Huso, David L.

A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses

Wu, S., Rhee, K.-J., Albesiano, E., Rabizadeh, S., Wu, X., Yen, H.-R., Huso, D. L., Brancati, F. L., Wick, E., McAllister, F., et al. (2009) · Nature Medicine

Gut microbiota and healthT-cell and B-cell Immunology

Cited by 1,812

Losartan, an AT1 Antagonist, Prevents Aortic Aneurysm in a Mouse Model of Marfan Syndrome

Habashi, J. P., Judge, D. P., Holm, T. M., Cohn, R. D., Loeys, B. L., Cooper, T. K., Myers, L., Klein, E. C., Liu, G., Calvi, C., et al. (2006) · Science

Connective tissue disorders researchAortic aneurysm repair treatments

Cited by 1,794

Patients with familial adenomatous polyposis harbor colonic biofilms containing tumorigenic bacteria

Dejea, C. M., Fathi, P., Craig, J. M., Boleij, A., Taddese, R., Geis, A. L., Wu, X., DeStefano Shields, C. E., Hechenbleikner, E. M., Huso, D. L., et al. (2018) · Science

Gut microbiota and healthBacterial biofilms and quorum sensing

Cited by 1,105

Mutant PIK3CA promotes cell growth and invasion of human cancer cells.

Samuels, Y., Diaz, L. A., Schmidt-Kittler, O., Cummins, J. M., DeLong, L., Cheong, I., Rago, C., Huso, D. L., Lengauer, C., Kinzler, K. W., et al. (2005) · Cancer Cell

PI3K/AKT/mTOR signaling in cancerProtein Kinase Regulation and GTPase Signaling

Cited by 915

Polyamine catabolism contributes to enterotoxigenic Bacteroides fragilis -induced colon tumorigenesis

Goodwin, A. C., Shields, C. E. D., Wu, S., Huso, D. L., Wu, X., Murray-Stewart, T. R., Hacker-Prietz, A., Rabizadeh, S., Woster, P. M., Sears, C. L., et al. (2011) · Proceedings of the National Academy of Sciences

Polyamine Metabolism and ApplicationsBacterial Cancer Therapy

Cited by 612

Nitric oxide synthase in cardiac sarcoplasmic reticulum

Xu, K. Y., Huso, D. L., Dawson, T. M., Bredt, D. S., & Becker, L. C. (1999) · Proceedings of the National Academy of Sciences

Nitric Oxide and Endothelin EffectsCardiac electrophysiology and arrhythmias

Cited by 480

Intratumoral injection of Clostridium novyi -NT spores induces antitumor responses

Roberts, N. J., Zhang, L., Janku, F., Collins, A., Bai, R.-Y., Staedtke, V., Rusk, A. W., Tung, D., Miller, M., Roix, J., et al. (2014) · Science Translational Medicine

Bacterial Cancer TherapyClostridium difficile and Clostridium perfringens research

Cited by 400

Short Telomeres, even in the Presence of Telomerase, Limit Tissue Renewal Capacity

Hao, L.-Y., Armanios, M., Strong, M. A., Karim, B., Feldser, D. M., Huso, D., & Greider, C. W. (2005) · Cell

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 302

Endothelial Arginase II: A Novel Target for the Treatment of Atherosclerosis

Ryoo, S., Gupta, G., Benjo, A., Lim, H. K., Camara, A., Sikka, G., Lim, H. K., Sohi, J., Santhanam, L., Soucy, K., et al. (2008) · Circulation Research

Nitric Oxide and Endothelin EffectsCardiovascular Health and Disease Prevention

Cited by 236

Integrin-modulating therapy prevents fibrosis and autoimmunity in mouse models of scleroderma

Gerber, E. E., Gallo, E. M., Fontana, S. C., Davis, E. C., Wigley, F. M., Huso, D. L., & Dietz, H. C. (2013) · Nature

Systemic Sclerosis and Related DiseasesConnective tissue disorders research

Cited by 190

Redundant Innate and Adaptive Sources of IL17 Production Drive Colon Tumorigenesis

Housseau, F., Wu, S., Wick, E. C., Fan, H., Wu, X., Llosa, N. J., Smith, K. N., Tam, A., Ganguly, S., Wanyiri, J. W., et al. (2016) · Cancer Research

T-cell and B-cell ImmunologyPsoriasis: Treatment and Pathogenesis

Cited by 143

Specific ablation of Stat3β distorts the pattern of Stat3-responsive gene expression and impairs recovery from endotoxic shock

Yoo, J.-Y., Huso, D. L., Nathans, D., & Desiderio, S. (2002) · Cell

Cytokine Signaling Pathways and InteractionsNF-κB Signaling Pathways

Cited by 139

Measurement and Characterization of Superoxide Generation in Microglial Cells: Evidence for an NADPH Oxidase-Dependent Pathway

Sankarapandi, S., Zweier, J. L., Mukherjee, G., Quinn, M. T., & Huso, D. L. (1998) · Archives of Biochemistry and Biophysics

Neutrophil, Myeloperoxidase and Oxidative MechanismsRedox biology and oxidative stress

Cited by 136

HMGA1 drives stem cell, inflammatory pathway, and cell cycle progression genes during lymphoid tumorigenesis

Schuldenfrei, A., Belton, A., Kowalski, J., Talbot, C. C., Di Cello, F., Poh, W., Tsai, H.-L., Shah, S. N., Huso, T. H., Huso, D. L., et al. (2011) · BMC Genomics

Genomics and Chromatin DynamicsLymphoma Diagnosis and Treatment

Cited by 85

A nephron-based model of the kidneys for macro-to-micro α-particle dosimetry

Hobbs, R. F., Song, H., Huso, D. L., H Sundel, M., & Sgouros, G. (2012) · Physics in Medicine and Biology

Radiopharmaceutical Chemistry and ApplicationsAdvanced Radiotherapy Techniques

Cited by 61

Telomere fusion to chromosome breaks reduces oncogenic translocations and tumour formation

Qi, L., Strong, M. A., Karim, B. O., Huso, D. L., & Greider, C. W. (2005) · Nature Cell Biology

Telomeres, Telomerase, and SenescenceDNA Repair Mechanisms

Cited by 32

Pharmacological and Toxicological Evaluation of 2-Fluoro-3-(2(S)-azetidinylmethoxy)pyridine (2-F-A-85380), a Ligand for Imaging Cerebral Nicotinic Acetylcholine Receptors with Positron Emission Tomography

Vaupel, D. B., Tella, S. R., Huso, D. L., Wagner, V. O., Mukhin, A. G., Chefer, S. I., Horti, A. G., London, E. D., Koren, A. O., & Kimes, A. S. (2005) · The Journal of Pharmacology and Experimental Therapeutics

Nicotinic Acetylcholine Receptors StudyRadiopharmaceutical Chemistry and Applications

Cited by 28