Redon, Christophe E.

Megabase Chromatin Domains Involved in DNA Double-Strand Breaks in Vivo

Rogakou, E. P., Boon, C., Redon, C., & Bonner, W. M. (1999) · The Journal of Cell Biology

DNA Repair MechanismsEffects of Radiation Exposure

Cited by 2,422

γH2AX and cancer

Bonner, W. M., Redon, C. E., Dickey, J. S., Nakamura, A. J., Sedelnikova, O. A., Solier, S., & Pommier, Y. (2008) · Nature reviews. Cancer

DNA Repair MechanismsEffects of Radiation Exposure

Cited by 1,623

Genomic Instability in Mice Lacking Histone H2AX

Celeste, A., Petersen, S., Romanienko, P. J., Fernandez-Capetillo, O., Chen, H. T., Sedelnikova, O. A., Reina-San-Martin, B., Coppola, V., Meffre, E., Difilippantonio, M. J., et al. (2002) · Science

DNA Repair MechanismsEffects of Radiation Exposure

Cited by 1,385

Use of the γ-H2AX assay to monitor DNA damage and repair in translational cancer research

Ivashkevich, A., Redon, C. E., Nakamura, A. J., Martin, R. F., & Martin, O. A. (2012) · Cancer Letters

DNA Repair MechanismsEffects of Radiation Exposure

Cited by 462

Phosphorylation of histone H2AX and activation of Mre11, Rad50, and Nbs1 in response to replication-dependent DNA double-strand breaks induced by mammalian DNA topoisomerase I cleavage complexes

Furuta, T., Takemura, H., Liao, Z.-Y., Aune, G. J., Redon, C., Sedelnikova, O. A., Pilch, D. R., Rogakou, E. P., Celeste, A., Chen, H. T., et al. (2003) · Journal of Biological Chemistry

DNA Repair MechanismsCancer therapeutics and mechanisms

Cited by 449

H2AX: functional roles and potential applications

Dickey, J. S., Redon, C. E., Nakamura, A. J., Baird, B. J., Sedelnikova, O. A., & Bonner, W. M. (2009) · Chromosoma

DNA Repair MechanismsEffects of Radiation Exposure

Cited by 320

SLFN11 Blocks Stressed Replication Forks Independently of ATR

Murai, J., Tang, S.-W., Leo, E., Baechler, S. A., Redon, C. E., Zhang, H., Al Abo, M., Rajapakse, V. N., Nakamura, E., Jenkins, L. M. M., et al. (2018) · Molecular Cell

DNA Repair MechanismsChromatin Remodeling and Cancer

Cited by 275

Delayed kinetics of DNA double‐strand break processing in normal and pathological aging

Sedelnikova, O. A., Horikawa, I., Redon, C., Nakamura, A., Zimonjic, D. B., Popescu, N. C., & Bonner, W. M. (2008) · Aging Cell

DNA Repair MechanismsTelomeres, Telomerase, and Senescence

Cited by 207

Histone variant H2A.J accumulates in senescent cells and promotes inflammatory gene expression

Contrepois, K., Coudereau, C., Benayoun, B. A., Schuler, N., Roux, P.-F., Bischof, O., Courbeyrette, R., Carvalho, C., Thuret, J.-Y., Ma, Z., et al. (2017) · Nature Communications

Telomeres, Telomerase, and SenescenceGenomics and Chromatin Dynamics

Cited by 191

Optimal function of the DNA repair enzyme TDP1 requires its phosphorylation by ATM and/or DNA‐PK

Das, B. B., Antony, S., Gupta, S., Dexheimer, T. S., Redon, C. E., Garfield, S., Shiloh, Y., & Pommier, Y. (2009) · The EMBO Journal

DNA Repair MechanismsCancer therapeutics and mechanisms

Cited by 151

Mito-Tempol and Dexrazoxane Exhibit Cardioprotective and Chemotherapeutic Effects through Specific Protein Oxidation and Autophagy in a Syngeneic Breast Tumor Preclinical Model

Dickey, J. S., Gonzalez, Y., Aryal, B., Mog, S., Nakamura, A. J., Redon, C. E., Baxa, U., Rosen, E., Cheng, G., Zielonka, J., et al. (2013) · PLoS ONE

Chemotherapy-induced cardiotoxicity and mitigationBioactive Compounds and Antitumor Agents

Cited by 60

Collaborative roles of γH2AX and the Rad51 paralog Xrcc3 in homologous recombinational repair

Sonoda, E., Zhao, G. Y., Kohzaki, M., Dhar, P. K., Kikuchi, K., Redon, C., Pilch, D. R., Bonner, W. M., Nakano, A., Watanabe, M., et al. (2007) · DNA Repair

DNA Repair MechanismsEffects of Radiation Exposure

Cited by 47

SOD2 deficiency promotes aging phenotypes in mouse skin

Weyemi, U., Parekh, P. R., Redon, C. E., & Bonner, W. M. (2012) · Aging

Redox biology and oxidative stressGenetics, Aging, and Longevity in Model Organisms

Cited by 30

Abstract CT268: Targeting replication stress and chemotherapy resistance with a combination of sacituzumab govitecan and berzosertib: A phase I clinical trial

Abel, M. L., Takahashi, N., Desai, P., Peer, C., Redon, C., Nichols, S., Vilimas, R., Lee, M.-J., Lee, S., Sciuto, L., et al. (2023) · Cancer Research

Cancer therapeutics and mechanismsPARP inhibition in cancer therapy

Cited by 4