Conboy, Irina M.

Rejuvenation of aged progenitor cells by exposure to a young systemic environment

Conboy, I. M., Conboy, M. J., Wagers, A. J., Girma, E. R., Weissman, I. L., & Rando, T. A. (2005) · Nature

Genetics, Aging, and Longevity in Model OrganismsMesenchymal stem cell research

Cited by 2,287

Notch-Mediated Restoration of Regenerative Potential to Aged Muscle

Conboy, I. M., Conboy, M. J., Smythe, G. M., & Rando, T. A. (2003) · Science

Muscle Physiology and DisordersDevelopmental Biology and Gene Regulation

Cited by 1,121

Nanoparticle delivery of Cas9 ribonucleoprotein and donor DNA in vivo induces homology-directed DNA repair

Lee, K., Conboy, M., Park, H. M., Jiang, F., Kim, H. J., Dewitt, M. A., Mackley, V. A., Chang, K., Rao, A., Skinner, C., et al. (2017) · Nature Biomedical Engineering

CRISPR and Genetic EngineeringRNA Interference and Gene Delivery

Cited by 755

A Temporal Switch from Notch to Wnt Signaling in Muscle Stem Cells Is Necessary for Normal Adult Myogenesis

Brack, A. S., Conboy, I. M., Conboy, M. J., Shen, J., & Rando, T. A. (2008) · Cell Stem Cell

Muscle Physiology and DisordersDevelopmental Biology and Gene Regulation

Cited by 682

Oxytocin is an age-specific circulating hormone that is necessary for muscle maintenance and regeneration

Elabd, C., Cousin, W., Upadhyayula, P., Chen, R. Y., Chooljian, M. S., Li, J., Kung, S., Jiang, K. P., & Conboy, I. M. (2014) · Nature Communications

Muscle Physiology and DisordersNerve injury and regeneration

Cited by 411

A single heterochronic blood exchange reveals rapid inhibition of multiple tissues by old blood

Rebo, J., Mehdipour, M., Gathwala, R., Causey, K., Liu, Y., Conboy, M. J., & Conboy, I. M. (2016) · Nature Communications

Genetics, Aging, and Longevity in Model OrganismsTelomeres, Telomerase, and Senescence

Cited by 291

Heterochronic parabiosis: historical perspective and methodological considerations for studies of aging and longevity

Conboy, M. J., Conboy, I. M., & Rando, T. A. (2013) · Aging Cell

Genetics, Aging, and Longevity in Model OrganismsTelomeres, Telomerase, and Senescence

Cited by 265

Molecular aging and rejuvenation of human muscle stem cells

Carlson, M. E., Suetta, C., Conboy, M. J., Aagaard, P., Mackey, A., Kjaer, M., & Conboy, I. (2009) · EMBO Molecular Medicine

Muscle Physiology and DisordersGenetics, Aging, and Longevity in Model Organisms

Cited by 245

Relative roles of TGF‐β1 and Wnt in the systemic regulation and aging of satellite cell responses

Carlson, M. E., Conboy, M. J., Hsu, M., Barchas, L., Jeong, J., Agrawal, A., Mikels, A. J., Agrawal, S., Schaffer, D. V., & Conboy, I. M. (2009) · Aging Cell

Muscle Physiology and DisordersTGF-β signaling in diseases

Cited by 244

Heterochronic parabiosis for the study of the effects of aging on stem cells and their niches

Conboy, I. M., & Rando, T. A. (2012) · Cell Cycle

Genetics, Aging, and Longevity in Model OrganismsHematopoietic Stem Cell Transplantation

Cited by 239

Rejuvenation of three germ layers tissues by exchanging old blood plasma with saline-albumin

Mehdipour, M., Skinner, C., Wong, N., Lieb, M., Liu, C., Etienne, J., Kato, C., Kiprov, D., Conboy, M. J., & Conboy, I. M. (2020) · Aging

Genetics, Aging, and Longevity in Model OrganismsTelomeres, Telomerase, and Senescence

Cited by 115

Systemic induction of senescence in young mice after single heterochronic blood exchange

Jeon, O. H., Mehdipour, M., Gil, T.-H., Kang, M., Aguirre, N. W., Robinson, Z. R., Kato, C., Etienne, J., Lee, H. G., Alimirah, F., et al. (2022) · Nature Metabolism

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 114

Age dependent increase in the levels of osteopontin inhibits skeletal muscle regeneration

Paliwal, P., Pishesha, N., Wijaya, D., & Conboy, I. M. (2012) · Aging

Muscle Physiology and DisordersWound Healing and Treatments

Cited by 89