Pierce, Sarah E.

ArchR is a scalable software package for integrative single-cell chromatin accessibility analysis

Granja, J. M., Corces, M. R., Pierce, S. E., Bagdatli, S. T., Choudhry, H., Chang, H. Y., & Greenleaf, W. J. (2021) · Nature Genetics

Single-cell and spatial transcriptomicsGenomics and Chromatin Dynamics

Cited by 1,392

Massively parallel single-cell chromatin landscapes of human immune cell development and intratumoral T cell exhaustion

Satpathy, A. T., Granja, J. M., Yost, K. E., Qi, Y., Meschi, F., McDermott, G. P., Olsen, B. N., Mumbach, M. R., Pierce, S. E., Corces, M. R., et al. (2019) · Nature Biotechnology

Single-cell and spatial transcriptomicsGenomics and Chromatin Dynamics

Cited by 980

CRISPR screens in cancer spheroids identify 3D growth-specific vulnerabilities

Han, K., Pierce, S. E., Li, A., Spees, K., Anderson, G. R., Seoane, J. A., Lo, Y.-H., Dubreuil, M., Olivas, M., Kamber, R. A., et al. (2020) · Nature

CRISPR and Genetic EngineeringCancer Genomics and Diagnostics

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High-throughput single-cell chromatin accessibility CRISPR screens enable unbiased identification of regulatory networks in cancer

Pierce, S. E., Granja, J. M., & Greenleaf, W. J. (2021) · Nature Communications

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 146

LKB1 inactivation modulates chromatin accessibility to drive metastatic progression

Pierce, S. E., Granja, J. M., Corces, M. R., Brady, J. J., Tsai, M. K., Pierce, A. B., Tang, R., Chu, P., Feldser, D. M., Chang, H. Y., et al. (2021) · Nature Cell Biology

Chromatin Remodeling and CancerCancer Cells and Metastasis

Cited by 59

LKB1 drives stasis and C/EBP-mediated reprogramming to an alveolar type II fate in lung cancer

Murray, C. W., Brady, J. J., Han, M., Cai, H., Tsai, M. K., Pierce, S. E., Cheng, R., Demeter, J., Feldser, D. M., Jackson, P. K., et al. (2022) · Nature Communications

Lung Cancer Research StudiesLung Cancer Treatments and Mutations

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