Holloway, Graham P.

Repeated transient mRNA bursts precede increases in transcriptional and mitochondrial proteins during training in human skeletal muscle: Molecular responses during mitochondrial biogenesis

Perry, C. G. R., Lally, J., Holloway, G. P., Heigenhauser, G. J. F., Bonen, A., & Spriet, L. L. (2010) · The Journal of Physiology

Adipose Tissue and MetabolismCardiovascular and exercise physiology

Cited by 559

One Week of Bed Rest Leads to Substantial Muscle Atrophy and Induces Whole-Body Insulin Resistance in the Absence of Skeletal Muscle Lipid Accumulation

Dirks, M. L., Wall, B. T., van de Valk, B., Holloway, T. M., Holloway, G. P., Chabowski, A., Goossens, G. H., & van Loon, L. J. C. (2016) · Diabetes

Spaceflight effects on biologyMuscle Physiology and Disorders

Cited by 391

AMPK regulation of fatty acid metabolism and mitochondrial biogenesis: implications for obesity.

O’Neill, H. M., Holloway, G. P., & Steinberg, G. R. (2013) · Molecular and Cellular Endocrinology

Metabolism, Diabetes, and CancerAdipose Tissue and Metabolism

Cited by 364

Modest PGC-1α Overexpression in Muscle in Vivo Is Sufficient to Increase Insulin Sensitivity and Palmitate Oxidation in Subsarcolemmal, Not Intermyofibrillar, Mitochondria

Benton, C. R., Nickerson, J. G., Lally, J., Han, X.-X., Holloway, G. P., Glatz, J. F. C., Luiken, J. J. F. P., Graham, T. E., Heikkila, J. J., & Bonen, A. (2008) · Journal of Biological Chemistry

Adipose Tissue and MetabolismMetabolism, Diabetes, and Cancer

Cited by 214

Omega-3 supplementation alters mitochondrial membrane composition and respiration kinetics in human skeletal muscle

Herbst, E. A. F., Paglialunga, S., Gerling, C., Whitfield, J., Mukai, K., Chabowski, A., Heigenhauser, G. J. F., Spriet, L. L., & Holloway, G. P. (2014) · The Journal of Physiology

Fatty Acid Research and HealthMitochondrial Function and Pathology

Cited by 179

Exercise training increases sarcolemmal and mitochondrial fatty acid transport proteins in human skeletal muscle

Talanian, J. L., Holloway, G. P., Snook, L. A., Heigenhauser, G. J. F., Bonen, A., & Spriet, L. L. (2010) · American Journal of Physiology-Endocrinology and Metabolism

Adipose Tissue and MetabolismCardiovascular and exercise physiology

Cited by 167

Skeletal muscle mitochondrial FAT/CD36 content and palmitate oxidation are not decreased in obese women.

Holloway, G. P., Thrush, A. B., Heigenhauser, G. J. F., Tandon, N. N., Dyck, D. J., Bonen, A., & Spriet, L. L. (2007) · American Journal of Physiology-Endocrinology and Metabolism

Adipose Tissue and MetabolismMitochondrial Function and Pathology

Cited by 147

Age-Associated Impairments in Mitochondrial ADP Sensitivity Contribute to Redox Stress in Senescent Human Skeletal Muscle

Holloway, G. P., Holwerda, A. M., Miotto, P. M., Dirks, M. L., Verdijk, L. B., & van Loon, L. J. C. (2018) · Cell Reports

Mitochondrial Function and PathologyExercise and Physiological Responses

Cited by 134

Beetroot juice supplementation reduces whole body oxygen consumption but does not improve indices of mitochondrial efficiency in human skeletal muscle

Whitfield, J., Ludzki, A., Heigenhauser, G. J. F., Senden, J. M. G., Verdijk, L. B., van Loon, L. J. C., Spriet, L. L., & Holloway, G. P. (2016) · The Journal of Physiology

Cardiovascular and exercise physiologyExercise and Physiological Responses

Cited by 115

Beetroot Juice Increases Human Muscle Force without Changing Ca2+-Handling Proteins

WHITFIELD, J., GAMU, D., HEIGENHAUSER, G. J. F., VAN LOON, L. J. C., SPRIET, L. L., TUPLING, A. R., & HOLLOWAY, G. P. (2017) · Medicine & Science in Sports & Exercise

Cardiovascular and exercise physiologyMuscle metabolism and nutrition

Cited by 83

Compensatory increases in nuclear PGC1α protein are primarily associated with subsarcolemmal mitochondrial adaptations in ZDF rats.

