Alexander, Gene E.

The Alzheimer’s disease neuroimaging initiative (ADNI): MRI methods

Jack, C. R., Bernstein, M. A., Fox, N. C., Thompson, P., Alexander, G., Harvey, D., Borowski, B., Britson, P. J., L. Whitwell, J., Ward, C., et al. (2008) · Journal of Magnetic Resonance Imaging

Dementia and Cognitive Impairment ResearchAdvanced MRI Techniques and Applications

Cited by 4,347

Functional brain abnormalities in young adults at genetic risk for late-onset Alzheimer's dementia

Reiman, E. M., Chen, K., Alexander, G. E., Caselli, R. J., Bandy, D., Osborne, D., Saunders, A. M., & Hardy, J. (2004) · Proceedings of the National Academy of Sciences

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 977

Fibrillar amyloid-β burden in cognitively normal people at 3 levels of genetic risk for Alzheimer's disease

Reiman, E. M., Chen, K., Liu, X., Bandy, D., Yu, M., Lee, W., Ayutyanont, N., Keppler, J., Reeder, S. A., Langbaum, J. B. S., et al. (2009) · Proceedings of the National Academy of Sciences

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 785

Brain imaging and fluid biomarker analysis in young adults at genetic risk for autosomal dominant Alzheimer's disease in the presenilin 1 E280A kindred: a case-control study

Reiman, E. M., Quiroz, Y. T., Fleisher, A. S., Chen, K., Velez-Pardo, C., Jimenez-Del-Rio, M., Fagan, A. M., Shah, A. R., Alvarez, S., Arbelaez, A., et al. (2012) · The Lancet Neurology

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 541

Longitudinal PET evaluation of cerebral metabolic decline in dementia: a potential outcome measure in Alzheimer’s disease treatment studies

Alexander, G. E., Chen, K., Pietrini, P., Rapoport, S. I., & Reiman, E. M. (2002) · American Journal of Psychiatry

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 532

Longitudinal Modeling of Age-Related Memory Decline and the APOE ε4 Effect

Caselli, R. J., Dueck, A. C., Osborne, D., Sabbagh, M. N., Connor, D. J., Ahern, G. L., Baxter, L. C., Rapcsak, S. Z., Shi, J., Woodruff, B. K., et al. (2009) · New England Journal of Medicine

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 528

GAB2 Alleles Modify Alzheimer's Risk in APOE ɛ4 Carriers

Reiman, E. M., Webster, J. A., Myers, A. J., Hardy, J., Dunckley, T., Zismann, V. L., Joshipura, K. D., Pearson, J. V., Hu-Lince, D., Huentelman, M. J., et al. (2007) · Neuron

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 487

Inverse relationship between education and parietotemporal perfusion deficit in Alzheimer's disease

Stern, Y., Alexander, G. E., Prohovnik, I., & Mayeux, R. (1992) · Annals of Neurology

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 470

Declining brain activity in cognitively normal apolipoprotein E ɛ4 heterozygotes: A foundation for using positron emission tomography to efficiently test treatments to prevent Alzheimer's disease

Reiman, E. M., Caselli, R. J., Chen, K., Alexander, G. E., Bandy, D., & Frost, J. (2001) · Proceedings of the National Academy of Sciences

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 467

Genome-wide association study of habitual physical activity in over 377,000 UK Biobank participants identifies multiple variants including CADM2 and APOE

Klimentidis, Y. C., Raichlen, D. A., Bea, J., Garcia, D. O., Wineinger, N. E., Mandarino, L. J., Alexander, G. E., Chen, Z., & Going, S. B. (2018) · International Journal of Obesity

Genetics and Physical PerformanceGenetic Associations and Epidemiology

Cited by 403

Correlations between apolipoprotein E ε4 gene dose and brain-imaging measurements of regional hypometabolism

Reiman, E. M., Chen, K., Alexander, G. E., Caselli, R. J., Bandy, D., Osborne, D., Saunders, A. M., & Hardy, J. (2005) · Proceedings of the National Academy of Sciences

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 401

Detailed comparison of amyloid PET and CSF biomarkers for identifying early Alzheimer disease

Palmqvist, S., Zetterberg, H., Mattsson, N., Johansson, P., Initiative, F. T. A. D. N., Minthon, L., Blennow, K., Olsson, M., For the Swedish BioFINDER study group, Hansson, O., et al. (2015) · Neurology

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 375

Association of premorbid intellectual function with cerebral metabolism in Alzheimer's disease: implications for the cognitive reserve hypothesis

