Chelko, Stephen P.

Therapeutic Modulation of the Immune Response in Arrhythmogenic Cardiomyopathy

Chelko, S. P., Asimaki, A., Lowenthal, J., Bueno-Beti, C., Bedja, D., Scalco, A., Amat-Alarcon, N., Andersen, P., Judge, D. P., Tung, L., et al. (2019) · Circulation

Cardiovascular Effects of ExerciseCardiomyopathy and Myosin Studies

Cited by 192

Central role for GSK3β in the pathogenesis of arrhythmogenic cardiomyopathy

Chelko, S. P., Asimaki, A., Andersen, P., Bedja, D., Amat-Alarcon, N., DeMazumder, D., Jasti, R., MacRae, C. A., Leber, R., Kleber, A. G., et al. (2016) · JCI Insight

Cardiovascular Effects of ExerciseCardiomyopathy and Myosin Studies

Cited by 180

Precardiac organoids form two heart fields via Bmp/Wnt signaling

Andersen, P., Tampakakis, E., Jimenez, D. V., Kannan, S., Miyamoto, M., Shin, H. K., Saberi, A., Murphy, S., Sulistio, E., Chelko, S. P., et al. (2018) · Nature Communications

Congenital heart defects researchPluripotent Stem Cells Research

Cited by 132

Exercise triggers CAPN1-mediated AIF truncation, inducing myocyte cell death in arrhythmogenic cardiomyopathy

Chelko, S. P., Keceli, G., Carpi, A., Doti, N., Agrimi, J., Asimaki, A., Beti, C. B., Miyamoto, M., Amat-Codina, N., Bedja, D., et al. (2021) · Science Translational Medicine

Cardiac electrophysiology and arrhythmiasCardiovascular Effects of Exercise

Cited by 92

Arrhythmogenic Right Ventricular Cardiomyopathy Presenting as Clinical Myocarditis in Women

Scheel, P. J., Murray, B., Tichnell, C., James, C. A., Tandri, H., Calkins, H., Chelko, S. P., & Gilotra, N. A. (2021) · The American Journal of Cardiology

Cardiovascular Effects of ExerciseViral Infections and Immunology Research

Cited by 62

Altered Electrical, Biomolecular, and Immunologic Phenotypes in a Novel Patient-Derived Stem Cell Model of Desmoglein-2 Mutant ARVC

Hawthorne, R. N., Blazeski, A., Lowenthal, J., Kannan, S., Teuben, R., DiSilvestre, D., Morrissette-McAlmon, J., Saffitz, J. E., Boheler, K. R., James, C. A., et al. (2021) · Journal of Clinical Medicine

Cardiovascular Effects of ExerciseCardiac electrophysiology and arrhythmias

Cited by 41

NFĸB signaling drives myocardial injury via CCR2+ macrophages in a preclinical model of arrhythmogenic cardiomyopathy

Chelko, S. P., Penna, V. R., Engel, M., Shiel, E. A., Centner, A. M., Farra, W., Cannon, E. N., Landim-Vieira, M., Schaible, N., Lavine, K., et al. (2024) · Journal of Clinical Investigation

Cardiac electrophysiology and arrhythmiasCardiovascular Effects of Exercise

Cited by 32

Psychosocial Stress Hastens Disease Progression and Sudden Death in Mice with Arrhythmogenic Cardiomyopathy

Agrimi, J., Scalco, A., Agafonova, J., Williams III, L., Pansari, N., Keceli, G., Jun, S., Wang, N., Mastorci, F., Tichnell, C., et al. (2020) · Journal of Clinical Medicine

Cardiovascular Effects of ExerciseCardiac electrophysiology and arrhythmias

Cited by 29

Cardiac sympathetic neurons are additional cells affected in genetically determined arrhythmogenic cardiomyopathy

Vanaja, I. P., Scalco, A., Ronfini, M., Bona, A. D., Olianti, C., Rizzo, S., Chelko, S. P., Corrado, D., Sacconi, L., Basso, C., et al. (2025) · The Journal of Physiology

Cardiovascular Effects of ExerciseCardiac electrophysiology and arrhythmias

Cited by 17

Arrhythmogenic Cardiomyopathy Is a Multicellular Disease Affecting Cardiac and Bone Marrow Mesenchymal Stromal Cells

Scalco, A., Liboni, C., Angioni, R., Di Bona, A., Albiero, M., Bertoldi, N., Fadini, G. P., Thiene, G., Chelko, S. P., Basso, C., et al. (2021) · Journal of Clinical Medicine

Cardiovascular Effects of ExerciseCardiomyopathy and Myosin Studies

Cited by 15

High-Fat Diet Augments Myocardial Inflammation and Cardiac Dysfunction in Arrhythmogenic Cardiomyopathy

Centner, A. M., Shiel, E. A., Farra, W., Cannon, E. N., Landim-Vieira, M., Salazar, G., & Chelko, S. P. (2024) · Nutrients

Cardiovascular Effects of ExerciseCardiomyopathy and Myosin Studies

Cited by 8

Efficacy and Safety of Angiotensin Receptor Blockers in a Pre-Clinical Model of Arrhythmogenic Cardiomyopathy

Landim-Vieira, M., Kahmini, A. R., Engel, M., Cannon, E. N., Amat-Alarcon, N., Judge, D. P., Pinto, J. R., & Chelko, S. P. (2022) · International Journal of Molecular Sciences

Cardiovascular Effects of ExerciseCardiac electrophysiology and arrhythmias

Cited by 7

Evaluation of Tideglusib as a Disease Modifying Therapy in Murine Models of Arrhythmogenic Cardiomyopathy

Malhotra, N., Cavus, O., Wallace, M. J., Bobik, J. T., You, K., Takenaka, S. S., Abdallah, D., Mohler, E. J., Antwi-Boasiako, S., Murphy, N. P., et al. (2025) · JACC: Basic to Translational Science

Cardiovascular Effects of ExerciseCardiomyopathy and Myosin Studies

Cited by 5

A Paradigm Shift: Arrhythmogenic Cardiomyopathy Is an Inflammatory Disease

Ariyaratne, G. H. D. N., Villatore, A., Peretto, G., & Chelko, S. P. (2026) · Cells

Cardiovascular Effects of ExerciseCardiomyopathy and Myosin Studies

Cited by 2