Zigman, Jeffrey M.

Expression of ghrelin receptor mRNA in the rat and the mouse brain

Zigman, J. M., Jones, J. E., Lee, C. E., Saper, C. B., & Elmquist, J. K. (2006) · The Journal of Comparative Neurology

Regulation of Appetite and ObesityHypothalamic control of reproductive hormones

Cited by 1,074

Ghrelin

Müller, T. D., Nogueiras, R., Andermann, M. L., Andrews, Z. B., Anker, S. D., Argente, J., Batterham, R. L., Benoit, S. C., Bowers, C. Y., Broglio, F., et al. (2015) · Molecular Metabolism

Regulation of Appetite and ObesityGrowth Hormone and Insulin-like Growth Factors

Cited by 1,034

Leptin directly activates SF1 neurons in the VMH, and this action by leptin is required for normal body-weight homeostasis

Dhillon, H., Zigman, J. M., Ye, C., Lee, C. E., McGovern, R. A., Tang, V., Kenny, C. D., Christiansen, L. M., White, R. D., Edelstein, E. A., et al. (2006) · Neuron

Regulation of Appetite and ObesityHypothalamic control of reproductive hormones

Cited by 791

The orexigenic hormone ghrelin defends against depressive symptoms of chronic stress

Lutter, M., Sakata, I., Osborne-Lawrence, S., Rovinsky, S. A., Anderson, J. G., Jung, S., Birnbaum, S., Yanagisawa, M., Elmquist, J. K., Nestler, E. J., et al. (2008) · Nature Neuroscience

Regulation of Appetite and ObesityNeuropeptides and Animal Physiology

Cited by 644

Synaptic glutamate release by ventromedial hypothalamic neurons is part of the neurocircuitry that prevents hypoglycemia

Tong, Q., Ye, C., McCrimmon, R. J., Dhillon, H., Choi, B., Kramer, M. D., Yu, J., Yang, Z., Christiansen, L. M., Lee, C. E., et al. (2007) · Cell Metabolism

Regulation of Appetite and ObesityPancreatic function and diabetes

Cited by 413

Direct Insulin and Leptin Action on Pro-opiomelanocortin Neurons Is Required for Normal Glucose Homeostasis and Fertility

Hill, J. W., Elias, C. F., Fukuda, M., Williams, K. W., Berglund, E. D., Holland, W. L., Cho, Y.-R., Chuang, J.-C., Xu, Y., Choi, M., et al. (2010) · Cell Metabolism

Regulation of Appetite and ObesityHypothalamic control of reproductive hormones

Cited by 391

Characterization of Kiss1 neurons using transgenic mouse models

Cravo, R. M., Margatho, L. O., Osborne-Lawrence, S., Donato, J., Atkin, S., Bookout, A. L., Rovinsky, S., Frazão, R., Lee, C. E., Gautron, L., et al. (2011) · Neuroscience

Hypothalamic control of reproductive hormonesRegulation of Appetite and Obesity

Cited by 353

Ghrelin promotes and protects nigrostriatal dopamine function via a UCP2-dependent mitochondrial mechanism

Andrews, Z. B., Erion, D., Beiler, R., Liu, Z.-W., Abizaid, A., Zigman, J., Elsworth, J. D., Savitt, J. M., DiMarchi, R., Tschöp, M., et al. (2009) · The Journal of Neuroscience

Parkinson's Disease Mechanisms and TreatmentsRegulation of Appetite and Obesity

Cited by 289

The P7C3 class of neuroprotective compounds exerts antidepressant efficacy in mice by increasing hippocampal neurogenesis

Walker, A. K., Rivera, P. D., Wang, Q., Chuang, J.-C., Tran, S., Osborne-Lawrence, S., Estill, S. J., Starwalt, R., Huntington, P., Morlock, L., et al. (2015) · Molecular Psychiatry

Neurogenesis and neuroplasticity mechanismsTreatment of Major Depression

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Ghrelin Directly Stimulates Glucagon Secretion from Pancreatic α-Cells

Chuang, J.-C., Sakata, I., Kohno, D., Perello, M., Osborne-Lawrence, S., Repa, J. J., & Zigman, J. M. (2011) · Molecular Endocrinology

Pancreatic function and diabetesRegulation of Appetite and Obesity

Cited by 141

Chronic social defeat stress disrupts regulation of lipid synthesis

Chuang, J.-C., Cui, H., Mason, B. L., Mahgoub, M., Bookout, A. L., Yu, H. G., Perello, M., Elmquist, J. K., Repa, J. J., Zigman, J. M., et al. (2010) · Journal of Lipid Research

Lipid metabolism and biosynthesisLipid metabolism and disorders

Cited by 126

Central Nervous System Regulation of Energy Metabolism: Ghrelin versus Leptin

Nogueiras, R., Tschöp, M. H., & Zigman, J. M. (2008) · Annals of the New York Academy of Sciences

Regulation of Appetite and ObesityHypothalamic control of reproductive hormones

Cited by 115

A β3-Adrenergic-Leptin-Melanocortin Circuit Regulates Behavioral and Metabolic Changes Induced by Chronic Stress

Chuang, J.-C., Krishnan, V., Yu, H. G., Mason, B., Cui, H., Wilkinson, M. B., Zigman, J. M., Elmquist, J. K., Nestler, E. J., & Lutter, M. (2010) · Biological Psychiatry

Regulation of Appetite and ObesityStress Responses and Cortisol

Cited by 114

Disrupted hippocampal growth hormone secretagogue receptor 1α interaction with dopamine receptor D1 plays a role in Alzheimer′s disease

Tian, J., Guo, L., Sui, S., Driskill, C., Phensy, A., Wang, Q., Gauba, E., Zigman, J. M., Swerdlow, R. H., Kroener, S., et al. (2019) · Science Translational Medicine

Alzheimer's disease research and treatmentsNeuroscience and Neuropharmacology Research

Cited by 72

Liver-expressed antimicrobial peptide 2 elevation contributes to age-associated cognitive decline

Tian, J., Guo, L., Wang, T., Jia, K., Swerdlow, R. H., Zigman, J. M., & Du, H. (2023) · JCI Insight

Regulation of Appetite and ObesityDementia and Cognitive Impairment Research

Cited by 16