Alexander, G. E., Furey, M. L., Grady, C. L., Pietrini, P., Brady, D. R., Mentis, M. J., & Schapiro, M. B. (1997) · American Journal of Psychiatry

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 327

Categorical and correlational analyses of baseline fluorodeoxyglucose positron emission tomography images from the Alzheimer’s Disease Neuroimaging Initiative (ADNI)

Langbaum, J. B. S., Chen, K., Lee, W., Reschke, C., Bandy, D., Fleisher, A. S., Alexander, G. E., Foster, N. L., Weiner, M. W., Koeppe, R. A., et al. (2009) · NeuroImage

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 279

The metabolic topography of normal aging

Moeller, J. R., Ishikawa, T., Dhawan, V., Spetsieris, P., Mandel, F., Alexander, G. E., Grady, C., Pietrini, P., & Eidelberg, D. (1996) · Journal of Cerebral Blood Flow & Metabolism

Dementia and Cognitive Impairment ResearchFunctional Brain Connectivity Studies

Cited by 254

Apolipoprotein E (APOE) genotype has dissociable effects on memory and attentional–executive network function in Alzheimer’s disease

Wolk, D. A., Dickerson, B. C., Initiative, T. A. D. N., Weiner, M., Aiello, M., Aisen, P., Albert, M. S., Alexander, G., Anderson, H. S., Anderson, K., et al. (2010) · Proceedings of the National Academy of Sciences

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 248

Subregional neuroanatomical change as a biomarker for Alzheimer's disease

Holland, D., Brewer, J. B., Hagler, D. J., Fennema-Notestine, C., Dale, A. M., Initiative, T. A. D. N., Weiner, M., Thal, L., Petersen, R., Jack, C. R., et al. (2009) · Proceedings of the National Academy of Sciences

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 210

Progression of corpus callosum atrophy in Alzheimer disease

Teipel, S. J., Bayer, W., Alexander, G. E., Zebuhr, Y., Teichberg, D., Kulic, L., Schapiro, M. B., Möller, H.-J., Rapoport, S. I., & Hampel, H. (2002) · Archives of Neurology

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 202

Alzheimer's Disease Neuroimaging Initiative: A one-year follow up study using tensor-based morphometry correlating degenerative rates, biomarkers and cognition

Leow, A. D., Yanovsky, I., Parikshak, N., Hua, X., Lee, S., Toga, A. W., Jack, C. R., Bernstein, M. A., Britson, P. J., Gunter, J. L., et al. (2009) · NeuroImage

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 180

Posterior Cingulate Glucose Metabolism, Hippocampal Glucose Metabolism, and Hippocampal Volume in Cognitively Normal, Late-Middle-Aged Persons at 3 Levels of Genetic Risk for Alzheimer Disease

Protas, H. D., Chen, K., Langbaum, J. B. S., Fleisher, A. S., Alexander, G. E., Lee, W., Bandy, D., de Leon, M. J., Mosconi, L., Buckley, S., et al. (2013) · JAMA Neurology

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 161

Impaired platelet mitochondrial activity in Alzheimer's disease and mild cognitive impairment

Valla, J., Schneider, L., Niedzielko, T., Coon, K. D., Caselli, R., Sabbagh, M. N., Ahern, G. L., Baxter, L., Alexander, G., Walker, D. G., et al. (2006) · Mitochondrion

Mitochondrial Function and PathologyAlzheimer's disease research and treatments

Cited by 159

Sedentary Behavior and Incident Dementia Among Older Adults

Raichlen, D. A., Aslan, D. H., Sayre, M. K., Bharadwaj, P. K., Ally, M., Maltagliati, S., Lai, M. H. C., Wilcox, R. R., Klimentidis, Y. C., & Alexander, G. E. (2023) · JAMA

Physical Activity and HealthDementia and Cognitive Impairment Research

Cited by 156

Optimizing power to track brain degeneration in Alzheimer’s disease and mild cognitive impairment with tensor-based morphometry: an ADNI study of 515 subjects

Hua, X., Lee, S., Yanovsky, I., Leow, A. D., Chou, Y.-Y., Ho, A. J., Gutman, B., Toga, A. W., Jack, C. R., Bernstein, M. A., et al. (2009) · NeuroImage

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 145

Mild cognitive impairment with suspected nonamyloid pathology (SNAP): Prediction of progression

Caroli, A., Prestia, A., Galluzzi, S., Ferrari, C., van der Flier, W. M., Ossenkoppele, R., Van Berckel, B., Barkhof, F., Teunissen, C., Wall, A. E., et al. (2015) · Neurology

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