Magnuson, Mark A.

Dual Roles for Glucokinase in Glucose Homeostasis as Determined by Liver and Pancreatic β Cell-specific Gene Knock-outs Using Cre Recombinase

Postic, C., Shiota, M., Niswender, K. D., Jetton, T. L., Chen, Y., Moates, J. M., Shelton, K. D., Lindner, J., Cherrington, A. D., & Magnuson, M. A. (1999) · Journal of Biological Chemistry

Pancreatic function and diabetesMetabolism, Diabetes, and Cancer

Cited by 1,302

Loss of insulin signaling in hepatocytes leads to severe insulin resistance and progressive hepatic dysfunction.

Michael, M. D., Kulkarni, R. N., Postic, C., Previs, S. F., Shulman, G. I., Magnuson, M. A., & Kahn, C. R. (2000) · Molecular Cell

Metabolism, Diabetes, and CancerPancreatic function and diabetes

Cited by 1,296

Thiazolidinediones expand body fluid volume through PPARγ stimulation of ENaC-mediated renal salt absorption

Guan, Y., Hao, C., Cha, D. R., Rao, R., Lu, W., Kohan, D. E., Magnuson, M. A., Redha, R., Zhang, Y., & Breyer, M. D. (2005) · Nature Medicine

Peroxisome Proliferator-Activated ReceptorsIon Transport and Channel Regulation

Cited by 608

Liver-specific deletion of negative regulator Pten results in fatty liver and insulin hypersensitivity

Stiles, B., Wang, Y., Stahl, A., Bassilian, S., Lee, W. P., Kim, Y.-J., Sherwin, R., Devaskar, S., Lesche, R., Magnuson, M. A., et al. (2004) · Proceedings of the National Academy of Sciences

Metabolism, Diabetes, and CancerLiver Disease Diagnosis and Treatment

Cited by 436

Impaired insulin secretion and β-cell loss in tissue-specific knockout mice with mitochondrial diabetes

Silva, J. P., Köhler, M., Graff, C., Oldfors, A., Magnuson, M. A., Berggren, P.-O., & Larsson, N.-G. (2000) · Nature Genetics

Pancreatic function and diabetesMitochondrial Function and Pathology

Cited by 433

p16Ink4a-induced senescence of pancreatic beta cells enhances insulin secretion

Helman, A., Klochendler, A., Azazmeh, N., Gabai, Y., Horwitz, E., Anzi, S., Swisa, A., Condiotti, R., Granit, R. Z., Nevo, Y., et al. (2016) · Nature Medicine

Pancreatic function and diabetesTelomeres, Telomerase, and Senescence

Cited by 351

Inactivation of the hepatic cytochrome P450 system by conditional deletion of hepatic cytochrome P450 reductase

Henderson, C. J., Otto, D. M. E., Carrie, D., Magnuson, M. A., McLaren, A. W., Rosewell, I., & Wolf, C. R. (2003) · Journal of Biological Chemistry

Pharmacogenetics and Drug MetabolismDrug-Induced Hepatotoxicity and Protection

Cited by 258

Impaired insulin secretion and glucose tolerance in β cell‐selective CaV1.2 Ca2+ channel null mice

Schulla, V., Renström, E., Feil, R., Feil, S., Franklin, I., Gjinovci, A., Jing, X., Laux, D., Lundquist, I., Magnuson, M. A., et al. (2003) · The EMBO Journal

Pancreatic function and diabetesIon channel regulation and function

Cited by 234

Targeted disruption of hepatic frataxin expression causes impaired mitochondrial function, decreased life span and tumor growth in mice

Thierbach, R., Schulz, T. J., Isken, F., Voigt, A., Mietzner, B., Drewes, G., von Kleist-Retzow, J.-C., Wiesner, R. J., Magnuson, M. A., Puccio, H., et al. (2005) · Human Molecular Genetics

Mitochondrial Function and PathologyMetabolism, Diabetes, and Cancer

Cited by 127

Genetic rescue of Cdk4 null mice restores pancreatic β-cell proliferation but not homeostatic cell number

Martín, J., Hunt, S. L., Dubus, P., Sotillo, R., Néhmé-Pélluard, F., Magnuson, M. A., Parlow, A. F., Malumbres, M., Ortega, S., & Barbacid, M. (2003) · Oncogene

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 122

Insights into the Structure and Regulation of Glucokinase from a Novel Mutation (V62M), Which Causes Maturity-onset Diabetes of the Young

Gloyn, A. L., Odili, S., Zelent, D., Buettger, C., Castleden, H. A. J., Steele, A. M., Stride, A., Shiota, C., Magnuson, M. A., Lorini, R., et al. (2005) · Journal of Biological Chemistry

Pancreatic function and diabetesGlycogen Storage Diseases and Myoclonus

Cited by 108

The histone demethylase Jmjd3 sequentially associates with the transcription factors Tbx3 and Eomes to drive endoderm differentiation

Kartikasari, A. E. R., Zhou, J. X., Kanji, M. S., Chan, D. N., Sinha, A., Grapin‐Botton, A., Magnuson, M. A., Lowry, W. E., & Bhushan, A. (2013) · The EMBO Journal

Pluripotent Stem Cells ResearchGenomics and Chromatin Dynamics

Cited by 90

Energy Homeostasis and Gastrointestinal Endocrine Differentiation Do Not Require the Anorectic Hormone Peptide YY

Schonhoff, S., Baggio, L., Ratineau, C., Ray, S. K., Lindner, J., Magnuson, M. A., Drucker, D. J., & Leiter, A. B. (2005) · Molecular and Cellular Biology

Pancreatic function and diabetesRegulation of Appetite and Obesity

Cited by 53

Impaired glucagon secretory responses in mice lacking the type 1 sulfonylurea receptor

Shiota, C., Rocheleau, J. V., Shiota, M., Piston, D. W., & Magnuson, M. A. (2005) · American Journal of Physiology-Endocrinology and Metabolism

Pancreatic function and diabetesIon channel regulation and function

Cited by 44