Hamdy, Freddie C.

The repertoire of mutational signatures in human cancer

Alexandrov, L. B., Kim, J., Haradhvala, N. J., Huang, M. N., Tian Ng, A. W., Wu, Y., Boot, A., Covington, K. R., Gordenin, D. A., Bergstrom, E. N., et al. (2020) · Nature

Cancer Genomics and DiagnosticsChromatin Remodeling and Cancer

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Pan-cancer analysis of whole genomes

The ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium, Aaltonen, L. A., Abascal, F., Abeshouse, A., Aburatani, H., Adams, D. J., Agrawal, N., Ahn, K. S., Ahn, S.-M., Aikata, H., et al. (2020) · Nature

Cancer Genomics and DiagnosticsChromatin Remodeling and Cancer

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The evolutionary history of 2,658 cancers

Gerstung, M., Jolly, C., Leshchiner, I., Dentro, S. C., Gonzalez, S., Rosebrock, D., Mitchell, T. J., Rubanova, Y., Anur, P., Yu, K., et al. (2020) · Nature

Cancer Genomics and DiagnosticsChromatin Remodeling and Cancer

Cited by 1,057

Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci

Study, T. P., Schumacher, F. R., (APCB), A. P. C. B., Study, T. I., Canary PASS Investigators, Breast and Prostate Cancer Cohort Consortium (BPC3), The PRACTICAL (Prostate Cancer Association Group to Investigate Cancer-Associated Alterations in the Genome) Consortium, (CAPS), C. O. T. P. I. S., Prostate Cancer Genome-wide Association Study of Uncommon Susceptibility Loci (PEGASUS), The Genetic Associations and Mechanisms in Oncology (GAME-ON)/Elucidating Loci Involved in Prostate Cancer Susceptibility (ELLIPSE) Consortium, et al. (2018) · Nature Genetics

Genetic Associations and EpidemiologyProstate Cancer Treatment and Research

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Patterns of somatic structural variation in human cancer genomes

Li, Y., Roberts, N. D., Wala, J. A., Shapira, O., Schumacher, S. E., Kumar, K., Khurana, E., Waszak, S., Korbel, J. O., Haber, J. E., et al. (2020) · Nature

Cancer Genomics and DiagnosticsGenomic variations and chromosomal abnormalities

Cited by 867

Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing

Cortés-Ciriano, I., Lee, J. J.-K., Xi, R., Jain, D., Jung, Y. L., Yang, L., Gordenin, D., Klimczak, L. J., Zhang, C.-Z., Pellman, D. S., et al. (2020) · Nature Genetics

Cancer Genomics and DiagnosticsGenomic variations and chromosomal abnormalities

Cited by 712

Quality improvement report Improving design and conduct of randomised trials by embedding them in qualitative research: ProtecT (prostate testing for cancer and treatment) study Commentary: presenting unbiased information to patients can be difficult

Donovan, J., Little, P., Mills, N., Smith, M., Brindle, L., Jacoby, A., Peters, T., Frankel, S., Neal, D., & Hamdy, F. (2002) · BMJ

Ethics in Clinical ResearchStatistical Methods in Clinical Trials

Cited by 533

Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition

Rodriguez-Martin, B., Alvarez, E. G., Baez-Ortega, A., Zamora, J., Supek, F., Demeulemeester, J., Santamarina, M., Ju, Y. S., Temes, J., Garcia-Souto, D., et al. (2020) · Nature Genetics

Genomic variations and chromosomal abnormalitiesCancer Genomics and Diagnostics

Cited by 451

Disruption of chromatin folding domains by somatic genomic rearrangements in human cancer

Akdemir, K. C., Le, V. T., Chandran, S., Li, Y., Verhaak, R. G., Beroukhim, R., Campbell, P. J., Chin, L., Dixon, J. R., Futreal, P. A., et al. (2020) · Nature Genetics

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 283

Mutational signatures of ionizing radiation in second malignancies

Behjati, S., Gundem, G., Wedge, D. C., Roberts, N. D., Tarpey, P. S., Cooke, S. L., Van Loo, P., Alexandrov, L. B., Ramakrishna, M., Davies, H., et al. (2016) · Nature Communications

Cancer Genomics and DiagnosticsDNA Repair Mechanisms

Cited by 274

Understanding and improving recruitment to randomised controlled trials: qualitative research approaches

Elliott, D., Husbands, S., Hamdy, F. C., Holmberg, L., & Donovan, J. L. (2017) · European Urology

Ethics in Clinical ResearchHealth Policy Implementation Science

Cited by 161

BMP-regulated exosomes from Drosophila male reproductive glands reprogram female behavior

Corrigan, L., Redhai, S., Leiblich, A., Fan, S.-J., Perera, S. M. W., Patel, R., Gandy, C., Wainwright, S. M., Morris, J. F., Hamdy, F., et al. (2014) · Journal of Cell Biology

Extracellular vesicles in diseaseCellular transport and secretion

Cited by 155

Perceptions of equipoise are crucial to trial participation: a qualitative study of men in the ProtecT study

Mills, N., Donovan, J. L., Smith, M., Jacoby, A., Neal, D. E., & Hamdy, F. C. (2003) · Controlled Clinical Trials

Ethics in Clinical ResearchStatistical Methods in Clinical Trials

Cited by 142

Glutamine deprivation alters the origin and function of cancer cell exosomes

Fan, S., Kroeger, B., Marie, P. P., Bridges, E. M., Mason, J. D., McCormick, K., Zois, C. E., Sheldon, H., Khalid Alham, N., Johnson, E., et al. (2020) · The EMBO Journal

Extracellular vesicles in diseaseCellular transport and secretion

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Considerations and methods for placebo controls in surgical trials (ASPIRE guidelines)

Beard, D. J., Campbell, M. K., Blazeby, J. M., Carr, A. J., Weijer, C., Cuthbertson, B. H., Buchbinder, R., Pinkney, T., Bishop, F. L., Pugh, J., et al. (2020) · The Lancet

Statistical Methods in Clinical TrialsPain Management and Placebo Effect

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A recurrent truncating germline mutation in the BRIP1/FANCJ gene and susceptibility to prostate cancer

The UKGPCS Collaborators, T. B. A. O. U. S. S. O. O., Kote-Jarai, Z., Jugurnauth, S., Mulholland, S., Leongamornlert, D. A., Guy, M., Edwards, S., Tymrakiewitcz, M., O'Brien, L., Hall, A., et al. (2009) · British Journal of Cancer

BRCA gene mutations in cancerGenetic factors in colorectal cancer

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Atlas of prostate cancer heritability in European and African-American men pinpoints tissue-specific regulation

Gusev, A., Shi, H., Kichaev, G., Pomerantz, M., Li, F., Long, H. W., Ingles, S. A., Kittles, R. A., Strom, S. S., Rybicki, B. A., et al. (2016) · Nature Communications

Genetic Associations and EpidemiologyProstate Cancer Treatment and Research

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