Zhou, Xiao Zhen

The prolyl isomerase Pin1 restores the function of Alzheimer-associated phosphorylated tau protein

Lu, P.-J., Wulf, G., Zhou, X. Z., Davies, P., & Lu, K. P. (1999) · Nature

Alzheimer's disease research and treatmentsSignaling Pathways in Disease

Cited by 721

The prolyl isomerase PIN1: a pivotal new twist in phosphorylation signalling and disease

Lu, K. P., & Zhou, X. Z. (2007) · Nature Reviews Molecular Cell Biology

Signaling Pathways in DiseaseProtein Kinase Regulation and GTPase Signaling

Cited by 682

The prolyl isomerase Pin1 regulates amyloid precursor protein processing and amyloid-β production

Pastorino, L., Sun, A., Lu, P.-J., Zhou, X. Z., Balastik, M., Finn, G., Wulf, G., Lim, J., Li, S.-H., Li, X., et al. (2006) · Nature

Alzheimer's disease research and treatmentsSignaling Pathways in Disease

Cited by 487

Antibody against early driver of neurodegeneration cis P-tau blocks brain injury and tauopathy

Kondo, A., Shahpasand, K., Mannix, R., Qiu, J., Moncaster, J., Chen, C.-H., Yao, Y., Lin, Y.-M., Driver, J. A., Sun, Y., et al. (2015) · Nature

Alzheimer's disease research and treatmentsTraumatic Brain Injury and Neurovascular Disturbances

Cited by 445

Active Pin1 is a key target of all-trans retinoic acid in acute promyelocytic leukemia and breast cancer

Wei, S., Kozono, S., Kats, L., Nechama, M., Li, W., Guarnerio, J., Luo, M., You, M.-H., Yao, Y., Kondo, A., et al. (2015) · Nature Medicine

Signaling Pathways in DiseaseRetinoids in leukemia and cellular processes

Cited by 272

Critical Role of WW Domain Phosphorylation in Regulating Phosphoserine Binding Activity and Pin1 Function

Lu, P.-J., Zhou, X. Z., Liou, Y.-C., Noel, J. P., & Lu, K. P. (2002) · Journal of Biological Chemistry

Signaling Pathways in DiseaseProtein Structure and Dynamics

Cited by 244

Arsenic targets Pin1 and cooperates with retinoic acid to inhibit cancer-driving pathways and tumor-initiating cells

Kozono, S., Lin, Y.-M., Seo, H.-S., Pinch, B., Lian, X., Qiu, C., Herbert, M. K., Chen, C.-H., Tan, L., Gao, Z. J., et al. (2018) · Nature Communications

Signaling Pathways in DiseaseRetinoids in leukemia and cellular processes

Cited by 168

Death-associated protein kinase 1 has a critical role in aberrant tau protein regulation and function

Kim, B. M., You, M.-H., Chen, C.-H., Lee, S., Hong, Y., Hong, Y., Kimchi, A., Zhou, X. Z., & Lee, T. H. (2014) · Cell Death & Disease

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 98

Binding and regulation of the transcription factor NFAT by the peptidyl prolyl cis–trans isomerase Pin1

Liu, W., Youn, H.-D., Zhou, X. Z., Lu, K. P., & Liu, J. O. (2001) · FEBS Letters

Signaling Pathways in DiseaseProtein Structure and Dynamics

Cited by 52