Disney, Matthew D.

Poly(GP) proteins are a useful pharmacodynamic marker for C9ORF72 -associated amyotrophic lateral sclerosis

Gendron, T. F., Chew, J., Stankowski, J. N., Hayes, L. R., Zhang, Y.-J., Prudencio, M., Carlomagno, Y., Daughrity, L. M., Jansen-West, K., Perkerson, E. A., et al. (2017) · Science Translational Medicine

Amyotrophic Lateral Sclerosis ResearchAlzheimer's disease research and treatments

Cited by 265

Small Molecule Targeted Recruitment of a Nuclease to RNA

Costales, M. G., Matsumoto, Y., Velagapudi, S. P., & Disney, M. D. (2018) · Journal of the American Chemical Society

RNA Interference and Gene DeliveryDNA and Nucleic Acid Chemistry

Cited by 212

Targeting the SARS-CoV-2 RNA Genome with Small Molecule Binders and Ribonuclease Targeting Chimera (RIBOTAC) Degraders

Haniff, H. S., Tong, Y., Liu, X., Chen, J. L., Suresh, B. M., Andrews, R. J., Peterson, J. M., O’Leary, C. A., Benhamou, R. I., Moss, W. N., et al. (2020) · ACS Central Science

SARS-CoV-2 and COVID-19 ResearchDNA and Nucleic Acid Chemistry

Cited by 205

Thermodynamics of RNA−RNA Duplexes with 2- or 4-Thiouridines: Implications for Antisense Design and Targeting a Group I Intron

Testa, S. M., Disney, M. D., Turner, D. H., & Kierzek, R. (1999) · Biochemistry

DNA and Nucleic Acid ChemistryRNA and protein synthesis mechanisms

Cited by 122

Ribonuclease recruitment using a small molecule reduced c9ALS/FTD r(G 4 C 2 ) repeat expansion in vitro and in vivo ALS models

Bush, J. A., Aikawa, H., Fuerst, R., Li, Y., Ursu, A., Meyer, S. M., Benhamou, R. I., Chen, J. L., Khan, T., Wagner-Griffin, S., et al. (2021) · Science Translational Medicine

Amyotrophic Lateral Sclerosis ResearchGenetic Neurodegenerative Diseases

Cited by 77

Small molecule chemical probes of microRNA function

Velagapudi, S. P., Vummidi, B. R., & Disney, M. D. (2015) · Current Opinion in Chemical Biology

MicroRNA in disease regulationRNA Interference and Gene Delivery

Cited by 46