Bushman, Frederic D.

Commensal bacteria-derived signals regulate basophil hematopoiesis and allergic inflammation

Hill, D. A., Siracusa, M. C., Abt, M. C., Kim, B. S., Kobuley, D., Kubo, M., Kambayashi, T., LaRosa, D. F., Renner, E. D., Orange, J. S., et al. (2012) · Nature Medicine

Asthma and respiratory diseasesMast cells and histamine

Cited by 468

HIV integration site selection: Analysis by massively parallel pyrosequencing reveals association with epigenetic modifications

Wang, G. P., Ciuffi, A., Leipzig, J., Berry, C. C., & Bushman, F. D. (2007) · Genome Research

HIV Research and TreatmentGenomics and Chromatin Dynamics

Cited by 457

Disordered Microbial Communities in the Upper Respiratory Tract of Cigarette Smokers

Charlson, E. S., Chen, J., Custers-Allen, R., Bittinger, K., Li, H., Sinha, R., Hwang, J., Bushman, F. D., & Collman, R. G. (2010) · PLoS ONE

Oral microbiology and periodontitis researchGut microbiota and health

Cited by 437

A Modified γ-Retrovirus Vector for X-Linked Severe Combined Immunodeficiency

Hacein-Bey-Abina, S., Pai, S.-Y., Gaspar, H. B., Armant, M., Berry, C. C., Blanche, S., Bleesing, J., Blondeau, J., de Boer, H., Buckland, K. F., et al. (2014) · New England Journal of Medicine

Virus-based gene therapy researchImmunodeficiency and Autoimmune Disorders

Cited by 412

Activities of human immunodeficiency virus (HIV) integration protein in vitro: specific cleavage and integration of HIV DNA

Bushman, F. D., & Craigie, R. (1991) · Proceedings of the National Academy of Sciences

HIV Research and TreatmentHIV/AIDS drug development and treatment

Cited by 410

The IN protein of Moloney murine leukemia virus processes the viral DNA ends and accomplishes their integration in vitro

Craigie, R., Fujiwara, T., & Bushman, F. (1990) · Cell

T-cell and Retrovirus StudiesHIV Research and Treatment

Cited by 409

Retroviral DNA integration: viral and cellular determinants of target-site selection

Lewinski, M. K., Yamashita, M., Emerman, M., Ciuffi, A., Marshall, H., Crawford, G., Collins, F., Shinn, P., Leipzig, J., Hannenhalli, S., et al. (2006) · PLoS Pathogens

HIV Research and TreatmentVirus-based gene therapy research

Cited by 364

Lung-enriched Organisms and Aberrant Bacterial and Fungal Respiratory Microbiota after Lung Transplant

Charlson, E. S., Diamond, J. M., Bittinger, K., Fitzgerald, A. S., Yadav, A., Haas, A. R., Bushman, F. D., & Collman, R. G. (2012) · American Journal of Respiratory and Critical Care Medicine

Transplantation: Methods and OutcomesNosocomial Infections in ICU

Cited by 348

Retroviral DNA integration directed by HIV integration protein in vitro

Bushman, F. D., Fujiwara, T., & Craigie, R. (1990) · Science

HIV Research and TreatmentHIV/AIDS drug development and treatment

Cited by 338

HIV DNA Integration

Craigie, R., & Bushman, F. D. (2012) · Cold Spring Harbor Perspectives in Medicine

HIV Research and TreatmentHIV/AIDS drug development and treatment

Cited by 327

Gut microbiota modulate dendritic cell antigen presentation and radiotherapy-induced antitumor immune response

Uribe-Herranz, M., Rafail, S., Beghi, S., Gil-de-Gómez, L., Verginadis, I., Bittinger, K., Pustylnikov, S., Pierini, S., Perales-Linares, R., Blair, I. A., et al. (2019) · Journal of Clinical Investigation

Gut microbiota and healthCancer Immunotherapy and Biomarkers

Cited by 316

Role of PSIP1/LEDGF/p75 in Lentiviral Infectivity and Integration Targeting

Marshall, H. M., Ronen, K., Berry, C., Llano, M., Sutherland, H., Saenz, D., Bickmore, W., Poeschla, E., & Bushman, F. D. (2007) · PLoS ONE

Virus-based gene therapy researchHIV Research and Treatment

Cited by 241

Human immunodeficiency virus integrase directs integration to sites of severe DNA distortion within the nucleosome core.

