Binder, Elisabeth B.

Accelerated neurodegeneration through chaperone-mediated oligomerization of tau

Blair, L. J., Nordhues, B. A., Hill, S. E., Scaglione, K. M., O’Leary, J. C., Fontaine, S. N., Breydo, L., Zhang, B., Li, P., Wang, L., et al. (2013) · Journal of Clinical Investigation

Alzheimer's disease research and treatmentsHeat shock proteins research

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MicroRNA 135 is essential for chronic stress resiliency, antidepressant efficacy, and intact serotonergic activity

Issler, O., Haramati, S., Paul, E. D., Maeno, H., Navon, I., Zwang, R., Gil, S., Mayberg, H. S., Dunlop, B. W., Menke, A., et al. (2014) · Neuron

Treatment of Major DepressionMicroRNA in disease regulation

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The role of DNA methylation in stress-related psychiatric disorders

Klengel, T., Pape, J., Binder, E. B., & Mehta, D. (2014) · Neuropharmacology

Epigenetics and DNA MethylationStress Responses and Cortisol

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Epigenetic Modifications in Stress Response Genes Associated With Childhood Trauma

Jiang, S., Postovit, L., Cattaneo, A., Binder, E. B., & Aitchison, K. J. (2019) · Frontiers in Psychiatry

Child Abuse and TraumaEpigenetics and DNA Methylation

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GWAS of Suicide Attempt in Psychiatric Disorders and Association With Major Depression Polygenic Risk Scores

Mullins, N., Bigdeli, T. B., Børglum, A. D., Coleman, J. R. I., Demontis, D., Mehta, D., Power, R. A., Ripke, S., Stahl, E. A., Starnawska, A., et al. (2019) · American Journal of Psychiatry

Suicide and Self-Harm StudiesGenetic Associations and Epidemiology

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Biological embedding of experience: a primer on epigenetics

Aristizabal, M. J., Anreiter, I., Halldorsdottir, T., Odgers, C. L., McDade, T. W., Goldenberg, A., Mostafavi, S., Kobor, M. S., Binder, E. B., Sokolowski, M. B., et al. (2020) · Proceedings of the National Academy of Sciences

Epigenetics and DNA MethylationBirth, Development, and Health

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Interaction of FKBP5 Gene Variants and Adverse Life Events in Predicting Depression Onset: Results From a 10-Year Prospective Community Study

Zimmermann, P., Brückl, T., Nocon, A., Pfister, H., Binder, E. B., Uhr, M., Lieb, R., Moffitt, T. E., Caspi, A., Holsboer, F., et al. (2011) · American Journal of Psychiatry

Stress Responses and CortisolGenetic Associations and Epidemiology

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P2RX7, a gene coding for a purinergic ligand-gated ion channel, is associated with major depressive disorder

Lucae, S., Salyakina, D., Barden, N., Harvey, M., Gagné, B., Labbé, M., Binder, E. B., Uhr, M., Paez-Pereda, M., Sillaber, I., et al. (2006) · Human Molecular Genetics

Adenosine and Purinergic SignalingGenetic Associations and Epidemiology

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The effects of early life stress on the epigenome: From the womb to adulthood and even before

Provençal, N., & Binder, E. B. (2015) · Experimental Neurology

Child Abuse and TraumaEpigenetics and DNA Methylation

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Epigenetics and depression

Penner-Goeke, S., & Binder, E. B. (2019) · Dialogues in Clinical Neuroscience

Epigenetics and DNA MethylationStress Responses and Cortisol

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Selective inhibitors of the FK506-binding protein 51 by induced fit

Gaali, S., Kirschner, A., Cuboni, S., Hartmann, J., Kozany, C., Balsevich, G., Namendorf, C., Fernandez-Vizarra, P., Sippel, C., Zannas, A. S., et al. (2015) · Nature Chemical Biology

Signaling Pathways in DiseaseTreatment of Major Depression

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Genome-wide DNA methylation levels and altered cortisol stress reactivity following childhood trauma in humans

Houtepen, L. C., Vinkers, C. H., Carrillo-Roa, T., Hiemstra, M., van Lier, P. A., Meeus, W., Branje, S., Heim, C. M., Nemeroff, C. B., Mill, J., et al. (2016) · Nature Communications

Epigenetics and DNA MethylationStress Responses and Cortisol

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The Neuronal Transporter Gene SLC6A15 Confers Risk to Major Depression

