Kanemaki, Masato T.

An auxin-based degron system for the rapid depletion of proteins in nonplant cells

Nishimura, K., Fukagawa, T., Takisawa, H., Kakimoto, T., & Kanemaki, M. (2009) · Nature Methods

Ubiquitin and proteasome pathwaysProtein Degradation and Inhibitors

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Exosomes maintain cellular homeostasis by excreting harmful DNA from cells

Takahashi, A., Okada, R., Nagao, K., Kawamata, Y., Hanyu, A., Yoshimoto, S., Takasugi, M., Watanabe, S., Kanemaki, M. T., Obuse, C., et al. (2017) · Nature Communications

Extracellular vesicles in diseaseCellular transport and secretion

Cited by 761

Rapid protein depletion in human cells by auxin-inducible degron tagging with short homology donors

Natsume, T., Kiyomitsu, T., Saga, Y., & Kanemaki, M. T. (2016) · Cell Reports

CRISPR and Genetic EngineeringProtein Degradation and Inhibitors

Cited by 673

The Elg1 replication factor C-like complex functions in PCNA unloading during DNA replication

Kubota, T., Nishimura, K., Kanemaki, M. T., & Donaldson, A. D. (2013) · Molecular Cell

DNA Repair MechanismsFungal and yeast genetics research

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In silico protein interaction screening uncovers DONSON’s role in replication initiation

Lim, Y., Tamayo-Orrego, L., Schmid, E., Tarnauskaite, Z., Kochenova, O. V., Gruar, R., Muramatsu, S., Lynch, L., Schlie, A. V., Carroll, P. L., et al. (2023) · Science

DNA Repair MechanismsGenomics and Chromatin Dynamics

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RNaseH2A downregulation drives inflammatory gene expression via genomic DNA fragmentation in senescent and cancer cells

Sugawara, S., Okada, R., Loo, T. M., Tanaka, H., Miyata, K., Chiba, M., Kawasaki, H., Katoh, K., Kaji, S., Maezawa, Y., et al. (2022) · Communications Biology

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

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DNA methylation protects cancer cells against senescence

Chen, X., Yamaguchi, K., Rodgers, B., Goehrig, D., Vindrieux, D., Lahaye, X., Nolot, M., Ferry, L., Martin, N., Dubus, P., et al. (2024) · Nature Communications

Telomeres, Telomerase, and SenescenceEpigenetics and DNA Methylation

Cited by 17

DNA methylation protects cancer cells against senescence

Chen, X., Yamaguchi, K., Rodgers, B., Goehrig, D., Vindrieux, D., Lahaye, X., Nolot, M., Ferry, L., Lanciano, S., Martin, N., et al. (2025) · Nature Communications

Telomeres, Telomerase, and SenescenceEpigenetics and DNA Methylation

Cited by 17

The human RIF1-Long isoform interacts with BRCA1 to promote recombinational fork repair under DNA replication stress

Dong, Q., Day, M., Saito, Y., Parker, E., Watts, L. P., Kanemaki, M. T., Oliver, A. W., Pearl, L. H., Hiraga, S.-I., & Donaldson, A. D. (2025) · Nature Communications

DNA Repair MechanismsBRCA gene mutations in cancer

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