Kapoor, Manav

A common haplotype lowers PU.1 expression in myeloid cells and delays onset of Alzheimer's disease

The International Genomics of Alzheimer's Project, Huang, K.-L., Initiative, T. A. D. N., Marcora, E., Pimenova, A. A., Di Narzo, A. F., Kapoor, M., Jin, S. C., Harari, O., Bertelsen, S., et al. (2017) · Nature Neuroscience

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 423

Cholesterol and matrisome pathways dysregulated in astrocytes and microglia

TCW, J., Qian, L., Pipalia, N. H., Chao, M. J., Liang, S. A., Shi, Y., Jain, B. R., Bertelsen, S. E., Kapoor, M., Marcora, E., et al. (2022) · Cell

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 411

Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction.

Karlsson Linnér, R., Mallard, T. T., Barr, P. B., Sanchez-Roige, S., Madole, J. W., Driver, M. N., Poore, H. E., de Vlaming, R., Grotzinger, A. D., Tielbeek, J. J., et al. (2021) · Nature Neuroscience

Genetic Associations and EpidemiologyNeurotransmitter Receptor Influence on Behavior

Cited by 317

Genome-wide association study identifies four novel loci associated with Alzheimer’s endophenotypes and disease modifiers

(ADNI), A. D. N. I., Deming, Y., The Alzheimer Disease Genetic Consortium (ADGC), Li, Z., Kapoor, M., Harari, O., Del-Aguila, J. L., Black, K., Carrell, D., Cai, Y., et al. (2017) · Acta Neuropathologica

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 231

Integration of Alzheimer’s disease genetics and myeloid genomics identifies disease risk regulatory elements and genes

Novikova, G., Kapoor, M., TCW, J., Abud, E. M., Efthymiou, A. G., Chen, S. X., Cheng, H., Fullard, J. F., Bendl, J., Liu, Y., et al. (2021) · Nature Communications

Alzheimer's disease research and treatmentsGenetic Associations and Epidemiology

Cited by 214

Polygenic risk score of sporadic late‐onset Alzheimer's disease reveals a shared architecture with the familial and early‐onset forms

Cruchaga, C., Del‐Aguila, J. L., Saef, B., Black, K., Fernandez, M. V., Budde, J., Ibanez, L., Deming, Y., Kapoor, M., Tosto, G., et al. (2018) · Alzheimer's & Dementia

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 138

Evidence of CNIH3 involvement in opioid dependence

Nelson, E. C., Agrawal, A., Heath, A. C., Bogdan, R., Sherva, R., Zhang, B., Al-Hasani, R., Bruchas, M. R., Chou, Y.-L., Demers, C. H., et al. (2016) · Molecular Psychiatry

Neurotransmitter Receptor Influence on BehaviorGenetic Associations and Epidemiology

Cited by 131

A deep catalogue of protein-coding variation in 983,578 individuals

Sun, K. Y., Bai, X., Chen, S., Bao, S., Zhang, C., Kapoor, M., Backman, J., Joseph, T., Maxwell, E., Mitra, G., et al. (2024) · Nature

Genomics and Rare DiseasesGenetic Associations and Epidemiology

Cited by 127

Single cell transcriptome profiling of the human alcohol-dependent brain

Brenner, E., Tiwari, G. R., Kapoor, M., Liu, Y., Brock, A., & Mayfield, R. D. (2020) · Human Molecular Genetics

Single-cell and spatial transcriptomicsAlcohol Consumption and Health Effects

Cited by 118

Paired Immunoglobulin-like Type 2 Receptor Alpha G78R variant alters ligand binding and confers protection to Alzheimer's disease

Rathore, N., Ramani, S. R., Pantua, H., Payandeh, J., Bhangale, T., Wuster, A., Kapoor, M., Sun, Y., Kapadia, S. B., Gonzalez, L., et al. (2018) · PLOS Genetics

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 93

Analysis of whole genome-transcriptomic organization in brain to identify genes associated with alcoholism

Kapoor, M., Wang, J.-C., Farris, S. P., Liu, Y., McClintick, J., Gupta, I., Meyers, J. L., Bertelsen, S., Chao, M., Nurnberger, J., et al. (2019) · Translational Psychiatry

Substance Abuse Treatment and OutcomesAlcohol Consumption and Health Effects

Cited by 92

Integration of Alzheimer’s disease genetics and myeloid genomics reveals novel disease risk mechanisms

Novikova, G., Kapoor, M., TCW, J., Abud, E. M., Efthymiou, A. G., Cheng, H., Fullard, J. F., Bendl, J., Roussos, P., Poon, W. W., et al. (2019) · Alzheimer s & Dementia

Alzheimer's disease research and treatmentsGenetic Associations and Epidemiology

Cited by 27

Ethanol treatment of lymphoblastoid cell lines from alcoholics and non-alcoholics causes many subtle changes in gene expression

McClintick, J. N., Brooks, A. I., Deng, L., Liang, L., Wang, J. C., Kapoor, M., Xuei, X., Foroud, T., Tischfield, J. A., & Edenberg, H. J. (2014) · Alcohol

Alcohol Consumption and Health EffectsSubstance Abuse Treatment and Outcomes

Cited by 25