Kay, Thomas W.

SOCS1 Is a Critical Inhibitor of Interferon γ Signaling and Prevents the Potentially Fatal Neonatal Actions of this Cytokine

Alexander, W. S., Starr, R., Fenner, J. E., Scott, C. L., Handman, E., Sprigg, N. S., Corbin, J. E., Cornish, A. L., Darwiche, R., Owczarek, C. M., et al. (1999) · Cell

Cytokine Signaling Pathways and Interactionsinterferon and immune responses

Cited by 762

Demonstration of islet-autoreactive CD8 T cells in insulitic lesions from recent onset and long-term type 1 diabetes patients

Coppieters, K. T., Dotta, F., Amirian, N., Campbell, P. D., Kay, T. W. H., Atkinson, M. A., Roep, B. O., & von Herrath, M. G. (2012) · Journal of Experimental Medicine

Diabetes and associated disordersT-cell and B-cell Immunology

Cited by 672

Granulocyte Macrophage Colony-Stimulating Factor

McQualter, J. L., Darwiche, R., Ewing, C., Onuki, M., Kay, T. W., Hamilton, J. A., Reid, H. H., & Bernard, C. C. A. (2001) · The Journal of Experimental Medicine

Multiple Sclerosis Research StudiesT-cell and B-cell Immunology

Cited by 477

Evidence-Informed Clinical Practice Recommendations for Treatment of Type 1 Diabetes Complicated by Problematic Hypoglycemia

Choudhary, P., Rickels, M. R., Senior, P. A., Vantyghem, M.-C., Maffi, P., Kay, T. W., Keymeulen, B., Inagaki, N., Saudek, F., Lehmann, R., et al. (2015) · Diabetes Care

Diabetes Management and ResearchDiabetes Management and Education

Cited by 233

Hypoxia-inducible factor-1α regulates β cell function in mouse and human islets

Cheng, K., Ho, K., Stokes, R., Scott, C., Lau, S. M., Hawthorne, W. J., O’Connell, P. J., Loudovaris, T., Kay, T. W., Kulkarni, R. N., et al. (2010) · Journal of Clinical Investigation

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 230

Baricitinib and β-cell function in patients with new-onset type 1 diabetes

Waibel, M., Wentworth, J. M., So, M., Couper, J. J., Cameron, F. J., MacIsaac, R. J., Atlas, G., Gorelik, A., Litwak, S., Sanz-Villanueva, L., et al. (2023) · New England Journal of Medicine

Diabetes and associated disordersDiabetes Management and Research

Cited by 194

Glucocorticoids target suppressor of cytokine signaling 1 (SOCS1) and type 1 interferons to regulate Toll-like receptor-induced STAT1 activation

Bhattacharyya, S., Zhao, Y., Kay, T. W. H., & Muglia, L. J. (2011) · Proceedings of the National Academy of Sciences

Cytokine Signaling Pathways and InteractionsImmune Response and Inflammation

Cited by 93

Macrophage deletion of SOCS1 increases sensitivity to LPS and palmitic acid and results in systemic inflammation and hepatic insulin resistance

Sachithanandan, N., Graham, K. L., Galic, S., Honeyman, J. E., Fynch, S. L., Hewitt, K. A., Steinberg, G. R., & Kay, T. W. (2011) · Diabetes

Adipokines, Inflammation, and Metabolic DiseasesCytokine Signaling Pathways and Interactions

Cited by 81

Association between primary graft function and 5-year outcomes of islet allogeneic transplantation in type 1 diabetes: a retrospective, multicentre, observational cohort study in 1210 patients from the Collaborative Islet Transplant Registry

Chetboun, M., Drumez, E., Ballou, C., Maanaoui, M., Payne, E., Barton, F., Kerr-Conte, J., Vantyghem, M.-C., Piemonti, L., Rickels, M. R., et al. (2023) · The Lancet Diabetes & Endocrinology

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 64

The future of type 1 diabetes therapy

Ziegler, A.-G., Cengiz, E., & Kay, T. W. H. (2025) · The Lancet

Diabetes and associated disordersDiabetes Management and Research

Cited by 42

Case Report: Hypoglycemia Due to a Novel Activating Glucokinase Variant in an Adult – a Molecular Approach

Koneshamoorthy, A., Seniveratne-Epa, D., Calder, G., Sawyer, M., Kay, T. W. H., Farrell, S., Loudovaris, T., Mariana, L., McCarthy, D., Lyu, R., et al. (2022) · Frontiers in Endocrinology

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 11