Trefely, Sophie

Dietary fructose feeds hepatic lipogenesis via microbiota-derived acetate

Zhao, S., Jang, C., Liu, J., Uehara, K., Gilbert, M., Izzo, L., Zeng, X., Trefely, S., Fernandez, S., Carrer, A., et al. (2020) · Nature

Diet, Metabolism, and DiseaseLipid metabolism and biosynthesis

Cited by 553

Global Phosphoproteomic Analysis of Human Skeletal Muscle Reveals a Network of Exercise-Regulated Kinases and AMPK Substrates

Hoffman, N. J., Parker, B. L., Chaudhuri, R., Fisher-Wellman, K. H., Kleinert, M., Humphrey, S. J., Yang, P., Holliday, M., Trefely, S., Fazakerley, D. J., et al. (2015) · Cell Metabolism

Metabolism, Diabetes, and CancerMuscle metabolism and nutrition

Cited by 426

ATP-citrate lyase controls a glucose-to-acetate metabolic switch

Zhao, S., Torres, A., Henry, R. A., Trefely, S., Wallace, M., Lee, J. V., Carrer, A., Sengupta, A., Campbell, S. L., Kuo, Y.-M., et al. (2016) · Cell Reports

Cancer, Lipids, and MetabolismLipid metabolism and biosynthesis

Cited by 394

Acetyl-CoA Metabolism Supports Multistep Pancreatic Tumorigenesis

Carrer, A., Trefely, S., Zhao, S., Campbell, S. L., Norgard, R. J., Schultz, K. C., Sidoli, S., Parris, J. L. D., Affronti, H. C., Sivanand, S., et al. (2019) · Cancer Discovery

Cancer, Lipids, and MetabolismPancreatic and Hepatic Oncology Research

Cited by 313

Compartmentalised acyl-CoA metabolism and roles in chromatin regulation

Trefely, S., Lovell, C. D., Snyder, N. W., & Wellen, K. E. (2020) · Molecular Metabolism

Genomics and Chromatin DynamicsHistone Deacetylase Inhibitors Research

Cited by 272

Regulation of nuclear epigenome by mitochondrial DNA heteroplasmy

Kopinski, P. K., Janssen, K. A., Schaefer, P. M., Trefely, S., Perry, C. E., Potluri, P., Tintos-Hernandez, J. A., Singh, L. N., Karch, K. R., Campbell, S. L., et al. (2019) · Proceedings of the National Academy of Sciences

Mitochondrial Function and PathologyEpigenetics and DNA Methylation

Cited by 159

Glutamine deprivation triggers NAGK-dependent hexosamine salvage

Campbell, S., Mesaros, C., Izzo, L., Affronti, H., Noji, M., Schaffer, B. E., Tsang, T., Sun, K., Trefely, S., Kruijning, S., et al. (2021) · eLife

Glycosylation and Glycoproteins ResearchCancer, Hypoxia, and Metabolism

Cited by 58