Hetz, Claudio

Molecular mechanisms of cell death: recommendations of the nomenclature committee on cell death 2018.

Galluzzi, L., Vitale, I., Aaronson, S. A., Abrams, J. M., Adam, D., Agostinis, P., Alnemri, E. S., Altucci, L., Amelio, I., Andrews, D. W., et al. (2018) · Cell Death & Differentiation

Cell death mechanisms and regulationAutophagy in Disease and Therapy

Cited by 6,680

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).

Klionsky, D. J., Abdelmohsen, K., Abe, A., Abedin, M. J., Abeliovich, H., Acevedo Arozena, A., Adachi, H., Adams, C. M., Adams, P. D., Adeli, K., et al. (2016) · Autophagy

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

Cited by 5,894

Guidelines for the use and interpretation of assays for monitoring autophagy

Klionsky, D. J., Abdalla, F. C., Abeliovich, H., Abraham, R. T., Acevedo-Arozena, A., Adeli, K., Agholme, L., Agnello, M., Agostinis, P., Aguirre-Ghiso, J. A., et al. (2012) · Autophagy

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

Cited by 3,996

Mechanisms, regulation and functions of the unfolded protein response

Hetz, C., Zhang, K., & Kaufman, R. J. (2020) · Nature Reviews Molecular Cell Biology

Endoplasmic Reticulum Stress and DiseaseHeat shock proteins research

Cited by 2,666

Cyclophilin D is a component of mitochondrial permeability transition and mediates neuronal cell death after focal cerebral ischemia

Schinzel, A. C., Takeuchi, O., Huang, Z., Fisher, J. K., Zhou, Z., Rubens, J., Hetz, C., Danial, N. N., Moskowitz, M. A., & Korsmeyer, S. J. (2005) · Proceedings of the National Academy of Sciences

Mitochondrial Function and PathologyCell death mechanisms and regulation

Cited by 820

Endoplasmic reticulum stress and unfolded protein response in cardiovascular diseases

Ren, J., Bi, Y., Sowers, J. R., Hetz, C., & Zhang, Y. (2021) · Nature Reviews Cardiology

Endoplasmic Reticulum Stress and DiseaseHeat shock proteins research

Cited by 708

Disturbance of endoplasmic reticulum proteostasis in neurodegenerative diseases

Hetz, C., & Mollereau, B. (2014) · Nature Reviews Neuroscience

Endoplasmic Reticulum Stress and DiseaseHeat shock proteins research

Cited by 684

XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagy

Hetz, C., Thielen, P., Matus, S., Nassif, M., Court, F., Kiffin, R., Martinez, G., Cuervo, A. M., Brown, R. H., & Glimcher, L. H. (2009) · Genes & Development

Amyotrophic Lateral Sclerosis ResearchEndoplasmic Reticulum Stress and Disease

Cited by 530

BCL-2 family: integrating stress responses at the ER to control cell demise

Pihán, P., Carreras-Sureda, A., & Hetz, C. (2017) · Cell Death & Differentiation

Cell death mechanisms and regulationEndoplasmic Reticulum Stress and Disease

Cited by 274

Emerging roles of ER stress in the etiology and pathogenesis of Alzheimer's disease

Gerakis, Y., & Hetz, C. (2018) · The FEBS Journal

Endoplasmic Reticulum Stress and DiseaseAlzheimer's disease research and treatments

Cited by 226

Bax channel inhibitors prevent mitochondrion-mediated apoptosis and protect neurons in a model of global brain ischemia

Hetz, C., Vitte, P.-A., Bombrun, A., Rostovtseva, T. K., Montessuit, S., Hiver, A., Schwarz, M. K., Church, D. J., Korsmeyer, S. J., Martinou, J.-C., et al. (2005) · Journal of Biological Chemistry

Cell death mechanisms and regulationMitochondrial Function and Pathology

Cited by 176

Regulation of Memory Formation by the Transcription Factor XBP1

Martínez, G., Vidal, R. L., Mardones, P., Serrano, F. G., Ardiles, A. O., Wirth, C., Valdés, P., Thielen, P., Schneider, B. L., Kerr, B., et al. (2016) · Cell Reports

Memory and Neural MechanismsEndoplasmic Reticulum Stress and Disease

Cited by 163

Autophagy in hepatic adaptation to stress

Hazari, Y., Bravo-San Pedro, J. M., Hetz, C., Galluzzi, L., & Kroemer, G. (2020) · Journal of Hepatology

Autophagy in Disease and TherapyLiver physiology and pathology

Cited by 151

Measurement of autophagy flux in the nervous system in vivo

Castillo, K., Valenzuela, V, Matus, S., Nassif, M., Oñate, M., Fuentealba, Y., Encina, G., Irrazabal, T., Parsons, G., Court, F. A., et al. (2013) · Cell Death & Disease

Autophagy in Disease and TherapyAlzheimer's disease research and treatments

Cited by 127

Pathogenic role of BECN1/Beclin 1 in the development of amyotrophic lateral sclerosis

Nassif, M., Valenzuela, V., Rojas-Rivera, D., Vidal, R., Matus, S., Castillo, K., Fuentealba, Y., Kroemer, G., Levine, B., & Hetz, C. (2014) · Autophagy

Amyotrophic Lateral Sclerosis ResearchAutophagy in Disease and Therapy

Cited by 100

Targeting the unfolded protein response for disease intervention.

Rivas, A., Vidal, R. L., & Hetz, C. (2015) · Expert Opinion on Therapeutic Targets

Endoplasmic Reticulum Stress and DiseaseHeat shock proteins research

Cited by 62

Amyotrophic lateral sclerosis pathogenesis: a journey through the secretory pathway

Nassif, M., Matus, S., Castillo, K., & Hetz, C. (2010) · Antioxidants & Redox Signaling

Amyotrophic Lateral Sclerosis ResearchEndoplasmic Reticulum Stress and Disease

Cited by 60

A new method to measure autophagy flux in the nervous system

Matus, S., Valenzuela, V., & Hetz, C. (2014) · Autophagy

Autophagy in Disease and TherapyCellular transport and secretion

Cited by 29