Holloway, G. P., Gurd, B. J., Snook, L. A., Lally, J., & Bonen, A. (2010) · Diabetes

Adipose Tissue and MetabolismPeroxisome Proliferator-Activated Receptors

Cited by 55

Increasing skeletal muscle fatty acid transport protein 1 (FATP1) targets fatty acids to oxidation and does not predispose mice to diet-induced insulin resistance

Holloway, G. P., Chou, C. J., Lally, J., Stellingwerff, T., Maher, A. C., Gavrilova, O., Haluzik, M., Alkhateeb, H., Reitman, M. L., & Bonen, A. (2011) · Diabetologia

Metabolism, Diabetes, and CancerAdipose Tissue and Metabolism

Cited by 54

Are Alterations in Skeletal Muscle Mitochondria a Cause or Consequence of Insulin Resistance?

Genders, A. J., Holloway, G. P., & Bishop, D. J. (2020) · International Journal of Molecular Sciences

Metabolism, Diabetes, and CancerMitochondrial Function and Pathology

Cited by 51

Both linoleic and α-linolenic acid prevent insulin resistance but have divergent impacts on skeletal muscle mitochondrial bioenergetics in obese Zucker rats

Matravadia, S., Herbst, E. A. F., Jain, S. S., Mutch, D. M., & Holloway, G. P. (2014) · American Journal of Physiology-Endocrinology and Metabolism

Fatty Acid Research and HealthAdipose Tissue and Metabolism

Cited by 46

Insights into the development of insulin resistance: Unraveling the interaction of physical inactivity, lipid metabolism and mitochondrial biology

Handy, R. M., & Holloway, G. P. (2023) · Frontiers in Physiology

Metabolism, Diabetes, and CancerAdipose Tissue and Metabolism

Cited by 38

A decreased n-6/n-3 ratio in the fat-1 mouse is associated with improved glucose tolerance

Smith, B. K., Holloway, G. P., Reza-Lopez, S., Jeram, S. M., Kang, J. X., & Ma, D. W. L. (2010) · Applied Physiology Nutrition and Metabolism

Fatty Acid Research and HealthAdipose Tissue and Metabolism

Cited by 35

Exercise-induced reductions in mitochondrial ADP sensitivity contribute to the induction of gene expression and mitochondrial biogenesis through enhanced mitochondrial H2O2 emission

Miotto, P. M., & Holloway, G. P. (2019) · Mitochondrion

Mitochondrial Function and PathologyExercise and Physiological Responses

Cited by 30

Activation of AMPKα2 Is Not Required for Mitochondrial FAT/CD36 Accumulation during Exercise

Monaco, C., Whitfield, J., Jain, S. S., Spriet, L. L., Bonen, A., & Holloway, G. P. (2015) · PLOS ONE

Metabolism, Diabetes, and CancerAdipose Tissue and Metabolism

Cited by 27

Over-Expressing Mitofusin-2 in Healthy Mature Mammalian Skeletal Muscle Does Not Alter Mitochondrial Bioenergetics

Lally, J. S. V., Herbst, E. A. F., Matravadia, S., Maher, A. C., Perry, C. G. R., Ventura-Clapier, R., & Holloway, G. P. (2013) · PLoS ONE

Mitochondrial Function and PathologyMuscle Physiology and Disorders

Cited by 19

Glucose-dependent insulinotropic polypeptide directly induces glucose transport in rat skeletal muscle

Snook, L. A., Nelson, E. M., Dyck, D. J., Wright, D. C., & Holloway, G. P. (2015) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology

Metabolism, Diabetes, and CancerDiabetes Treatment and Management

Cited by 17

Fatiguing high-intensity intermittent exercise depresses maximal Na+-K+-ATPase activity in human skeletal muscle assessed using a novel NADH-coupled assay

Vigh-Larsen, J. F., Frangos, S. M., Overgaard, K., Holloway, G. P., & Mohr, M. (2025) · Pflügers Archiv - European Journal of Physiology

Cardiovascular and exercise physiologyExercise and Physiological Responses

Cited by 6