Hanger, Diane P.

Roles of tau protein in health and disease

Guo, T., Noble, W., & Hanger, D. P. (2017) · Acta Neuropathologica

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 1,003

Tau phosphorylation: the therapeutic challenge for neurodegenerative disease

Hanger, D. P., Anderton, B. H., & Noble, W. (2009) · Trends in Molecular Medicine

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 965

Glycogen synthase kinase-3 induces Alzheimer's disease-like phosphorylation of tau: Generation of paired helical filament epitopes and neuronal localisation of the kinase

Hanger, D. P., Hughes, K., Woodgett, J. R., Brion, J.-P., & Anderton, B. H. (1992) · Neuroscience Letters

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 737

Physiological release of endogenous tau is stimulated by neuronal activity

Pooler, A. M., Phillips, E. C., Lau, D. H. W., Noble, W., & Hanger, D. P. (2013) · The EMBO Reports

Alzheimer's disease research and treatmentsNeuroscience and Neuropharmacology Research

Cited by 642

The importance of tau phosphorylation for neurodegenerative diseases

Noble, W., Hanger, D. P., Miller, C. C. J., & Lovestone, S. (2013) · Frontiers in Neurology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 475

Novel phosphorylation sites in tau from Alzheimer brain support a role for casein kinase 1 in disease pathogenesis

Hanger, D. P., Byers, H. L., Wray, S., Leung, K.-Y., Saxton, M. J., Seereeram, A., Reynolds, C. H., Ward, M. A., & Anderton, B. H. (2007) · Journal of Biological Chemistry

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 455

Astrocytes are important mediators of Aβ-induced neurotoxicity and tau phosphorylation in primary culture

Garwood, C. J., Pooler, A. M., Atherton, J., Hanger, D. P., & Noble, W. (2011) · Cell Death & Disease

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 379

A role for tau at the synapse in Alzheimer’s disease pathogenesis

Pooler, A. M., Noble, W., & Hanger, D. P. (2014) · Neuropharmacology

Alzheimer's disease research and treatmentsNeuroscience and Neuropharmacology Research

Cited by 203

Dynamic association of tau with neuronal membranes is regulated by phosphorylation

Pooler, A. M., Usardi, A., Evans, C. J., Philpott, K. L., Noble, W., & Hanger, D. P. (2012) · Neurobiology of Aging

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 148

Anti-Inflammatory Impact of Minocycline in a Mouse Model of Tauopathy

Garwood, C. J., Cooper, J. D., Hanger, D. P., & Noble, W. (2010) · Frontiers in Psychiatry

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 106

Mediators of tau phosphorylation in the pathogenesis of Alzheimer’s disease

Hanger, D. P., Seereeram, A., & Noble, W. (2009) · Expert Review of Neurotherapeutics

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 98

Direct analysis of tau from PSP brain identifies new phosphorylation sites and a major fragment of N‐terminally cleaved tau containing four microtubule‐binding repeats

Wray, S., Saxton, M., Anderton, B. H., & Hanger, D. P. (2008) · Journal of Neurochemistry

Alzheimer's disease research and treatmentsParkinson's Disease Mechanisms and Treatments

Cited by 97

Kinase activities increase during the development of tauopathy in htau mice

Kelleher, I., Garwood, C., Hanger, D. P., Anderton, B. H., & Noble, W. (2007) · Journal of Neurochemistry

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 78

Quantitative analysis of tau isoform transcripts in sporadic tauopathies

Connell, J. W., Rodriguez-Martin, T., Gibb, G. M., Kahn, N. M., Grierson, A. J., Hanger, D. P., Revesz, T., Lantos, P. L., Anderton, B. H., & Gallo, J.-M. (2005) · Molecular Brain Research

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 70

Reactive astrocytes secrete the chaperone HSPB1 to mediate neuroprotection

Yang, F., Beltran-Lobo, P., Sung, K., Goldrick, C., Croft, C. L., Nishimura, A., Hedges, E., Mahiddine, F., Troakes, C., Golde, T. E., et al. (2024) · Science Advances

Heat shock proteins researchNeuroinflammation and Neurodegeneration Mechanisms

Cited by 46