Kohli, M. A., Lucae, S., Saemann, P. G., Schmidt, M. V., Demirkan, A., Hek, K., Czamara, D., Alexander, M., Salyakina, D., Ripke, S., et al. (2011) · Neuron

Genetic Associations and EpidemiologyNeurotransmitter Receptor Influence on Behavior

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Functional polymorphisms in the interleukin-6 and serotonin transporter genes, and depression and fatigue induced by interferon-α and ribavirin treatment

Bull, S. J., Huezo-Diaz, P., Binder, E. B., Cubells, J. F., Ranjith, G., Maddock, C., Miyazaki, C., Alexander, N., Hotopf, M., Cleare, A. J., et al. (2009) · Molecular Psychiatry

Tryptophan and brain disordersHepatitis C virus research

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Understanding the Molecular Mechanisms Underpinning Gene by Environment Interactions in Psychiatric Disorders: The FKBP5 Model

Matosin, N., Halldorsdottir, T., & Binder, E. B. (2018) · Biological Psychiatry

Stress Responses and CortisolGenetic Associations and Epidemiology

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Epigenetics of posttraumatic stress disorder: current evidence, challenges, and future directions

Zannas, A. S., Provençal, N., & Binder, E. B. (2015) · Biological Psychiatry

Posttraumatic Stress Disorder ResearchEpigenetics and DNA Methylation

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Association between childhood maltreatment and adult emotional dysregulation in a low-income, urban, African American sample: Moderation by oxytocin receptor gene

Bradley, B., Westen, D., Mercer, K. B., Binder, E. B., Jovanovic, T., Crain, D., Wingo, A., & Heim, C. (2011) · Development and Psychopathology

Child Abuse and TraumaNeuroendocrine regulation and behavior

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Glucocorticoid exposure during hippocampal neurogenesis primes future stress response by inducing changes in DNA methylation

Provençal, N., Arloth, J., Cattaneo, A., Anacker, C., Cattane, N., Wiechmann, T., Röh, S., Ködel, M., Klengel, T., Czamara, D., et al. (2020) · Proceedings of the National Academy of Sciences

Epigenetics and DNA MethylationStress Responses and Cortisol

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Common polymorphism in the oxytocin receptor gene ( OXTR ) is associated with human social recognition skills

Skuse, D. H., Lori, A., Cubells, J. F., Lee, I., Conneely, K. N., Puura, K., Lehtimäki, T., Binder, E. B., & Young, L. J. (2014) · Proceedings of the National Academy of Sciences

Neuroendocrine regulation and behaviorFace Recognition and Perception

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Stratified medicine for mental disorders

Schumann, G., Binder, E. B., Holte, A., de Kloet, E. R., Oedegaard, K. J., Robbins, T. W., Walker-Tilley, T. R., Bitter, I., Brown, V. J., Buitelaar, J., et al. (2014) · European Neuropsychopharmacology

Mental Health and PsychiatryMental Health Research Topics

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Charting the landscape of priority problems in psychiatry, part 1: classification and diagnosis

Stephan, K. E., Bach, D. R., Fletcher, P. C., Flint, J., Frank, M. J., Friston, K. J., Heinz, A., Huys, Q. J. M., Owen, M. J., Binder, E. B., et al. (2016) · The Lancet Psychiatry

Mental Health and PsychiatryMental Health Research Topics

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Impaired divided attention predicts delayed response and risk to relapse in subjects with depressive disorders

MAJER, M., ISING, M., KÜNZEL, H., BINDER, E. B., HOLSBOER, F., MODELL, S., & ZIHL, J. (2004) · Psychological Medicine

Treatment of Major DepressionNeural and Behavioral Psychology Studies

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Dexamethasone stimulated gene expression in peripheral blood is a sensitive marker for glucocorticoid receptor resistance in depressed patients

Menke, A., Arloth, J., Pütz, B., Weber, P., Klengel, T., Mehta, D., Gonik, M., Rex-Haffner, M., Rubel, J., Uhr, M., et al. (2012) · Neuropsychopharmacology

Stress Responses and CortisolTreatment of Major Depression

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Epigenetic alterations in depression and antidepressant treatment

Menke, A., & Binder, E. B. (2014) · Dialogues in Clinical Neuroscience

Epigenetics and DNA MethylationTreatment of Major Depression

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