Visvader, Jane E.

Genome-wide association study identifies novel breast cancer susceptibility loci

Easton, D. F., Pooley, K. A., Dunning, A. M., Pharoah, P. D. P., Thompson, D., Ballinger, D. G., Struewing, J. P., Morrison, J., Field, H., Luben, R., et al. (2007) · Nature

Genetic Associations and EpidemiologyBRCA gene mutations in cancer

Cited by 2,319

Generation of a functional mammary gland from a single stem cell

Shackleton, M., Vaillant, F., Simpson, K. J., Stingl, J., Smyth, G. K., Asselin-Labat, M.-L., Wu, L., Lindeman, G. J., & Visvader, J. E. (2006) · Nature

Cancer Cells and MetastasisMesenchymal stem cell research

Cited by 2,005

Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers

kConFab, Lim, E., Vaillant, F., Wu, D., Forrest, N. C., Pal, B., Hart, A. H., Asselin-Labat, M.-L., Gyorki, D. E., Ward, T., et al. (2009) · Nature Medicine

BRCA gene mutations in cancerCancer Cells and Metastasis

Cited by 1,492

Gata-3 is an essential regulator of mammary-gland morphogenesis and luminal-cell differentiation

Asselin-Labat, M.-L., Sutherland, K. D., Barker, H., Thomas, R., Shackleton, M., Forrest, N. C., Hartley, L., Robb, L., Grosveld, F. G., van der Wees, J., et al. (2007) · Nature Cell Biology

Cancer Cells and MetastasisDevelopmental Biology and Gene Regulation

Cited by 840

FOG, a Multitype Zinc Finger Protein, Acts as a Cofactor for Transcription Factor GATA-1 in Erythroid and Megakaryocytic Differentiation

Tsang, A. P., Visvader, J. E., Turner, C. A., Fujiwara, Y., Yu, C., Weiss, M. J., Crossley, M., & Orkin, S. H. (1997) · Cell

Genomics and Chromatin DynamicsHemoglobinopathies and Related Disorders

Cited by 712

Control of mammary stem cell function by steroid hormone signalling

Asselin-Labat, M.-L., Vaillant, F., Sheridan, J. M., Pal, B., Wu, D., Simpson, E. R., Yasuda, H., Smyth, G. K., Martin, T. J., Lindeman, G. J., et al. (2010) · Nature

Estrogen and related hormone effectsCancer Cells and Metastasis

Cited by 693

ROAST: rotation gene set tests for complex microarray experiments

Wu, D., Lim, E., Vaillant, F., Asselin-Labat, M.-L., Visvader, J. E., & Smyth, G. K. (2010) · Bioinformatics

Bioinformatics and Genomic NetworksGene expression and cancer classification

Cited by 560

Transcriptome analyses of mouse and human mammary cell subpopulations reveal multiple conserved genes and pathways

Lim, E., Wu, D., Pal, B., Bouras, T., Asselin-Labat, M.-L., Vaillant, F., Yagita, H., Lindeman, G. J., Smyth, G. K., & Visvader, J. E. (2010) · Breast Cancer Research

Cancer Cells and MetastasisBreast Cancer Treatment Studies

Cited by 440

Differential hypermethylation of SOCS genes in ovarian and breast carcinomas

Sutherland, K. D., Lindeman, G. J., Choong, D. Y. H., Wittlin, S., Brentzell, L., Phillips, W., Campbell, I. G., & Visvader, J. E. (2004) · Oncogene

Epigenetics and DNA MethylationCytokine Signaling Pathways and Interactions

Cited by 217

GATA‐1 but not SCL induces megakaryocytic differentiation in an early myeloid line.

Visvader, J. E., Elefanty, A. G., Strasser, A., & Adams, J. M. (1992) · The EMBO Journal

Platelet Disorders and TreatmentsHematopoietic Stem Cell Transplantation

Cited by 189

The C-Terminal Zinc Finger of GATA-1 or GATA-2 Is Sufficient To Induce Megakaryocytic Differentiation of an Early Myeloid Cell Line

Visvader, J. E., Crossley, M., Hill, J., Orkin, S. H., & Adams, J. M. (1995) · Molecular and Cellular Biology

Platelet Disorders and TreatmentsGenomics and Chromatin Dynamics

Cited by 151

Tissue-specific designs of stem cell hierarchies

Visvader, J. E., & Clevers, H. (2016) · Nature Cell Biology

Cancer Cells and MetastasisDevelopmental Biology and Gene Regulation

Cited by 150

A phase Ib dose-escalation and expansion study of the BCL2 inhibitor venetoclax combined with tamoxifen in ER and BCL2-positive metastatic breast cancer

Lok, S. W., Whittle, J. R., Vaillant, F., Teh, C. E., Lo, L. L., Policheni, A. N., Bergin, A. R. T., Desai, J., Ftouni, S., Gandolfo, L. C., et al. (2019) · Cancer Discovery

Advanced Breast Cancer TherapiesBreast Cancer Treatment Studies

Cited by 148

Barcoding reveals complex clonal behavior in patient-derived xenografts of metastatic triple negative breast cancer

Merino, D., Weber, T. S., Serrano, A., Vaillant, F., Liu, K., Pal, B., Di Stefano, L., Schreuder, J., Lin, D., Chen, Y., et al. (2019) · Nature Communications

Cancer Genomics and DiagnosticsCancer Cells and Metastasis

Cited by 145

Dual targeting of CDK4/6 and BCL2 pathways augments tumor response in estrogen receptor-positive breast cancer

Whittle, J. R., Vaillant, F., Surgenor, E., Policheni, A. N., Giner, G., Capaldo, B. D., Chen, H.-R., Liu, H. K., Dekkers, J. F., Sachs, N., et al. (2020) · Clinical Cancer Research

Advanced Breast Cancer TherapiesBreast Cancer Treatment Studies

Cited by 102

Lgr5 + pericentral hepatocytes are self-maintained in normal liver regeneration and susceptible to hepatocarcinogenesis

Ang, C. H., Hsu, S. H., Guo, F., Tan, C. T., Yu, V. C., Visvader, J. E., Chow, P. K. H., & Fu, N. Y. (2019) · Proceedings of the National Academy of Sciences

Liver physiology and pathologyHepatocellular Carcinoma Treatment and Prognosis

Cited by 102

Scribble modulates the MAPK/Fra1 pathway to disrupt luminal and ductal integrity and suppress tumour formation in the mammary gland

Godde, N. J., Sheridan, J. M., Smith, L. K., Pearson, H. B., Britt, K. L., Galea, R. C., Yates, L. L., Visvader, J. E., & Humbert, P. O. (2014) · PLoS Genetics

Developmental Biology and Gene RegulationCancer Cells and Metastasis

Cited by 60

Targeting triple-negative breast cancers with the Smac-mimetic birinapant

Lalaoui, N., Merino, D., Giner, G., Vaillant, F., Chau, D., Liu, L., Kratina, T., Pal, B., Whittle, J. R., Etemadi, N., et al. (2020) · Cell Death & Differentiation

Cell death mechanisms and regulationHistone Deacetylase Inhibitors Research

Cited by 51