Abraham, David J.

TGF-β signaling and the fibrotic response

Leask, A., & Abraham, D. J. (2004) · The FASEB Journal

Connective Tissue Growth Factor ResearchTGF-β signaling in diseases

Cited by 2,319

Endothelial to mesenchymal transition contributes to endothelial dysfunction in pulmonary arterial hypertension

Good, R. B., Gilbane, A. J., Trinder, S. L., Denton, C. P., Coghlan, G., Abraham, D. J., & Holmes, A. M. (2015) · The American Journal of Pathology

Pulmonary Hypertension Research and TreatmentsSystemic Sclerosis and Related Diseases

Cited by 349

Fibroblast matrix gene expression and connective tissue remodeling: role of endothelin-1

Shi-wen, X., Denton, C. P., Holmes, A. M., Black, C. M., Abraham, D. J., Dashwood, M. R., Bou-Gharios, G., & Pearson, J. D. (2001) · Journal of Investigative Dermatology

Systemic Sclerosis and Related DiseasesNitric Oxide and Endothelin Effects

Cited by 243

Shared expression of phenotypic markers in systemic sclerosis indicates a convergence of pericytes and fibroblasts to a myofibroblast lineage in fibrosis

Rajkumar, V. S., Howell, K., Csiszar, K., Denton, C. P., Black, C. M., & Abraham, D. J. (2005) · Arthritis Research & Therapy

Systemic Sclerosis and Related DiseasesDupuytren's Contracture and Treatments

Cited by 242

Fibrosis in connective tissue disease: the role of the myofibroblast and fibroblast-epithelial cell interactions

Krieg, T., Abraham, D., & Lafyatis, R. (2007) · Arthritis Research & Therapy

Systemic Sclerosis and Related DiseasesInterstitial Lung Diseases and Idiopathic Pulmonary Fibrosis

Cited by 151

PDGFRα plays a crucial role in connective tissue remodeling

Horikawa, S., Ishii, Y., Hamashima, T., Yamamoto, S., Mori, H., Fujimori, T., Shen, J., Inoue, R., Nishizono, H., Itoh, H., et al. (2015) · Scientific Reports

Wound Healing and TreatmentsLiver physiology and pathology

Cited by 98

Changes in macrophage transcriptome associate with systemic sclerosis and mediate GSDMA contribution to disease risk

Moreno-Moral, A., Bagnati, M., Koturan, S., Ko, J.-H., Fonseca, C., Harmston, N., Game, L., Martin, J., Ong, V., Abraham, D. J., et al. (2018) · Annals of the Rheumatic Diseases

Systemic Sclerosis and Related DiseasesDupuytren's Contracture and Treatments

Cited by 78

Partially Evoked Epithelial-Mesenchymal Transition (EMT) Is Associated with Increased TGFβ Signaling within Lesional Scleroderma Skin

Nikitorowicz-Buniak, J., Denton, C. P., Abraham, D., & Stratton, R. (2015) · PLOS ONE

Systemic Sclerosis and Related DiseasesTGF-β signaling in diseases

Cited by 73

STAT3 controls COL1A2 enhancer activation cooperatively with JunB, regulates type I collagen synthesis posttranscriptionally, and is essential for lung myofibroblast differentiation

Papaioannou, I., Xu, S., Denton, C. P., Abraham, D. J., & Ponticos, M. (2018) · Molecular Biology of the Cell

Cytokine Signaling Pathways and InteractionsSystemic Sclerosis and Related Diseases

Cited by 64

The histone demethylase Jumonji domain-containing protein 3 (JMJD3) regulates fibroblast activation in systemic sclerosis

Bergmann, C., Brandt, A., Merlevede, B., Hallenberger, L., Dees, C., Wohlfahrt, T., Pötter, S., Zhang, Y., Chen, C.-W., Mallano, T., et al. (2018) · Annals of the Rheumatic Diseases

Systemic Sclerosis and Related DiseasesTGF-β signaling in diseases

Cited by 62