Siliciano, Janet D.

Latent infection of CD4+ T cells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapy

Finzi, D., Blankson, J., Siliciano, J. D., Margolick, J. B., Chadwick, K., Pierson, T., Smith, K., Lisziewicz, J., Lori, F., Flexner, C., et al. (1999) · Nature Medicine

HIV Research and TreatmentHIV/AIDS drug development and treatment

Cited by 2,119

Activation of the ATM Kinase by Ionizing Radiation and Phosphorylation of p53

Canman, C. E., Lim, D.-S., Cimprich, K. A., Taya, Y., Tamai, K., Sakaguchi, K., Appella, E., Kastan, M. B., & Siliciano, J. D. (1998) · Science

DNA Repair MechanismsCancer-related Molecular Pathways

Cited by 2,042

Long-term follow-up studies confirm the stability of the latent reservoir for HIV-1 in resting CD4+ T cells

Siliciano, J. D., Kajdas, J., Finzi, D., Quinn, T. C., Chadwick, K., Margolick, J. B., Kovacs, C., Gange, S. J., & Siliciano, R. F. (2003) · Nature Medicine

HIV Research and TreatmentHIV/AIDS drug development and treatment

Cited by 1,703

Replication-competent noninduced proviruses in the latent reservoir increase barrier to HIV-1 cure

Ho, Y.-C., Shan, L., Hosmane, N. N., Wang, J., Laskey, S. B., Rosenbloom, D. I. S., Lai, J., Blankson, J. N., Siliciano, J. D., & Siliciano, R. F. (2013) · Cell

HIV Research and TreatmentVirus-based gene therapy research

Cited by 1,405

DNA damage induces phosphorylation of the amino terminus of p53

Siliciano, J. D., Canman, C. E., Taya, Y., Sakaguchi, K., Appella, E., & Kastan, M. B. (1997) · Genes & Development

Cancer-related Molecular PathwaysDNA Repair Mechanisms

Cited by 818

Defective proviruses rapidly accumulate during acute HIV-1 infection

Bruner, K. M., Murray, A. J., Pollack, R. A., Soliman, M. G., Laskey, S. B., Capoferri, A. A., Lai, J., Strain, M. C., Lada, S. M., Hoh, R., et al. (2016) · Nature Medicine

HIV Research and TreatmentHIV/AIDS drug development and treatment

Cited by 737

A quantitative approach for measuring the reservoir of latent HIV-1 proviruses

Bruner, K. M., Wang, Z., Simonetti, F. R., Bender, A. M., Kwon, K. J., Sengupta, S., Fray, E. J., Beg, S. A., Antar, A. A. R., Jenike, K. M., et al. (2019) · Nature

HIV Research and TreatmentVirus-based gene therapy research

Cited by 718