Bushman, Frederic D.

Human and rat gut microbiome composition is maintained following sleep restriction

Zhang, S. L., Bai, L., Goel, N., Bailey, A., Jang, C. J., Bushman, F. D., Meerlo, P., Dinges, D. F., & Sehgal, A. (2017) · Proceedings of the National Academy of Sciences

Gut microbiota and healthGastrointestinal motility and disorders

Cited by 139

Retroviral integration and human gene therapy

Bushman, F. D. (2007) · Journal of Clinical Investigation

Virus-based gene therapy researchCAR-T cell therapy research

Cited by 138

A New Class of Multimerization Selective Inhibitors of HIV-1 Integrase

Sharma, A., Slaughter, A., Jena, N., Feng, L., Kessl, J. J., Fadel, H. J., Malani, N., Male, F., Wu, L., Poeschla, E., et al. (2014) · PLoS Pathogens

HIV/AIDS drug development and treatmentHIV Research and Treatment

Cited by 124

The Perioperative Lung Transplant Virome: Torque Teno Viruses Are Elevated in Donor Lungs and Show Divergent Dynamics in Primary Graft Dysfunction

Abbas, A. A., Diamond, J. M., Chehoud, C., Chang, B., Kotzin, J. J., Young, J. C., Imai, I., Haas, A. R., Cantu, E., Lederer, D. J., et al. (2017) · American Journal of Transplantation

Transplantation: Methods and OutcomesOrgan Transplantation Techniques and Outcomes

Cited by 112

Population structure of human gut bacteria in a diverse cohort from rural Tanzania and Botswana

Hansen, M. E. B., Rubel, M. A., Bailey, A. G., Ranciaro, A., Thompson, S. R., Campbell, M. C., Beggs, W., Dave, J. R., Mokone, G. G., Mpoloka, S. W., et al. (2019) · Genome Biology

Gut microbiota and healthMicrobial Community Ecology and Physiology

Cited by 110

Detecting contamination in viromes using ViromeQC

Zolfo, M., Pinto, F., Asnicar, F., Manghi, P., Tett, A., Bushman, F. D., & Segata, N. (2019) · Nature Biotechnology

Bacteriophages and microbial interactionsGenomics and Phylogenetic Studies

Cited by 103

Allosteric Inhibition of Human Immunodeficiency Virus Integrase

Gupta, K., Brady, T., Dyer, B. M., Malani, N., Hwang, Y., Male, F., Nolte, R. T., Wang, L., Velthuisen, E., Jeffrey, J., et al. (2014) · Journal of Biological Chemistry

HIV/AIDS drug development and treatmentHIV Research and Treatment

Cited by 81

Altering murine leukemia virus integration through disruption of the integrase and BET protein family interaction

Aiyer, S., Swapna, G. V. T., Malani, N., Aramini, J. M., Schneider, W. M., Plumb, M. R., Ghanem, M., Larue, R. C., Sharma, A., Studamire, B., et al. (2014) · Nucleic Acids Research

Virus-based gene therapy researchCRISPR and Genetic Engineering

Cited by 72

Gammaretroviral Integration into Nucleosomal Target DNA In Vivo

Roth, S. L., Malani, N., & Bushman, F. D. (2011) · Journal of Virology

Virus-based gene therapy researchGenomics and Chromatin Dynamics

Cited by 69

Structural Basis for Inhibitor-Induced Aggregation of HIV Integrase

Gupta, K., Turkki, V., Sherrill-Mix, S., Hwang, Y., Eilers, G., Taylor, L., McDanal, C., Wang, P., Temelkoff, D., Nolte, R. T., et al. (2016) · PLOS Biology

HIV/AIDS drug development and treatmentHIV Research and Treatment

Cited by 68

Viral DNA tethering domains complement replication-defective mutations in the p12 protein of MuLV Gag

Schneider, W. M., Brzezinski, J. D., Aiyer, S., Malani, N., Gyuricza, M., Bushman, F. D., & Roth, M. J. (2013) · Proceedings of the National Academy of Sciences

HIV Research and TreatmentT-cell and Retrovirus Studies

Cited by 49

Bimodal high-affinity association of Brd4 with murine leukemia virus integrase and mononucleosomes

Larue, R. C., Plumb, M. R., Crowe, B. L., Shkriabai, N., Sharma, A., DiFiore, J., Malani, N., Aiyer, S. S., Roth, M. J., Bushman, F. D., et al. (2014) · Nucleic Acids Research

Virus-based gene therapy researchProtein Degradation and Inhibitors

Cited by 44

The Competitive Interplay between Allosteric HIV-1 Integrase Inhibitor BI/D and LEDGF/p75 during the Early Stage of HIV-1 Replication Adversely Affects Inhibitor Potency

Feng, L., Dharmarajan, V., Serrao, E., Hoyte, A., Larue, R. C., Slaughter, A., Sharma, A., Plumb, M. R., Kessl, J. J., Fuchs, J. R., et al. (2016) · ACS Chemical Biology

HIV/AIDS drug development and treatmentHIV Research and Treatment

Cited by 37

Structural and sequencing analysis of local target DNA recognition by MLV integrase

Aiyer, S., Rossi, P., Malani, N., Schneider, W. M., Chandar, A., Bushman, F. D., Montelione, G. T., & Roth, M. J. (2015) · Nucleic Acids Research

HIV Research and TreatmentHIV/AIDS drug development and treatment

Cited by 25

Allosteric HIV Integrase Inhibitors Promote Formation of Inactive Branched Polymers via Homomeric Carboxy-Terminal Domain Interactions

Gupta, K., Allen, A., Giraldo, C., Eilers, G., Sharp, R., Hwang, Y., Murali, H., Cruz, K., Janmey, P., Bushman, F., et al. (2021) · Structure

HIV/AIDS drug development and treatmentHIV Research and Treatment

Cited by 19