Hannon, Eilis

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

eQTLGen, Wray, N. R., 23andMe, the Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Adams, M. J., et al. (2018) · Nature Genetics

Genetic Associations and EpidemiologyTreatment of Major Depression

Cited by 3,005

De novo mutations in schizophrenia implicate synaptic networks

Fromer, M., Pocklington, A. J., Kavanagh, D. H., Williams, H. J., Dwyer, S., Gormley, P., Georgieva, L., Rees, E., Palta, P., Ruderfer, D. M., et al. (2014) · Nature

Schizophrenia research and treatmentGenetics and Neurodevelopmental Disorders

Cited by 1,617

DunedinPACE, a DNA methylation biomarker of the pace of aging

Belsky, D. W., Caspi, A., Corcoran, D. L., Sugden, K., Poulton, R., Arseneault, L., Baccarelli, A., Chamarti, K., Gao, X., Hannon, E., et al. (2022) · eLife

Epigenetics and DNA MethylationGenetics, Aging, and Longevity in Model Organisms

Cited by 1,083

Association of Lifestyle and Genetic Risk With Incidence of Dementia

Lourida, I., Hannon, E., Littlejohns, T. J., Langa, K. M., Hyppönen, E., Kuzma, E., & Llewellyn, D. J. (2019) · JAMA

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 881

Methylomic profiling implicates cortical deregulation of ANK1 in Alzheimer's disease

Lunnon, K., Smith, R., Hannon, E., De Jager, P. L., Srivastava, G., Volta, M., Troakes, C., Al-Sarraj, S., Burrage, J., Macdonald, R., et al. (2014) · Nature Neuroscience

Epigenetics and DNA MethylationAlzheimer's disease research and treatments

Cited by 574

Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology

van Rheenen, W., van der Spek, R. A. A., Bakker, M. K., van Vugt, J. J. F. A., Hop, P. J., Zwamborn, R. A. J., de Klein, N., Westra, H.-J., Bakker, O. B., Deelen, P., et al. (2021) · Nature Genetics

Amyotrophic Lateral Sclerosis ResearchGenetic Associations and Epidemiology

Cited by 542

Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation

Min, J. L., Hemani, G., Hannon, E., Dekkers, K. F., Castillo-Fernandez, J., Luijk, R., Carnero-Montoro, E., Lawson, D. J., Burrows, K., Suderman, M., et al. (2021) · Nature Genetics

Epigenetics and DNA MethylationGenetic Associations and Epidemiology

Cited by 506

Interindividual methylomic variation across blood, cortex, and cerebellum: implications for epigenetic studies of neurological and neuropsychiatric phenotypes

Hannon, E., Lunnon, K., Schalkwyk, L., & Mill, J. (2015) · Epigenetics

Epigenetics and DNA MethylationGenetic Associations and Epidemiology

Cited by 455

An integrated genetic-epigenetic analysis of schizophrenia: evidence for co-localization of genetic associations and differential DNA methylation

Hannon, E., Dempster, E., Viana, J., Burrage, J., Smith, A. R., Macdonald, R., St Clair, D., Mustard, C., Breen, G., Therman, S., et al. (2016) · Genome Biology

Epigenetics and DNA MethylationSchizophrenia research and treatment

Cited by 349

Guidance for DNA methylation studies: statistical insights from the Illumina EPIC array

Mansell, G., Gorrie-Stone, T. J., Bao, Y., Kumari, M., Schalkwyk, L. S., Mill, J., & Hannon, E. (2019) · BMC Genomics

Epigenetics and DNA MethylationGenetic Associations and Epidemiology

Cited by 340

Methylomic trajectories across human fetal brain development

Spiers, H., Hannon, E., Schalkwyk, L. C., Smith, R., Wong, C. C. Y., O’Donovan, M. C., Bray, N. J., & Mill, J. (2015) · Genome Research

Epigenetics and DNA MethylationGenetic Syndromes and Imprinting

Cited by 287

A histone acetylome-wide association study of Alzheimer’s disease identifies disease-associated H3K27ac differences in the entorhinal cortex

Marzi, S. J., Leung, S. K., Ribarska, T., Hannon, E., Smith, A. R., Pishva, E., Poschmann, J., Moore, K., Troakes, C., Al-Sarraj, S., et al. (2018) · Nature Neuroscience

Alzheimer's disease research and treatmentsGenomics and Chromatin Dynamics

Cited by 232

Elevated DNA methylation across a 48‐kb region spanning the HOXA gene cluster is associated with Alzheimer's disease neuropathology

Smith, R. G., Hannon, E., De Jager, P. L., Chibnik, L., Lott, S. J., Condliffe, D., Smith, A. R., Haroutunian, V., Troakes, C., Al‐Sarraj, S., et al. (2018) · Alzheimer's & Dementia

