Boghaert, Erwin R.

ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets

Souers, A. J., Leverson, J. D., Boghaert, E. R., Ackler, S. L., Catron, N. D., Chen, J., Dayton, B. D., Ding, H., Enschede, S. H., Fairbrother, W. J., et al. (2013) · Nature Medicine

Cell death mechanisms and regulationCancer-related Molecular Pathways

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Exploiting selective BCL-2 family inhibitors to dissect cell survival dependencies and define improved strategies for cancer therapy

Leverson, J. D., Phillips, D. C., Mitten, M. J., Boghaert, E. R., Diaz, D., Tahir, S. K., Belmont, L. D., Nimmer, P., Xiao, Y., Ma, X. M., et al. (2015) · Science Translational Medicine

Cell death mechanisms and regulationCancer-related Molecular Pathways

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Capturing tumor complexity in vitro: Comparative analysis of 2D and 3D tumor models for drug discovery

Stock, K., Estrada, M. F., Vidic, S., Gjerde, K., Rudisch, A., Santo, V. E., Barbier, M., Blom, S., Arundkar, S. C., Selvam, I., et al. (2016) · Scientific Reports

3D Printing in Biomedical ResearchCancer Cells and Metastasis

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SKI-606, a Src/Abl Inhibitor with In vivo Activity in Colon Tumor Xenograft Models

Golas, J. M., Lucas, J., Etienne, C., Golas, J., Discafani, C., Sridharan, L., Boghaert, E., Arndt, K., Ye, F., Boschelli, D. H., et al. (2005) · Cancer Research

Cancer Mechanisms and TherapyProtein Kinase Regulation and GTPase Signaling

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Application of LDH assay for therapeutic efficacy evaluation of ex vivo tumor models

Cox, M. C., Mendes, R., Silva, F., Mendes, T. F., Zelaya-Lazo, A., Halwachs, K., Purkal, J. J., Isidro, I. A., Félix, A., Boghaert, E. R., et al. (2021) · Scientific Reports

3D Printing in Biomedical ResearchCancer Cells and Metastasis

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Patient-derived Ovarian Cancer Explants: Preserved Viability and Histopathological Features in Long-Term Agitation-Based Cultures

Abreu, S., Silva, F., Mendes, R., Mendes, T. F., Teixeira, M., Santo, V. E., Boghaert, E. R., Félix, A., & Brito, C. (2020) · Scientific Reports

Ovarian cancer diagnosis and treatmentCancer Cells and Metastasis

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Pathophysiologic and Pharmacologic Considerations to Improve the Design and Application of Antibody–Drug Conjugates

Boghaert, E. R., Cox, M. C., & Vaidya, K. S. (2022) · Cancer Research

Monoclonal and Polyclonal Antibodies ResearchNanoparticle-Based Drug Delivery

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