Gascoigne, Karen E.

Cancer Cells Display Profound Intra- and Interline Variation following Prolonged Exposure to Antimitotic Drugs

Gascoigne, K. E., & Taylor, S. S. (2008) · Cancer Cell

Microtubule and mitosis dynamicsCell death mechanisms and regulation

Cited by 832

Enhancer Activity Requires CBP/P300 Bromodomain-Dependent Histone H3K27 Acetylation

Raisner, R., Kharbanda, S., Jin, L., Jeng, E., Chan, E., Merchant, M., Haverty, P. M., Bainer, R., Cheung, T., Arnott, D., et al. (2018) · Cell Reports

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 375

Antibody Conjugation of a Chimeric BET Degrader Enables in vivo Activity

Pillow, T. H., Adhikari, P., Blake, R. A., Chen, J., Del Rosario, G., Deshmukh, G., Figueroa, I., Gascoigne, K. E., Kamath, A. V., Kaufman, S., et al. (2020) · ChemMedChem

Protein Degradation and InhibitorsChemical Synthesis and Analysis

Cited by 216

Therapeutic Targeting of the CBP/p300 Bromodomain Blocks the Growth of Castration-Resistant Prostate Cancer

Jin, L., Garcia, J., Chan, E., de la Cruz, C., Segal, E., Merchant, M., Kharbanda, S., Raisner, R., Haverty, P. M., Modrusan, Z., et al. (2017) · Cancer Research

Prostate Cancer Treatment and ResearchProtein Degradation and Inhibitors

Cited by 153

Antibody-Mediated Delivery of Chimeric BRD4 Degraders. Part 1: Exploration of Antibody Linker, Payload Loading, and Payload Molecular Properties

Dragovich, P. S., Pillow, T. H., Blake, R. A., Sadowsky, J. D., Adaligil, E., Adhikari, P., Bhakta, S., Blaquiere, N., Chen, J., dela Cruz-Chuh, J., et al. (2021) · Journal of Medicinal Chemistry

Protein Degradation and InhibitorsMonoclonal and Polyclonal Antibodies Research

Cited by 152

Induced dicentric chromosome formation promotes genomic rearrangements and tumorigenesis

Gascoigne, K. E., & Cheeseman, I. M. (2013) · Chromosome Research

Genomic variations and chromosomal abnormalitiesMicrotubule and mitosis dynamics

Cited by 65