Pruss, D., Bushman, F. D., & Wolffe, A. P. (1994) · Proceedings of the National Academy of Sciences

HIV Research and TreatmentGenomics and Chromatin Dynamics

Cited by 236

HIV Integration Targeting: A Pathway Involving Transportin-3 and the Nuclear Pore Protein RanBP2

Ocwieja, K. E., Brady, T. L., Ronen, K., Huegel, A., Roth, S. L., Schaller, T., James, L. C., Towers, G. J., Young, J. A. T., Chanda, S. K., et al. (2011) · PLoS Pathogens

HIV Research and TreatmentVirus-based gene therapy research

Cited by 212

Repair of gaps in retroviral DNA integration intermediates

Yoder, K. E., & Bushman, F. D. (2000) · Journal of Virology

DNA Repair MechanismsHIV Research and Treatment

Cited by 209

BET proteins promote efficient murine leukemia virus integration at transcription start sites

Sharma, A., Larue, R. C., Plumb, M. R., Malani, N., Male, F., Slaughter, A., Kessl, J. J., Shkriabai, N., Coward, E., Aiyer, S. S., et al. (2013) · Proceedings of the National Academy of Sciences

Virus-based gene therapy researchProtein Degradation and Inhibitors

Cited by 193

Gut microbiota modulates adoptive cell therapy via CD8α dendritic cells and IL-12

Uribe-Herranz, M., Bittinger, K., Rafail, S., Guedan, S., Pierini, S., Tanes, C., Ganetsky, A., Morgan, M. A., Gill, S., Tanyi, J. L., et al. (2018) · JCI Insight

Gut microbiota and healthImmunotherapy and Immune Responses

Cited by 175

The BET Family of Proteins Targets Moloney Murine Leukemia Virus Integration near Transcription Start Sites

De Rijck, J., de Kogel, C., Demeulemeester, J., Vets, S., El Ashkar, S., Malani, N., Bushman, F. D., Landuyt, B., Husson, S. J., Busschots, K., et al. (2013) · Cell Reports

Virus-based gene therapy researchProtein Degradation and Inhibitors

Cited by 175

The influence of DNA and nucleosome structure on integration events directed by HIV integrase

Pruss, D., Reeves, R., Bushman, F. D., & Wolffe, A. P. (1994) · Journal of Biological Chemistry

HIV Research and TreatmentDNA and Nucleic Acid Chemistry

Cited by 173

Multicenter comparison of lung and oral microbiomes of HIV-infected and HIV-uninfected individuals.

Beck, J. M., Schloss, P. D., Venkataraman, A., Twigg, H., Jablonski, K. A., Bushman, F. D., Campbell, T. B., Charlson, E. S., Collman, R. G., Crothers, K., et al. (2015) · American Journal of Respiratory and Critical Care Medicine

HIV/AIDS oral health manifestationsOral microbiology and periodontitis research

Cited by 150

A tool kit for quantifying eukaryotic rRNA gene sequences from human microbiome samples

Dollive, S., Peterfreund, G. L., Sherrill-Mix, S., Bittinger, K., Sinha, R., Hoffmann, C., Nabel, C. S., Hill, D. A., Artis, D., Bachman, M. A., et al. (2012) · Genome biology

Genomics and Phylogenetic StudiesEnvironmental DNA in Biodiversity Studies

Cited by 147

Directly Infected Resting CD4+T Cells Can Produce HIV Gag without Spreading Infection in a Model of HIV Latency

Pace, M. J., Graf, E. H., Agosto, L. M., Mexas, A. M., Male, F., Brady, T., Bushman, F. D., & O'Doherty, U. (2012) · PLoS Pathogens

HIV Research and TreatmentT-cell and Retrovirus Studies

Cited by 144

Engineering HIV-resistant human CD4+ T cells with CXCR4-specific zinc-finger nucleases

Wilen, C. B., Wang, J., Tilton, J. C., Miller, J. C., Kim, K. A., Rebar, E. J., Sherrill-Mix, S. A., Patro, S. C., Secreto, A. J., Jordan, A. P. O., et al. (2011) · PLoS Pathogens

HIV Research and TreatmentCRISPR and Genetic Engineering

Cited by 142

Community-Wide Response of the Gut Microbiota to Enteropathogenic Citrobacter rodentium Infection Revealed by Deep Sequencing

Hoffmann, C., Hill, D. A., Minkah, N., Kirn, T., Troy, A., Artis, D., & Bushman, F. (2009) · Infection and Immunity

Gut microbiota and healthEscherichia coli research studies

Cited by 142