Leonard, Warren J.

A Critical Role for IL-21 in Regulating Immunoglobulin Production

Ozaki, K., Spolski, R., Feng, C. G., Qi, C.-F., Cheng, J., Sher, A., Morse, H. C., Liu, C., Schwartzberg, P. L., & Leonard, W. J. (2002) · Science

T-cell and B-cell ImmunologyImmunodeficiency and Autoimmune Disorders

Cited by 978

The role of shared receptor motifs and common Stat proteins in the generation of cytokine pleiotropy and redundancy by IL-2, IL-4, IL-7, IL-13, and IL-15

Lin, J.-X., Migone, T.-S., Tseng, M., Friedmann, M., Weatherbee, J. A., Zhou, L., Yamauchi, A., Bloom, E. T., Mietz, J., John, S., et al. (1995) · Immunity

Cytokine Signaling Pathways and InteractionsT-cell and B-cell Immunology

Cited by 752

Regulation of B Cell Differentiation and Plasma Cell Generation by IL-21, a Novel Inducer of Blimp-1 and Bcl-6

Ozaki, K., Spolski, R., Ettinger, R., Kim, H.-P., Wang, G., Qi, C.-F., Hwu, P., Shaffer, D. J., Akilesh, S., Roopenian, D. C., et al. (2004) · The Journal of Immunology

T-cell and B-cell ImmunologySystemic Lupus Erythematosus Research

Cited by 668

Modulation of transcription factor NF-kappa B binding activity by oxidation-reduction in vitro.

Toledano, M. B., & Leonard, W. J. (1991) · Proceedings of the National Academy of Sciences

NF-κB Signaling PathwaysRedox biology and oxidative stress

Cited by 657

Proliferating Transitory T Cells with an Effector-like Transcriptional Signature Emerge from PD-1+ Stem-like CD8+ T Cells during Chronic Infection

Hudson, W. H., Gensheimer, J., Hashimoto, M., Wieland, A., Valanparambil, R. M., Li, P., Lin, J.-X., Konieczny, B. T., Im, S. J., Freeman, G. J., et al. (2019) · Immunity

T-cell and B-cell ImmunologyCancer Immunotherapy and Biomarkers

Cited by 656

Biology and regulation of IL-2: from molecular mechanisms to human therapy

Spolski, R., Li, P., & Leonard, W. J. (2018) · Nature Reviews Immunology

T-cell and B-cell ImmunologyCytokine Signaling Pathways and Interactions

Cited by 637

The Jak-STAT pathway

Imada, K., & Leonard, W. J. (2000) · Molecular Immunology

Cytokine Signaling Pathways and InteractionsNF-κB Signaling Pathways

Cited by 610

Constitutively activated Jak-STAT pathway in T cells transformed with HTLV-I

Migone, T.-S., Lin, J.-X., Cereseto, A., Mulloy, J. C., O'Shea, J. J., Franchini, G., & Leonard, W. J. (1995) · Science

T-cell and Retrovirus StudiesCytokine Signaling Pathways and Interactions

Cited by 557

Modulation of cytokine receptors by IL-2 broadly regulates differentiation into helper T cell lineages

Liao, W., Lin, J.-X., Wang, L., Li, P., & Leonard, W. J. (2011) · Nature Immunology

T-cell and B-cell ImmunologyPsoriasis: Treatment and Pathogenesis

Cited by 474

Role of thymic stromal lymphopoietin in allergy and beyond

Ebina-Shibuya, R., & Leonard, W. J. (2023) · Nature Reviews Immunology

IL-33, ST2, and ILC PathwaysAsthma and respiratory diseases

Cited by 289

IL-21 Signaling in immunity

Leonard, W. J., & Wan, C.-K. (2016) · F1000Research

Cytokine Signaling Pathways and InteractionsT-cell and B-cell Immunology

Cited by 184

Recent advances in understanding the role of IL-4 signaling

Keegan, A. D., Leonard, W. J., & Zhu, J. (2021) · Faculty Reviews

Cytokine Signaling Pathways and InteractionsT-cell and B-cell Immunology

Cited by 154

Interleukin 21: a cytokine/cytokine receptor system that has come of age

Leonard, W. J., Zeng, R., & Spolski, R. (2008) · Journal of Leukocyte Biology

Cytokine Signaling Pathways and InteractionsT-cell and B-cell Immunology

Cited by 122

Transcription Factors IRF8 and PU.1 Are Required for Follicular B Cell Development and BCL6‐driven Germinal Center Responses

Wang, H., Jain, S., Li, P., Lin, J.-X., Oh, J., Qi, C., Gao, Y., Sun, J., Sakai, T., Naghashfar, Z., et al. (2019) · Proceedings of the National Academy of Sciences

T-cell and B-cell ImmunologyGenomics and Chromatin Dynamics

Cited by 81

Cloning, characterization, expression, and chromosomal localization of a human ferritin heavy-chain gene

Hentze, M. W., Keim, S., Papadopoulos, P., O'Brien, S., Modi, W., Drysdale, J., Leonard, W. J., Harford, J. B., & Klausner, R. D. (1986) · Proceedings of the National Academy of Sciences

Iron Metabolism and DisordersNeurological diseases and metabolism

Cited by 79

Cytokine signaling: Inhibitors keep cytokines in check

Kovanen, P. E., & Leonard, W. J. (1999) · Current Biology

Cytokine Signaling Pathways and InteractionsProtein Tyrosine Phosphatases

Cited by 49

Distinct tumorigenic potential of abl and raf in B cell neoplasia: abl activates the IL-6 signaling pathway

Hilbert, D. M., Migone, T.-S., Kopf, M., Leonard, W. J., & Rudikoff, S. (1996) · Immunity

Cytokine Signaling Pathways and InteractionsLymphoma Diagnosis and Treatment

Cited by 40

Importance of low affinity Elf-1 sites in the regulation of lymphoid-specific inducible gene expression.

John, S., Marais, R., Child, R., Light, Y., & Leonard, W. J. (1996) · The Journal of experimental medicine

Genomics and Chromatin DynamicsCytokine Signaling Pathways and Interactions

Cited by 35