3

Steward-Tharp, S. M., Laurence, A., Kanno, Y., Kotlyar, A., Villarino, A. V., Sciume, G., Kuchen, S., Resch, W., Wohlfert, E. A., Jiang, K., et al. (2014) · Blood

Immunodeficiency and Autoimmune DisordersCytokine Signaling Pathways and Interactions

Cited by 87