Decker, Michael W.

Behavioral profile of P2X7 receptor knockout mice in animal models of depression and anxiety: Relevance for neuropsychiatric disorders

Basso, A. M., Bratcher, N. A., Harris, R. R., Jarvis, M. F., Decker, M. W., & Rueter, L. E. (2009) · Behavioural Brain Research

Tryptophan and brain disordersAdenosine and Purinergic Signaling

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(S)-3-methyl-5-(1-methyl-2-pyrrolidinyl) isoxazole (ABT 418): A novel cholinergic ligand with cognition-enhancing and anxiolytic activities: II. In vivo characterization

Decker, M. W., Brioni, J. D., Sullivan, J. P., Buckley, M. J., Radek, R. J., Raszkiewicz, J. L., Kang, C. H., Kim, D. J., Giardina, W. J., & Wasicak, J. T. (1994) · The Journal of Pharmacology and Experimental Therapeutics

Nicotinic Acetylcholine Receptors StudyNeuroscience and Neuropharmacology Research

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Neuronal nicotinic receptor agonists for the treatment of attention-deficit/hyperactivity disorder: Focus on cognition

Wilens, T. E., & Decker, M. W. (2007) · Biochemical Pharmacology

Attention Deficit Hyperactivity DisorderNicotinic Acetylcholine Receptors Study

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Prefrontal β2 Subunit-Containing and α7 Nicotinic Acetylcholine Receptors Differentially Control Glutamatergic and Cholinergic Signaling

Parikh, V., Ji, J., Decker, M. W., & Sarter, M. (2010) · The Journal of Neuroscience

Nicotinic Acetylcholine Receptors StudyNeuroscience and Neuropharmacology Research

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Enhancement of sustained attention performance by the nicotinic acetylcholine receptor agonist ABT-418 in intact but not basal forebrain-lesioned rats

McGaughy, J., Decker, M. W., & Sarter, M. (1999) · Psychopharmacology

Nicotinic Acetylcholine Receptors StudyCholinesterase and Neurodegenerative Diseases

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Glutamatergic Contributions to Nicotinic Acetylcholine Receptor Agonist-Evoked Cholinergic Transients in the Prefrontal Cortex

Parikh, V., Man, K., Decker, M. W., & Sarter, M. (2008) · The Journal of Neuroscience

Nicotinic Acetylcholine Receptors StudyNeuroscience and Neuropharmacology Research

Cited by 127

Highly Selective Butyrylcholinesterase Inhibitors With Tunable Duration of Action by Chemical Modification of Transferable Carbamate Units Exhibit Pronounced Neuroprotective Effect in an Alzheimer’s Disease Mouse Model

Hoffmann, M., Stiller, C., Endres, E., Scheiner, M., Gunesch, S., Sotriffer, C., Maurice, T., & Decker, M. (2019) · Journal of Medicinal Chemistry

Cholinesterase and Neurodegenerative DiseasesAlzheimer's disease research and treatments

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In Vivo Pharmacological Characterization of a Novel Selective α7 Neuronal Nicotinic Acetylcholine Receptor Agonist ABT-107: Preclinical Considerations in Alzheimer's Disease

Bitner, R. S., Bunnelle, W. H., Decker, M. W., Drescher, K. U., Kohlhaas, K. L., Markosyan, S., Marsh, K. C., Nikkel, A. L., Browman, K., Radek, R., et al. (2010) · The Journal of Pharmacology and Experimental Therapeutics

Nicotinic Acetylcholine Receptors StudyAlzheimer's disease research and treatments

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ABT-089 [2-methyl-3-(2-(S)-pyrrolidinylmethoxy)pyridine dihydrochloride]: II. A novel cholinergic channel modulator with effects on cognitive performance in rats and monkeys

