Telomere fusion to chromosome breaks reduces oncogenic translocations and tumour formation

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Telomere dysfunction and evolution of intestinal carcinoma in mice and humans

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Telomere dysfunction and Atm deficiency compromises organ homeostasis and accelerates ageing

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TEL1, an S. cerevisiae homolog of the human gene mutated in ataxia telangiectasia, is functionally related to the yeast checkpoint gene, MEC1

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Short Dysfunctional Telomeres Impair Tumorigenesis in the INK4aΔ2/3 Cancer-Prone Mouse

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The role of DNA breaks in genomic instability and tumorigenesis

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Telomerase-deficient mice with short telomeres are resistant to skin tumorigenesis

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Telomere dysfunction and the initiation of genome instability

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Telomerase and ATM/Tel1p Protect Telomeres from Nonhomologous End Joining

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Abnormal rearrangement within the α/δ T-cell receptor locus in lymphomas from Atm-deficient mice

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A Quantitative Assay for Telomere Protection in Saccharomyces cerevisiae

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Shortened telomeres join to DNA breaks interfering with their correct repair

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Short telomeres and ataxia-telangiectasia mutated deficiency cooperatively increase telomere dysfunction and suppress tumorigenesis.

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Telomeres in cancer: tumour suppression and genome instability

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Chromosomally unstable mouse tumours have genomic alterations similar to diverse human cancers

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Short Telomeres Limit Tumor Progression In Vivo by Inducing Senescence

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Telomeres, interstitial telomeric repeat sequences, and chromosomal aberrations

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Telomere dysfunction, genome instability and cancer

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Telomere Shortening and Alzheimer’s Disease

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Telomere instability and cancer

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Short telomeres in aggressive non-Hodgkin's lymphoma as a risk factor in lymphomagenesis

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Telomere dysfunction and genome instability

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Regulation of Senescence in Cancer and Aging

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<i>Ink4a</i> / <i>Arf</i> tumor suppressor does not modulate the degenerative conditions or tumor spectrum of the telomerase-deficient mouse

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Cooperation between p53 and the telomere-protecting shelterin component Pot1a in endometrial carcinogenesis

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Ku protein as a potential human T-cell leukemia virus type 1 (HTLV-1) Tax target in clastogenic chromosomal instability of mammalian cells

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Telomeres, telomerase, and cancer: mechanisms, biomarkers, and therapeutics

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Ataxia telangiectasia mutated (Atm) is not required for telomerase-mediated elongation of short telomeres

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Spectral karyotyping of human, mouse, rat and ape chromosomes – applications for genetic diagnostics and research

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Telomerase deficiency and telomere dysfunction inhibit mammary tumors induced by polyomavirus middle T oncogene

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Telomeres and DNA double-strand breaks: ever the twain shall meet?

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Overexpression of eIF-5A2 in mice causes accelerated organismal aging by increasing chromosome instability

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PARP1 and DNA-PKcs synergize to suppress p53 mutation and telomere fusions during T-lineage lymphomagenesis

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ATM-dependent DNA damage response constrains cell growth and drives clonal hematopoiesis in telomere biology disorders

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Multiple Mechanisms Contribute To Telomere Maintenance.

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Unstabilized DNA breaks in HTLV-1 Tax expressing cells correlate with functional targeting of Ku80, not PKcs, XRCC4, or H2AX

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Cibler les télomères pour forcer les cellules cancéreuses à rentrer en sénescence

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Using mice to unveil the genetics of cancer resistance

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Cancer, Senescence, and Aging: Translation from Basic Research to Clinics

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Fusing breaks

Hutchinson, E. (2005) · Nature reviews. Cancer · doi:10.1038/nrc1677

Comprimento telomérico no sistema nervoso central de um modelo de doença de Alzheimer tratado com lítio

Cardillo, G. D. M. (2018) · doi:10.11606/d.5.2018.tde-05062018-112209

Papers of Note

(2005) · Science of Aging Knowledge Environment · doi:10.1126/sageke.2005.25.nw24

Faculty Opinions recommendation of Telomeres in cancer: tumour suppression and genome instability.

Savage, S. A. (2018) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.727224887.793545187

Fusing breaks

Hutchinson, E. (2005) · Nature reviews. Cancer · doi:10.1038/nrc1677

Short telomeres and ataxia-telangiectasia mutated deficiency cooperatively increase telomere dysfunction and suppress tumorigenesis.

Qi, L., Strong, M. A., Karim, B. O., Armanios, M. Y., Huso, D. L., & Greider, C. W. (2003) · PubMed · Cited by 68 · see citing works

Short Telomeres and Ataxia-Telangiectasia Mutated Deficiency Cooperatively

(2016)

Abstract B64: Telomeric DNA sequence determines the mechanism of dysfunctional telomere fusion in human cancer cells

Stohr, B. A., Xu, L., & Blackburn, E. H. (2009) · Cancer Research · doi:10.1158/0008-5472.fbcr09-b64

The nature of telomere fusion and a definition of the critical telomere length in human cells

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