Gentles, Andrew J.

Robust enumeration of cell subsets from tissue expression profiles

Newman, A. M., Liu, C. L., Green, M. R., Gentles, A. J., Feng, W., Xu, Y., Hoang, C. D., Diehn, M., & Alizadeh, A. A. (2015) · Nature Methods

Single-cell and spatial transcriptomicsGene expression and cancer classification

Cited by 13,224

The Immune Landscape of Cancer

Thorsson, V., Gibbs, D. L., Brown, S. D., Wolf, D., Bortone, D. S., Ou Yang, T.-H., Porta-Pardo, E., Gao, G. F., Plaisier, C. L., Eddy, J. A., et al. (2018) · Immunity

Cancer Immunotherapy and BiomarkersImmune cells in cancer

Cited by 5,870

Machine Learning Identifies Stemness Features Associated with Oncogenic Dedifferentiation

Malta, T. M., Sokolov, A., Gentles, A. J., Burzykowski, T., Poisson, L., Weinstein, J. N., Kamińska, B., Huelsken, J., Omberg, L., Gevaert, O., et al. (2018) · Cell

Cancer Cells and MetastasisPluripotent Stem Cells Research

Cited by 2,180

Calreticulin Is the Dominant Pro-Phagocytic Signal on Multiple Human Cancers and Is Counterbalanced by CD47

Chao, M. P., Jaiswal, S., Weissman-Tsukamoto, R., Alizadeh, A. A., Gentles, A. J., Volkmer, J., Weiskopf, K., Willingham, S. B., Raveh, T., Park, C. Y., et al. (2010) · Science Translational Medicine

Phagocytosis and Immune RegulationCell death mechanisms and regulation

Cited by 776

Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequences

Broad Institute Genome Sequencing Platform, Mikkelsen, T. S., Broad Institute Whole Genome Assembly Team, Wakefield, M. J., Aken, B., Amemiya, C. T., Chang, J. L., Duke, S., Garber, M., Gentles, A. J., et al. (2007) · Nature

Chromosomal and Genetic VariationsGenomics and Phylogenetic Studies

Cited by 711

Multimodal data fusion for cancer biomarker discovery with deep learning

Steyaert, S., Pizurica, M., Nagaraj, D., Khandelwal, P., Hernandez-Boussard, T., Gentles, A. J., & Gevaert, O. (2023) · Nature Machine Intelligence

Radiomics and Machine Learning in Medical ImagingMachine Learning in Healthcare

Cited by 402

CRISPR screens in cancer spheroids identify 3D growth-specific vulnerabilities

Han, K., Pierce, S. E., Li, A., Spees, K., Anderson, G. R., Seoane, J. A., Lo, Y.-H., Dubreuil, M., Olivas, M., Kamber, R. A., et al. (2020) · Nature

CRISPR and Genetic EngineeringCancer Genomics and Diagnostics

Cited by 311

Evolutionary dynamics of transposable elements in the short-tailed opossum Monodelphis domestica

Gentles, A. J., Wakefield, M. J., Kohany, O., Gu, W., Batzer, M. A., Pollock, D. D., & Jurka, J. (2007) · Genome Research

Chromosomal and Genetic VariationsEvolution and Paleontology Studies

Cited by 156

Identification of cell types in multiplexed in situ images by combining protein expression and spatial information using CELESTA

Zhang, W., Li, I., Reticker-Flynn, N. E., Good, Z., Chang, S., Samusik, N., Saumyaa, S., Li, Y., Zhou, X., Liang, R., et al. (2022) · Nature Methods

Single-cell and spatial transcriptomicsCell Image Analysis Techniques

Cited by 108

Translatome analysis reveals microglia and astrocytes to be distinct regulators of inflammation in the hyperacute and acute phases after stroke

Hernandez, V. G., Lechtenberg, K. J., Peterson, T. C., Zhu, L., Lucas, T. A., Owah, J. O., Dorsey, A. I., Gentles, A. J., & Buckwalter, M. S. (2023) · Glia

Neuroinflammation and Neurodegeneration MechanismsAcute Ischemic Stroke Management

Cited by 51

Translatome analysis reveals microglia and astrocytes to be distinct regulators of inflammation in the hyperacute and acute phases after stroke

Hernandez, V. G., Lechtenberg, K. J., Peterson, T. C., Zhu, L., Lucas, T. A., Bradshaw, K. P., Owah, J. O., Dorsey, A. I., Gentles, A. J., & Buckwalter, M. S. (2023) · Glia

Neuroinflammation and Neurodegeneration MechanismsAcute Ischemic Stroke Management

Cited by 51

SINEs, evolution and genome structure in the opossum

Gu, W., Ray, D. A., Walker, J. A., Barnes, E. W., Gentles, A. J., Samollow, P. B., Jurka, J., Batzer, M. A., & Pollock, D. D. (2007) · Gene

Chromosomal and Genetic VariationsGenetic diversity and population structure

Cited by 18

Transient “rest” induces functional reinvigoration and epigenetic remodeling in exhausted CAR-T cells

Weber, E. W., Lynn, R. C., Parker, K. R., Anbunathan, H., Lattin, J., Sotillo, E., Good, Z., Malipatlolla, M., Xu, P., Vandris, P., et al. (2020) · bioRxiv (Cold Spring Harbor Laboratory)

CAR-T cell therapy researchT-cell and B-cell Immunology

Cited by 18

An Atlas of Clinically-Distinct Tumor Cellular Ecosystems in Diffuse Large B Cell Lymphoma

Steen, C. B., Luca, B. A., Esfahani, M. S., Nabet, B. Y., Sworder, B., Farshidfar, F., Shamardani, K., Kurtz, D. M., Liu, C. L., Advani, R. H., et al. (2019) · Blood

Lymphoma Diagnosis and TreatmentSingle-cell and spatial transcriptomics

Cited by 4