Cocco, Lucio

Multiple roles of phosphoinositide-specific phospholipase C isozymes

Suh, P.-G., Park, J.-I., Manzoli, L., Cocco, L., Peak, J. C., Katan, M., Fukami, K., Kataoka, T., Yun, S.-U., & Ryu, S.-H. (2008) · BMB Reports

Protein Kinase Regulation and GTPase SignalingPI3K/AKT/mTOR signaling in cancer

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Targeting GSK3 and Associated Signaling Pathways Involved in Cancer

Duda, P., Akula, S. M., Abrams, S. L., Steelman, L. S., Martelli, A. M., Cocco, L., Ratti, S., Candido, S., Libra, M., Montalto, G., et al. (2020) · Cells

Wnt/β-catenin signaling in development and cancerPI3K/AKT/mTOR signaling in cancer

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Phosphoinositide-specific phospholipase C in health and disease

Cocco, L., Follo, M. Y., Manzoli, L., & Suh, P.-G. (2015) · Journal of Lipid Research

Protein Kinase Regulation and GTPase SignalingPI3K/AKT/mTOR signaling in cancer

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Forebrain-specific ablation of phospholipase Cγ1 causes manic-like behavior

Yang, Y. R., Jung, J. H., Kim, S.-J., Hamada, K., Suzuki, A., Kim, H. J., Lee, J. H., Kwon, O.-B., Lee, Y. K., Kim, J., et al. (2017) · Molecular Psychiatry

Bipolar Disorder and TreatmentNeuroscience and Neuropharmacology Research

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Effects of TP53 Mutations and miRs on Immune Responses in the Tumor Microenvironment Important in Pancreatic Cancer Progression

McCubrey, J. A., Yang, L. V., Abrams, S. L., Steelman, L. S., Follo, M. Y., Cocco, L., Ratti, S., Martelli, A. M., Augello, G., & Cervello, M. (2022) · Cells

Pancreatic and Hepatic Oncology ResearchMicroRNA in disease regulation

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Response of high-risk MDS to azacitidine and lenalidomide is impacted by baseline and acquired mutations in a cluster of three inositide-specific genes

Follo, M. Y., Pellagatti, A., Armstrong, R. N., Ratti, S., Mongiorgi, S., De Fanti, S., Bochicchio, M. T., Russo, D., Gobbi, M., Miglino, M., et al. (2019) · Leukemia

Acute Myeloid Leukemia ResearchRetinoids in leukemia and cellular processes

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Introduction of WT-TP53 into pancreatic cancer cells alters sensitivity to chemotherapeutic drugs, targeted therapeutics and nutraceuticals

Abrams, S. L., Lertpiriyapong, K., Yang, L. V., Martelli, A. M., Cocco, L., Ratti, S., Falasca, M., Murata, R. M., Rosalen, P. L., Lombardi, P., et al. (2018) · Advances in Biological Regulation

Pancreatic and Hepatic Oncology ResearchCancer-related Molecular Pathways

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Phospholipase C‐β1 potentiates glucose‐stimulated insulin secretion

Hwang, H.-J., Yang, Y. R., Kim, H. Y., Choi, Y., Park, K.-S., Lee, H., Ma, J. S., Yamamoto, M., Kim, J., Chae, Y. C., et al. (2019) · The FASEB Journal

Pancreatic function and diabetesDiabetes Treatment and Management

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Wild type and gain of function mutant TP53 can regulate the sensitivity of pancreatic cancer cells to chemotherapeutic drugs, EGFR/Ras/Raf/MEK, and PI3K/mTORC1/GSK-3 pathway inhibitors, nutraceuticals and alter metabolic properties

McCubrey, J. A., Meher, A. K., Akula, S. M., Abrams, S. L., Steelman, L. S., LaHair, M. M., Franklin, R. A., Martelli, A. M., Ratti, S., Cocco, L., et al. (2022) · Aging

Cancer-related Molecular PathwaysPancreatic and Hepatic Oncology Research

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The regulation of insulin secretion via phosphoinositide-specific phospholipase Cβ signaling

Hwang, H.-J., Jang, H.-J., Cocco, L., & Suh, P.-G. (2019) · Advances in Biological Regulation

Pancreatic function and diabetesProtein Kinase Regulation and GTPase Signaling

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