Gregorevic, Paul

Systemic delivery of genes to striated muscles using adeno-associated viral vectors

Gregorevic, P., Blankinship, M. J., Allen, J. M., Crawford, R. W., Meuse, L., Miller, D. G., Russell, D. W., & Chamberlain, J. S. (2004) · Nature Medicine

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 620

Functional screening in human cardiac organoids reveals a metabolic mechanism for cardiomyocyte cell cycle arrest

Mills, R. J., Titmarsh, D. M., Koenig, X., Parker, B. L., Ryall, J. G., Quaife-Ryan, G. A., Voges, H. K., Hodson, M. P., Ferguson, C., Drowley, L., et al. (2017) · Proceedings of the National Academy of Sciences

Pluripotent Stem Cells ResearchCongenital heart defects research

Cited by 478

Design of tissue-specific regulatory cassettes for high-level rAAV-mediated expression in skeletal and cardiac muscle

Salva, M. Z., Himeda, C. L., Tai, P. W., Nishiuchi, E., Gregorevic, P., Allen, J. M., Finn, E. E., Nguyen, Q. G., Blankinship, M. J., Meuse, L., et al. (2007) · Molecular Therapy

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 232

The bone morphogenetic protein axis is a positive regulator of skeletal muscle mass

Winbanks, C. E., Chen, J. L., Qian, H., Liu, Y., Bernardo, B. C., Beyer, C., Watt, K. I., Thomson, R. E., Connor, T., Turner, B. J., et al. (2013) · Journal of Cell Biology

Muscle Physiology and DisordersTGF-β signaling in diseases

Cited by 225

Follistatin-mediated skeletal muscle hypertrophy is regulated by Smad3 and mTOR independently of myostatin

Winbanks, C. E., Weeks, K. L., Thomson, R. E., Sepulveda, P. V., Beyer, C., Qian, H., Chen, J. L., Allen, J. M., Lancaster, G. I., Febbraio, M. A., et al. (2012) · Journal of Cell Biology

Muscle Physiology and DisordersTGF-β signaling in diseases

Cited by 218

TGFβ and BMP signaling in skeletal muscle: potential significance for muscle-related disease

Sartori, R., Gregorevic, P., & Sandri, M. (2014) · Trends in Endocrinology & Metabolism

Muscle Physiology and DisordersTGF-β signaling in diseases

Cited by 177

The Hippo pathway effector YAP is a critical regulator of skeletal muscle fibre size

Watt, K. I., Turner, B. J., Hagg, A., Zhang, X., Davey, J. R., Qian, H., Beyer, C., Winbanks, C. E., Harvey, K. F., & Gregorevic, P. (2015) · Nature Communications

Hippo pathway signaling and YAP/TAZMuscle Physiology and Disorders

Cited by 164

Systemic Microdystrophin Gene Delivery Improves Skeletal Muscle Structure and Function in Old Dystrophic mdx Mice

Gregorevic, P., Blankinship, M. J., Allen, J. M., & Chamberlain, J. S. (2008) · Molecular Therapy

Virus-based gene therapy researchMuscle Physiology and Disorders

Cited by 120

Specific targeting of TGF-β family ligands demonstrates distinct roles in the regulation of muscle mass in health and disease

Chen, J. L., Walton, K. L., Hagg, A., Colgan, T. D., Johnson, K., Qian, H., Gregorevic, P., & Harrison, C. A. (2017) · Proceedings of the National Academy of Sciences

Muscle Physiology and DisordersTGF-β signaling in diseases

Cited by 116

Gene Therapy of mdx Mice With Large Truncated Dystrophins Generated by Recombination Using rAAV6

Odom, G. L., Gregorevic, P., Allen, J. M., & Chamberlain, J. S. (2011) · Molecular Therapy

Virus-based gene therapy researchNeurogenetic and Muscular Disorders Research

Cited by 95

Smad7 gene delivery prevents muscle wasting associated with cancer cachexia in mice

Winbanks, C. E., Murphy, K. T., Bernardo, B. C., Qian, H., Liu, Y., Sepulveda, P. V., Beyer, C., Hagg, A., Thomson, R. E., Chen, J. L., et al. (2016) · Science Translational Medicine

Muscle Physiology and DisordersNutrition and Health in Aging

Cited by 95

Treatment of type 2 diabetes with the designer cytokine IC7Fc

Findeisen, M., Allen, T. L., Henstridge, D. C., Kammoun, H., Brandon, A. E., Baggio, L. L., Watt, K. I., Pal, M., Cron, L., Estevez, E., et al. (2019) · Nature

Cytokine Signaling Pathways and InteractionsAdipokines, Inflammation, and Metabolic Diseases

Cited by 86

Integrated expression analysis of muscle hypertrophy identifies Asb2 as a negative regulator of muscle mass

Davey, J. R., Watt, K. I., Parker, B. L., Chaudhuri, R., Ryall, J. G., Cunningham, L., Qian, H., Sartorelli, V., Sandri, M., Chamberlain, J., et al. (2016) · JCI Insight

Muscle Physiology and DisordersTGF-β signaling in diseases

Cited by 51

Evaluation of vascular delivery methodologies to enhance rAAV6-mediated gene transfer to canine striated musculature

Gregorevic, P., Schultz, B. R., Allen, J. M., Halldorson, J. B., Blankinship, M. J., Meznarich, N. A., Kuhr, C. S., Doremus, C., Finn, E., Liggitt, D., et al. (2009) · Molecular Therapy

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 40

Activin A–Induced Cachectic Wasting Is Attenuated by Systemic Delivery of Its Cognate Propeptide in Male Mice

Walton, K. L., Chen, J. L., Arnold, Q., Kelly, E., La, M., Lu, L., Lovrecz, G., Hagg, A., Colgan, T. D., Qian, H., et al. (2019) · Endocrinology

Muscle Physiology and DisordersNutrition and Health in Aging

Cited by 23

Class IIa HDACs inhibit cell death pathways and protect muscle integrity in response to lipotoxicity

Martin, S. D., Connor, T., Sanigorski, A., McEwen, K. A., Henstridge, D. C., Nijagal, B., De Souza, D., Tull, D. L., Meikle, P. J., Kowalski, G. M., et al. (2023) · Cell Death & Disease

Histone Deacetylase Inhibitors ResearchMuscle Physiology and Disorders

Cited by 16