Decker, M. W., Bannon, A. W., Curzon, P., Gunther, K. L., Brioni, J. D., Holladay, M. W., Lin, N.-H., Li, Y., Daanen, J. F., Buccafusco, J. J., et al. (1997) · The Journal of Pharmacology and Experimental Therapeutics

Nicotinic Acetylcholine Receptors StudyCholinesterase and Neurodegenerative Diseases

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Anxiolytic-like effects of the novel cholinergic channel activator ABT-418

Brioni, J. D., O'Neill, A. B., Kim, D. J., Buckley, M. J., Decker, M. W., & Arneric, S. P. (1994) · The Journal of Pharmacology and Experimental Therapeutics

Nicotinic Acetylcholine Receptors StudyNeuroscience and Neuropharmacology Research

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ABT-089: pharmacological properties of a neuronal nicotinic acetylcholine receptor agonist for the potential treatment of cognitive disorders

Rueter, L. E., Anderson, D. J., Briggs, C. A., Donnelly‐Roberts, D. L., Gintant, G. A., Gopalakrishnan, M., Lin, N., Osinski, M. A., Reinhart, G. A., Buckley, M. J., et al. (2004) · CNS Drug Reviews

Nicotinic Acetylcholine Receptors StudyNeuroscience and Neuropharmacology Research

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Structure−Activity Studies on 2-Methyl-3-(2(S)-pyrrolidinylmethoxy)pyridine (ABT-089): An Orally Bioavailable 3-Pyridyl Ether Nicotinic Acetylcholine Receptor Ligand with Cognition-Enhancing Properties

Lin, N.-H., Gunn, D. E., Ryther, K. B., Garvey, D. S., Donnelly-Roberts, D. L., Decker, M. W., Brioni, J. D., Buckley, M. J., Rodrigues, A. D., Marsh, K. G., et al. (1997) · Journal of Medicinal Chemistry

Nicotinic Acetylcholine Receptors StudyCholinesterase and Neurodegenerative Diseases

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Structure–Activity Relationships and Computational Investigations into the Development of Potent and Balanced Dual-Acting Butyrylcholinesterase Inhibitors and Human Cannabinoid Receptor 2 Ligands with Pro-Cognitive in Vivo Profiles

Dolles, D., Hoffmann, M., Gunesch, S., Marinelli, O., Möller, J., Santoni, G., Chatonnet, A., Lohse, M. J., Wittmann, H.-J., Strasser, A., et al. (2018) · Journal of Medicinal Chemistry

Cholinesterase and Neurodegenerative DiseasesCannabis and Cannabinoid Research

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Melatonin- and Ferulic Acid-Based HDAC6 Selective Inhibitors Exhibit Pronounced Immunomodulatory Effects In Vitro and Neuroprotective Effects in a Pharmacological Alzheimer’s Disease Mouse Model

He, F., Chou, C. J., Scheiner, M., Poeta, E., Yuan Chen, N., Gunesch, S., Hoffmann, M., Sotriffer, C., Monti, B., Maurice, T., et al. (2021) · Journal of Medicinal Chemistry

Histone Deacetylase Inhibitors ResearchCholinesterase and Neurodegenerative Diseases

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Dual-Acting Cholinesterase–Human Cannabinoid Receptor 2 Ligands Show Pronounced Neuroprotection in Vitro and Overadditive and Disease-Modifying Neuroprotective Effects in Vivo

Scheiner, M., Dolles, D., Gunesch, S., Hoffmann, M., Nabissi, M., Marinelli, O., Naldi, M., Bartolini, M., Petralla, S., Poeta, E., et al. (2019) · Journal of Medicinal Chemistry

Cholinesterase and Neurodegenerative DiseasesAlzheimer's disease research and treatments

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In-vitro stability and metabolism of a tacrine–silibinin codrug

Zenger, K., Chen, X., Decker, M., & Kraus, B. (2013) · Journal of Pharmacy and Pharmacology

Silymarin and Mushroom PoisoningPharmacogenetics and Drug Metabolism

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