Dubinsky, Marla

Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease

The International IBD Genetics Consortium (IIBDGC), Jostins, L., Ripke, S., Weersma, R. K., Duerr, R. H., McGovern, D. P., Hui, K. Y., Lee, J. C., Philip Schumm, L., Sharma, Y., et al. (2012) · Nature

Inflammatory Bowel DiseaseGenetic Associations and Epidemiology

Cited by 4,722

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

Franke, A., McGovern, D. P. B., Barrett, J. C., Wang, K., Radford-Smith, G. L., Ahmad, T., Lees, C. W., Balschun, T., Lee, J., Roberts, R., et al. (2010) · Nature Genetics

Inflammatory Bowel DiseaseGenetic Associations and Epidemiology

Cited by 2,520

Interactions between commensal fungi and the C-type lectin receptor Dectin-1 influence colitis

Iliev, I. D., Funari, V. A., Taylor, K. D., Nguyen, Q., Reyes, C. N., Strom, S. P., Brown, J., Becker, C. A., Fleshner, P. R., Dubinsky, M., et al. (2012) · Science

Gut microbiota and healthInflammatory Bowel Disease

Cited by 1,073

Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease

National Institute of Diabetes and Digestive Kidney Diseases Inflammatory Bowel Disease Genetics Consortium (NIDDK IBDGC), Rivas, M. A., United Kingdom Inflammatory Bowel Disease Genetics Consortium, International Inflammatory Bowel Disease Genetics Consortium, Beaudoin, M., Gardet, A., Stevens, C., Sharma, Y., Zhang, C. K., Boucher, G., et al. (2011) · Nature Genetics

Inflammatory Bowel DiseaseGenetic Associations and Epidemiology

Cited by 771

Microbiotas from Humans with Inflammatory Bowel Disease Alter the Balance of Gut Th17 and RORγt+ Regulatory T Cells and Exacerbate Colitis in Mice

Britton, G. J., Contijoch, E. J., Mogno, I., Vennaro, O. H., Llewellyn, S. R., Ng, R., Li, Z., Mortha, A., Merad, M., Das, A., et al. (2019) · Immunity

Inflammatory Bowel DiseaseGut microbiota and health

Cited by 549

Anti–Tumor Necrosis Factor Therapy and Incidence of Parkinson Disease Among Patients With Inflammatory Bowel Disease

Peter, I., Dubinsky, M., Bressman, S., Park, A., Lu, C., Chen, N., & Wang, A. (2018) · JAMA Neurology

Inflammatory Bowel DiseaseParkinson's Disease Mechanisms and Treatments

Cited by 386

Diverse Genome-wide Association Studies Associate the IL12/IL23 Pathway with Crohn Disease

Wang, K., Zhang, H., Kugathasan, S., Annese, V., Bradfield, J. P., Russell, R. K., Sleiman, P. M. A., Imielinski, M., Glessner, J., Hou, C., et al. (2009) · The American Journal of Human Genetics

Inflammatory Bowel DiseaseGenetic Associations and Epidemiology

Cited by 291

Fecal IgA Levels Are Determined by Strain-Level Differences in Bacteroides ovatus and Are Modifiable by Gut Microbiota Manipulation

Yang, C., Mogno, I., Contijoch, E. J., Borgerding, J. N., Aggarwala, V., Li, Z., Siu, S., Grasset, E. K., Helmus, D. S., Dubinsky, M. C., et al. (2020) · Cell Host & Microbe

Gut microbiota and healthProbiotics and Fermented Foods

Cited by 221

Infants born to mothers with IBD present with altered gut microbiome that transfers abnormalities of the adaptive immune system to germ-free mice

Torres, J., Hu, J., Seki, A., Eisele, C., Nair, N., Huang, R., Tarassishin, L., Jharap, B., Cote-Daigneault, J., Mao, Q., et al. (2020) · Gut

Gut microbiota and healthInflammatory Bowel Disease

Cited by 218

Transcriptional risk scores link GWAS to eQTLs and predict complications in Crohn's disease

Marigorta, U. M., Denson, L. A., Hyams, J. S., Mondal, K., Prince, J., Walters, T. D., Griffiths, A., Noe, J. D., Crandall, W. V., Rosh, J. R., et al. (2017) · Nature Genetics

Inflammatory Bowel DiseaseGenetic Associations and Epidemiology

Cited by 166

An international consensus to standardize integration of histopathology in ulcerative colitis clinical trials

Ma, C., Sedano, R., Almradi, A., Vande Casteele, N., Parker, C. E., Guizzetti, L., Schaeffer, D. F., Riddell, R. H., Pai, R. K., Battat, R., et al. (2021) · Gastroenterology

Inflammatory Bowel DiseaseMicroscopic Colitis

Cited by 105

High levels of psychological resilience associated with less disease activity, better quality of life, and fewer surgeries in inflammatory bowel disease

Sehgal, P., Ungaro, R. C., Foltz, C., Iacoviello, B., Dubinsky, M. C., & Keefer, L. (2021) · Inflammatory Bowel Diseases

Inflammatory Bowel DiseaseResilience and Mental Health

Cited by 82

Resilience-based integrated IBD care is associated with reductions in health care use and opioids

Keefer, L., Gorbenko, K., Siganporia, T., Manning, L., Tse, S., Biello, A., Ungaro, R., Cohen, L. J., Cohen, B. L., & Dubinsky, M. C. (2022) · Clinical Gastroenterology and Hepatology

Inflammatory Bowel DiseaseResilience and Mental Health

Cited by 49

High levels of psychological resilience are associated with decreased anxiety in inflammatory bowel disease

Philippou, A., Sehgal, P., Ungaro, R. C., Wang, K., Bagiella, E., Dubinsky, M. C., & Keefer, L. (2022) · Inflammatory Bowel Diseases

Resilience and Mental HealthInflammatory Bowel Disease

Cited by 43