Brack, Andrew S.

Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA

Warren, L., Manos, P. D., Ahfeldt, T., Loh, Y.-H., Li, H., Lau, F., Ebina, W., Mandal, P. K., Smith, Z. D., Meissner, A., et al. (2010) · Cell Stem Cell

Pluripotent Stem Cells ResearchCRISPR and Genetic Engineering

Cited by 2,662

Increased Wnt signaling during aging alters muscle stem cell fate and increases fibrosis

Brack, A. S., Conboy, M. J., Roy, S., Lee, M., Kuo, C. J., Keller, C., & Rando, T. A. (2007) · Science

Muscle Physiology and DisordersWnt/β-catenin signaling in development and cancer

Cited by 1,564

The aged niche disrupts muscle stem cell quiescence

Chakkalakal, J. V., Jones, K. M., Basson, M. A., & Brack, A. S. (2012) · Nature

Muscle Physiology and DisordersMesenchymal stem cell research

Cited by 851

A Temporal Switch from Notch to Wnt Signaling in Muscle Stem Cells Is Necessary for Normal Adult Myogenesis

Brack, A. S., Conboy, I. M., Conboy, M. J., Shen, J., & Rando, T. A. (2008) · Cell Stem Cell

Muscle Physiology and DisordersDevelopmental Biology and Gene Regulation

Cited by 682

GDF11 increases with age and inhibits skeletal muscle regeneration

Egerman, M. A., Cadena, S. M., Gilbert, J. A., Meyer, A., Nelson, H. N., Swalley, S. E., Mallozzi, C., Jacobi, C., Jennings, L. L., Clay, I., et al. (2015) · Cell Metabolism

Muscle Physiology and DisordersTGF-β signaling in diseases

Cited by 527

Sprouty1 regulates reversible quiescence of a self-renewing adult muscle stem cell pool during regeneration

Shea, K. L., Xiang, W., LaPorta, V. S., Licht, J. D., Keller, C., Basson, M. A., & Brack, A. S. (2010) · Cell stem cell

Muscle Physiology and DisordersCongenital heart defects research

Cited by 351

Intrinsic Changes and Extrinsic Influences of Myogenic Stem Cell Function During Aging

Brack, A. S., & Rando, T. A. (2007) · Stem Cell Reviews

Muscle Physiology and DisordersMesenchymal stem cell research

Cited by 238

Wnt4 from the Niche Controls the Mechano-Properties and Quiescent State of Muscle Stem Cells

Eliazer, S., Muncie, J. M., Christensen, J., Sun, X., D’Urso, R. S., Weaver, V. M., & Brack, A. S. (2019) · Cell Stem Cell

Muscle Physiology and DisordersHippo pathway signaling and YAP/TAZ

Cited by 171

The ins and outs of muscle stem cell aging

Brack, A. S., & Muñoz-Cánoves, P. (2015) · Skeletal Muscle

Muscle Physiology and DisordersMesenchymal stem cell research

Cited by 166

Early forming label-retaining muscle stem cells require p27kip1 for maintenance of the primitive state

Chakkalakal, J. V., Christensen, J., Xiang, W., Tierney, M. T., Boscolo, F. S., Sacco, A., & Brack, A. S. (2014) · Development

Muscle Physiology and DisordersDevelopmental Biology and Gene Regulation

Cited by 148

Aging induces aberrant state transition kinetics in murine muscle stem cells

Kimmel, J. C., Hwang, A. B., Scaramozza, A., Marshall, W. F., & Brack, A. S. (2020) · Development

Muscle Physiology and DisordersSingle-cell and spatial transcriptomics

Cited by 95

Lineage Tracing Reveals a Subset of Reserve Muscle Stem Cells Capable of Clonal Expansion under Stress

Scaramozza, A., Park, D., Kollu, S., Beerman, I., Sun, X., Rossi, D. J., Lin, C. P., Scadden, D. T., Crist, C., & Brack, A. S. (2019) · Cell Stem Cell

Muscle Physiology and DisordersMesenchymal stem cell research

Cited by 93

Inferring cell state by quantitative motility analysis reveals a dynamic state system and broken detailed balance

Kimmel, J. C., Chang, A. Y., Brack, A. S., & Marshall, W. F. (2018) · PLoS Computational Biology

Gene Regulatory Network AnalysisCell Image Analysis Techniques

Cited by 54