Epigenetics and DNA MethylationDementia and Cognitive Impairment Research

Cited by 184

Analysis of DNA methylation in young people: limited evidence for an association between victimization stress and epigenetic variation in blood

Marzi, S. J., Sugden, K., Arseneault, L., Belsky, D. W., Burrage, J., Corcoran, D. L., Danese, A., Fisher, H. L., Hannon, E., Moffitt, T. E., et al. (2018) · American Journal of Psychiatry

Child Abuse and TraumaEpigenetics and DNA Methylation

Cited by 163

Methylomic profiling of human brain tissue supports a neurodevelopmental origin for schizophrenia

Pidsley, R., Viana, J., Hannon, E., Spiers, H., Troakes, C., Al-Saraj, S., Mechawar, N., Turecki, G., Schalkwyk, L. C., Bray, N. J., et al. (2014) · Genome biology

Epigenetics and DNA MethylationSchizophrenia research and treatment

Cited by 157

Patterns of Reliability: Assessing the Reproducibility and Integrity of DNA Methylation Measurement

Sugden, K., Hannon, E. J., Arseneault, L., Belsky, D. W., Corcoran, D. L., Fisher, H. L., Houts, R. M., Kandaswamy, R., Moffitt, T. E., Poulton, R., et al. (2020) · Patterns

Epigenetics and DNA MethylationGene expression and cancer classification

Cited by 151

DNA methylation meta-analysis reveals cellular alterations in psychosis and markers of treatment-resistant schizophrenia

Hannon, E., Dempster, E. L., Mansell, G., Burrage, J., Bass, N., Bohlken, M. M., Corvin, A., Curtis, C. J., Dempster, D., Di Forti, M., et al. (2021) · eLife

Epigenetics and DNA MethylationSchizophrenia research and treatment

Cited by 132

Schizophrenia-associated methylomic variation: molecular signatures of disease and polygenic risk burden across multiple brain regions

Viana, J., Hannon, E., Dempster, E., Pidsley, R., Macdonald, R., Knox, O., Spiers, H., Troakes, C., Al-Saraj, S., Turecki, G., et al. (2016) · Human Molecular Genetics

Epigenetics and DNA MethylationSchizophrenia research and treatment

Cited by 105

Meta-analysis of genome-wide DNA methylation identifies shared associations across neurodegenerative disorders

study, T. A. I. B. A. L., Nabais, M. F., Initiative, T. A. D. N., Laws, S. M., Lin, T., Vallerga, C. L., Armstrong, N. J., Blair, I. P., Kwok, J. B., Mather, K. A., et al. (2021) · Genome Biology

Epigenetics and DNA MethylationDementia and Cognitive Impairment Research

Cited by 99

Genome-wide DNA methylation profiling identifies convergent molecular signatures associated with idiopathic and syndromic autism in post-mortem human brain tissue

Wong, C. C. Y., Smith, R. G., Hannon, E., Ramaswami, G., Parikshak, N. N., Assary, E., Troakes, C., Poschmann, J., Schalkwyk, L. C., Sun, W., et al. (2019) · Human Molecular Genetics

Autism Spectrum Disorder ResearchGenetics and Neurodevelopmental Disorders

Cited by 98

An epigenome-wide association study of Alzheimer's disease blood highlights robust DNA hypermethylation in the HOXB6 gene

Roubroeks, J. A. Y., Smith, A. R., Smith, R. G., Pishva, E., Ibrahim, Z., Sattlecker, M., Hannon, E. J., Kłoszewska, I., Mecocci, P., Soininen, H., et al. (2020) · Neurobiology of Aging

Epigenetics and DNA MethylationDementia and Cognitive Impairment Research

Cited by 82

5-hydroxymethylcytosine is highly dynamic across human fetal brain development

Spiers, H., Hannon, E., Schalkwyk, L. C., Bray, N. J., & Mill, J. (2017) · BMC Genomics

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 80

Transcriptional signatures of tau and amyloid neuropathology

Castanho, I., Murray, T. K., Hannon, E., Jeffries, A., Walker, E., Laing, E., Baulf, H., Harvey, J., Bradshaw, L., Randall, A., et al. (2020) · Cell Reports

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 62

Genome-wide DNA methylation meta-analysis in the brains of suicide completers

Policicchio, S., Washer, S., Viana, J., Iatrou, A., Burrage, J., Hannon, E., Turecki, G., Kaminsky, Z., Mill, J., Dempster, E. L., et al. (2020) · Translational Psychiatry

Epigenetics and DNA MethylationSuicide and Self-Harm Studies

Cited by 61