Kauffman, Kevin J.

Delivery technologies for genome editing

Yin, H., Kauffman, K. J., & Anderson, D. G. (2017) · Nature Reviews Drug Discovery

CRISPR and Genetic EngineeringRNA Interference and Gene Delivery

Cited by 597

Structure-guided chemical modification of guide RNA enables potent non-viral in vivo genome editing

Yin, H., Song, C.-Q., Suresh, S., Wu, Q., Walsh, S., Rhym, L. H., Mintzer, E., Bolukbasi, M. F., Zhu, L. J., Kauffman, K., et al. (2017) · Nature Biotechnology

CRISPR and Genetic EngineeringRNA Interference and Gene Delivery

Cited by 499

Barcoded nanoparticles for high throughput in vivo discovery of targeted therapeutics

Dahlman, J. E., Kauffman, K. J., Xing, Y., Shaw, T. E., Mir, F. F., Dlott, C. C., Langer, R., Anderson, D. G., & Wang, E. T. (2017) · Proceedings of the National Academy of Sciences

RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery

Cited by 335

Optimization of a degradable polymer–lipid nanoparticle for potent systemic delivery of mRNA to the lung endothelium and immune cells

Kaczmarek, J. C., Kauffman, K. J., Fenton, O. S., Sadtler, K., Patel, A. K., Heartlein, M. W., DeRosa, F., & Anderson, D. G. (2018) · Nano Letters

RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery

Cited by 218

Therapeutic efficacy in a hemophilia B model using a biosynthetic mRNA liver depot system

DeRosa, F., Guild, B., Karve, S., Smith, L., Love, K., Dorkin, J. R., Kauffman, K. J., Zhang, J., Yahalom, B., Anderson, D. G., et al. (2016) · Gene Therapy

RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery

Cited by 159

Polymer–Lipid Nanoparticles for Systemic Delivery of mRNA to the Lungs

Kaczmarek, J. C., Patel, A. K., Kauffman, K. J., Fenton, O. S., Webber, M. J., Heartlein, M. W., DeRosa, F., & Anderson, D. G. (2016) · Angewandte Chemie

RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery

Cited by 60