Biology and regulation of IL-2: from molecular mechanisms to human therapy

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Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus

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IL-2: The First Effective Immunotherapy for Human Cancer

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Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus

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FOXP3 Controls Regulatory T Cell Function through Cooperation with NFAT

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A Validated Regulatory Network for Th17 Cell Specification

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Follicular regulatory T cells expressing Foxp3 and Bcl-6 suppress germinal center reactions

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Interleukin-2 at the Crossroads of Effector Responses, Tolerance, and Immunotherapy

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CRISPR-Based Technologies for the Manipulation of Eukaryotic Genomes

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CTCF-Mediated Human 3D Genome Architecture Reveals Chromatin Topology for Transcription

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Utilization of the beta and gamma chains of the IL‐2 receptor by the novel cytokine IL‐15.

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A Critical Role for IL-21 in Regulating Immunoglobulin Production

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MATURE T LYMPHOCYTE APOPTOSIS—Immune Regulation in a Dynamic and Unpredictable Antigenic Environment

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An essential role for the IL-2 receptor in Treg cell function

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Mutations of Jak-3 gene in patients with autosomal severe combined immune deficiency (SCID)

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Deregulated T Cell Activation and Autoimmunity in Mice Lacking Interleukin-2 Receptor β

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TH17 cells contribute to uveitis and scleritis and are expanded by IL-2 and inhibited by IL-27/STAT1

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Interleukin-2 Receptor Signaling: At the Interface between Tolerance and Immunity

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Cloning of the γ Chain of the Human IL-2 Receptor

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Mutation of Jak3 in a Patient with SCID: Essential Role of Jak3 in Lymphoid Development

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CD4 Regulatory T Cells Prevent Lethal Autoimmunity in IL-2Rβ-Deficient Mice

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Regulatory T-Cell Responses to Low-Dose Interleukin-2 in HCV-Induced Vasculitis

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Central Role of Defective Interleukin-2 Production in the Triggering of Islet Autoimmune Destruction

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Low-dose interleukin-2 treatment selectively modulates CD4+ T cell subsets in patients with systemic lupus erythematosus

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Interleukin-2 Inhibits Germinal Center Formation by Limiting T Follicular Helper Cell Differentiation

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In vivo expansion of T reg cells with IL-2–mAb complexes: induction of resistance to EAE and long-term acceptance of islet allografts without immunosuppression

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Epigenetic control of CD8+ T cell differentiation

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Modulation of cytokine receptors by IL-2 broadly regulates differentiation into helper T cell lineages

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IL-2 reverses established type 1 diabetes in NOD mice by a local effect on pancreatic regulatory T cells

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Fc-Optimized Anti-CD25 Depletes Tumor-Infiltrating Regulatory T Cells and Synergizes with PD-1 Blockade to Eradicate Established Tumors

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Cytokines and immunodeficiency diseases: critical roles of the γc‐dependent cytokines interleukins 2, 4, 7, 9, 15, and 21, and their signaling pathways

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Structural Biology of Shared Cytokine Receptors

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Human immune disorder arising from mutation of the α chain of the interleukin-2 receptor

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Therapeutic use of IL-2 to enhance antiviral T-cell responses in vivo

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Stat5 Activation Plays a Critical Role in Th2 Differentiation

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Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes

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Both integrated and differential regulation of components of the IL-2/IL-2 receptor system

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Immune homeostasis enforced by co-localized effector and regulatory T cells

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