Chun, Jerold

Integrative single-cell analysis of transcriptional and epigenetic states in the human adult brain

Lake, B. B., Chen, S., Sos, B. C., Fan, J., Kaeser, G. E., Yung, Y. C., Duong, T. E., Gao, D., Chun, J., Kharchenko, P. V., et al. (2018) · Nature Biotechnology

Single-cell and spatial transcriptomicsGenomics and Chromatin Dynamics

Cited by 983

Neuronal subtypes and diversity revealed by single-nucleus RNA sequencing of the human brain

Lake, B. B., Ai, R., Kaeser, G. E., Salathia, N. S., Yung, Y. C., Liu, R., Wildberg, A., Gao, D., Fung, H.-L., Chen, S., et al. (2016) · Science

Single-cell and spatial transcriptomicsGenomics and Phylogenetic Studies

Cited by 957

The lysophosphatidic acid receptor LPA1 links pulmonary fibrosis to lung injury by mediating fibroblast recruitment and vascular leak

Tager, A. M., LaCamera, P., Shea, B. S., Campanella, G. S., Selman, M., Zhao, Z., Polosukhin, V., Wain, J., Karimi-Shah, B. A., Kim, N. D., et al. (2008) · Nature Medicine

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisSphingolipid Metabolism and Signaling

Cited by 823

Comparative cellular analysis of motor cortex in human, marmoset and mouse

Bakken, T. E., Jorstad, N. L., Hu, Q., Lake, B. B., Tian, W., Kalmbach, B. E., Crow, M., Hodge, R. D., Krienen, F. M., Sorensen, S. A., et al. (2021) · Nature

Single-cell and spatial transcriptomicsNeuroscience and Neuropharmacology Research

Cited by 812

Evolution of cellular diversity in primary motor cortex of human, marmoset monkey, and mouse

Bakken, T. E., Jorstad, N. L., Hu, Q., Lake, B. B., Tian, W., Kalmbach, B. E., Crow, M., Hodge, R. D., Krienen, F. M., Sorensen, S. A., et al. (2020) · Nature

Single-cell and spatial transcriptomicsNeuroscience and Neuropharmacology Research

Cited by 809

Mechanism of Action of Oral Fingolimod (FTY720) in Multiple Sclerosis

Chun, J., & Hartung, H.-P. (2010) · Clinical Neuropharmacology

Multiple Sclerosis Research StudiesSphingolipid Metabolism and Signaling

Cited by 796

A multimodal cell census and atlas of the mammalian primary motor cortex

BRAIN Initiative Cell Census Network (BICCN), BRAIN Initiative Cell Census Network (BICCN) Corresponding authors, Callaway, E. M., Dong, H.-W., Ecker, J. R., Hawrylycz, M. J., Huang, Z. J., Lein, E. S., Ngai, J., Osten, P., et al. (2021) · Nature

Single-cell and spatial transcriptomicsGenomics and Chromatin Dynamics

Cited by 522

A comparative strategy for single-nucleus and single-cell transcriptomes confirms accuracy in predicted cell-type expression from nuclear RNA

Lake, B. B., Codeluppi, S., Yung, Y. C., Gao, D., Chun, J., Kharchenko, P. V., Linnarsson, S., & Zhang, K. (2017) · Scientific Reports

Single-cell and spatial transcriptomicsGenomics and Phylogenetic Studies

Cited by 271

Massively parallel polymerase cloning and genome sequencing of single cells using nanoliter microwells

Gole, J., Gore, A., Richards, A., Chiu, Y.-J., Fung, H.-L., Bushman, D., Chiang, H.-I., Chun, J., Lo, Y.-H., & Zhang, K. (2013) · Nature Biotechnology

Genomics and Phylogenetic StudiesSingle-cell and spatial transcriptomics

Cited by 238

Calcitonin controls bone formation by inhibiting the release of sphingosine 1-phosphate from osteoclasts

Keller, J., Catala-Lehnen, P., Huebner, A. K., Jeschke, A., Heckt, T., Lueth, A., Krause, M., Koehne, T., Albers, J., Schulze, J., et al. (2014) · Nature Communications

Bone Metabolism and DiseasesSphingolipid Metabolism and Signaling

Cited by 211

Somatic APP gene recombination in Alzheimer’s disease and normal neurons

Lee, M.-H., Siddoway, B., Kaeser, G. E., Segota, I., Rivera, R., Romanow, W. J., Liu, C. S., Park, C., Kennedy, G., Long, T., et al. (2018) · Nature

Alzheimer's disease research and treatmentsRNA Research and Splicing

Cited by 210

Ser18 and 23 phosphorylation is required for p53‐dependent apoptosis and tumor suppression

Chao, C., Herr, D., Chun, J., & Xu, Y. (2006) · The EMBO Journal

Cancer-related Molecular PathwaysDNA Repair Mechanisms

Cited by 158

The lysophosphatidic acid receptor LPA1 promotes epithelial cell apoptosis after lung injury

Funke, M., Zhao, Z., Xu, Y., Chun, J., & Tager, A. M. (2012) · American Journal of Respiratory Cell and Molecular Biology

Interstitial Lung Diseases and Idiopathic Pulmonary FibrosisSphingolipid Metabolism and Signaling

Cited by 141

Genomic mosaicism with increased amyloid precursor protein (APP) gene copy number in single neurons from sporadic Alzheimer's disease brains

Bushman, D. M., Kaeser, G. E., Siddoway, B., Westra, J. W., Rivera, R. R., Rehen, S. K., Yung, Y. C., & Chun, J. (2015) · eLife

Alzheimer's disease research and treatmentsGenomic variations and chromosomal abnormalities

Cited by 136

Fingolimod: Lessons Learned and New Opportunities for Treating Multiple Sclerosis and Other Disorders

Chun, J., Kihara, Y., Jonnalagadda, D., & Blaho, V. A. (2019) · Annual Review of Pharmacology and Toxicology

Sphingolipid Metabolism and SignalingMultiple Sclerosis Research Studies

Cited by 131

Sphingosine 1-phosphate receptor 3 and RhoA signaling mediate inflammatory gene expression in astrocytes

Dusaban, S. S., Chun, J., Rosen, H., Purcell, N. H., & Brown, J. H. (2017) · Journal of Neuroinflammation

Sphingolipid Metabolism and SignalingProtein Kinase Regulation and GTPase Signaling

Cited by 106

Altered cell and RNA isoform diversity in aging Down syndrome brains

Palmer, C. R., Liu, C. S., Romanow, W. J., Lee, M.-H., & Chun, J. (2021) · Proceedings of the National Academy of Sciences

Down syndrome and intellectual disability researchAlzheimer's disease research and treatments

Cited by 89

Hippocampal c-Fos activation in normal and LPA1-null mice after two object recognition tasks with different memory demands

Castilla-Ortega, E., Pedraza, C., Chun, J., Fonseca, F. R. D., Estivill-Torrús, G., & Santín, L. J. (2012) · Behavioural Brain Research

Memory and Neural MechanismsMemory Processes and Influences

Cited by 50

Single-Nucleus RNA-seq of Normal-Appearing Brain Regions in Relapsing-Remitting vs. secondary Progressive Multiple Sclerosis: implications for the Efficacy of fingolimod

Kihara, Y., Zhu, Y., Jonnalagadda, D., Romanow, W., Palmer, C., Siddoway, B., Rivera, R., Dutta, R., Trapp, B. D., & Chun, J. (2022) · Frontiers in Cellular Neuroscience

Multiple Sclerosis Research StudiesSingle-cell and spatial transcriptomics

Cited by 26