Elder, James T.

Pervasive Sharing of Genetic Effects in Autoimmune Disease

Cotsapas, C., Voight, B. F., Rossin, E., Lage, K., Neale, B. M., Wallace, C., Abecasis, G. R., Barrett, J. C., Behrens, T., Cho, J., et al. (2011) · PLoS Genetics

Genetic Associations and EpidemiologyMultiple Sclerosis Research Studies

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Atopic Dermatitis Is an IL-13–Dominant Disease with Greater Molecular Heterogeneity Compared to Psoriasis

Tsoi, L. C., Rodriguez, E., Degenhardt, F., Baurecht, H., Wehkamp, U., Volks, N., Szymczak, S., Swindell, W. R., Sarkar, M. K., Raja, K., et al. (2019) · Journal of Investigative Dermatology

Dermatology and Skin DiseasesPsoriasis: Treatment and Pathogenesis

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Application of retinol to human skin in vivo induces epidermal hyperplasia and cellular retinoid binding proteins characteristic of retinoic acid but without measurable retinoic acid levels or irritation

Kang, S., Duell, E. A., Fisher, G. J., Datta, S. C., Wang, Z.-Q., Reddy, A. P., Tavakkol, A., Yi, J. Y., Griffiths, C. E. M., Elder, J. T., et al. (1995) · Journal of Investigative Dermatology

Retinoids in leukemia and cellular processesSkin Protection and Aging

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Visualizing Human Leukocyte Antigen Class II Risk Haplotypes in Human Systemic Lupus Erythematosus

Graham, R. R., Ortmann, W. A., Langefeld, C. D., Jawaheer, D., Selby, S. A., Rodine, P. R., Baechler, E. C., Rohlf, K. E., Shark, K. B., Espe, K. J., et al. (2002) · The American Journal of Human Genetics

Systemic Lupus Erythematosus ResearchGenetic Associations and Epidemiology

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Genetic correlations among psychiatric and immune‐related phenotypes based on genome‐wide association data

Tylee, D. S., Sun, J., Hess, J. L., Tahir, M. A., Sharma, E., Malik, R., Worrall, B. B., Levine, A. J., Martinson, J. J., Nejentsev, S., et al. (2018) · American Journal of Medical Genetics Part B: Neuropsychiatric Genetics

Genetic Associations and EpidemiologyMultiple Sclerosis Research Studies

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Investigating the Causal Relationship of C-Reactive Protein with 32 Complex Somatic and Psychiatric Outcomes: A Large-Scale Cross-Consortium Mendelian Randomization Study

Prins, B. P., Abbasi, A., Wong, A., Vaez, A., Nolte, I., Franceschini, N., Stuart, P. E., Guterriez Achury, J., Mistry, V., Bradfield, J. P., et al. (2016) · PLOS Medicine

Genetic Associations and EpidemiologyAdipokines, Inflammation, and Metabolic Diseases

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Enhanced meta-analysis and replication studies identify five new psoriasis susceptibility loci

Tsoi, L. C., Spain, S. L., Ellinghaus, E., Stuart, P. E., Capon, F., Knight, J., Tejasvi, T., Kang, H. M., Allen, M. H., Lambert, S., et al. (2015) · Nature Communications

Psoriasis: Treatment and PathogenesisGenetic Associations and Epidemiology

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Genome-wide Comparative Analysis of Atopic Dermatitis and Psoriasis Gives Insight into Opposing Genetic Mechanisms

Baurecht, H., Hotze, M., Brand, S., Büning, C., Cormican, P., Corvin, A., Ellinghaus, D., Ellinghaus, E., Esparza-Gordillo, J., Fölster-Holst, R., et al. (2015) · The American Journal of Human Genetics

Dermatology and Skin DiseasesPsoriasis: Treatment and Pathogenesis

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Gene expression in skin and lymphoblastoid cells: refined statistical method reveals extensive overlap in cis-eQTL signals

Ding, J., Gudjonsson, J. E., Liang, L., Stuart, P. E., Li, Y., Chen, W., Weichenthal, M., Ellinghaus, E., Franke, A., Cookson, W., et al. (2010) · The American Journal of Human Genetics

Genetic Associations and EpidemiologyPsoriasis: Treatment and Pathogenesis

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A novel BH3 mimetic reveals a mitogen-activated protein kinase-dependent mechanism of melanoma cell death controlled by p53 and reactive oxygen species

Verhaegen, M., Bauer, J. A., Martín de la Vega, C., Wang, G., Wolter, K. G., Brenner, J. C., Nikolovska-Coleska, Z., Bengtson, A., Nair, R., Elder, J. T., et al. (2006) · Cancer Research

Cell death mechanisms and regulationMelanoma and MAPK Pathways

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A deep catalogue of protein-coding variation in 983,578 individuals

Sun, K. Y., Bai, X., Chen, S., Bao, S., Zhang, C., Kapoor, M., Backman, J., Joseph, T., Maxwell, E., Mitra, G., et al. (2024) · Nature

Genomics and Rare DiseasesGenetic Associations and Epidemiology

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Sebaceous Gland Atrophy in Psoriasis: An Explanation for Psoriatic Alopecia?

Rittié, L., Tejasvi, T., Harms, P. W., Xing, X., Nair, R. P., Gudjonsson, J. E., Swindell, W. R., & Elder, J. T. (2016) · Journal of Investigative Dermatology

Psoriasis: Treatment and PathogenesisHair Growth and Disorders

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Metalloproteinase-mediated, context-dependent function of amphiregulin and HB-EGF in human keratinocytes and skin

Stoll, S. W., Johnson, J. L., Bhasin, A., Johnston, A., Gudjonsson, J. E., Rittié, L., & Elder, J. T. (2010) · Journal of Investigative Dermatology

HER2/EGFR in Cancer ResearchWound Healing and Treatments

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Disease consequences of higher adiposity uncoupled from its adverse metabolic effects using Mendelian randomisation

Martin, S., Tyrrell, J., Thomas, E. L., Bown, M. J., Wood, A. R., Beaumont, R. N., Tsoi, L. C., Stuart, P. E., Elder, J. T., Law, P., et al. (2022) · eLife

Genetic Associations and EpidemiologyAdipokines, Inflammation, and Metabolic Diseases

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Integrative RNA-seq and microarray data analysis reveals GC content and gene length biases in the psoriasis transcriptome

Swindell, W. R., Xing, X., Voorhees, J. J., Elder, J. T., Johnston, A., & Gudjonsson, J. E. (2014) · Physiological Genomics

Gene expression and cancer classificationPsoriasis: Treatment and Pathogenesis

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