Wree, Alexander

NLRP3 inflammasome blockade reduces liver inflammation and fibrosis in experimental NASH in mice

Mridha, A. R., Wree, A., Robertson, A. A. B., Yeh, M. M., Johnson, C. D., Van Rooyen, D. M., Haczeyni, F., Teoh, N. C.-H., Savard, C., Ioannou, G. N., et al. (2017) · Journal of Hepatology

Liver Disease Diagnosis and TreatmentInflammasome and immune disorders

Cited by 1,110

NLRP3 inflammasome activation results in hepatocyte pyroptosis, liver inflammation, and fibrosis in mice

Wree, A., Eguchi, A., McGeough, M. D., Pena, C. A., Johnson, C. D., Canbay, A., Hoffman, H. M., & Feldstein, A. E. (2014) · Hepatology

Inflammasome and immune disordersDrug-Induced Hepatotoxicity and Protection

Cited by 945

NLRP3 inflammasome activation is required for fibrosis development in NAFLD

Wree, A., McGeough, M. D., Peña, C. A., Schlattjan, M., Li, H., Inzaugarat, M. E., Messer, K., Canbay, A., Hoffman, H. M., & Feldstein, A. E. (2014) · Journal of Molecular Medicine

Liver Disease Diagnosis and TreatmentInflammasome and immune disorders

Cited by 486

NLRP3 inflammasome driven liver injury and fibrosis: roles of IL-17 and TNF in mice

Wree, A., McGeough, M. D., Inzaugarat, M. E., Eguchi, A., Schuster, S., Johnson, C. D., Peña, C. A., Geisler, L. J., Papouchado, B. G., Hoffman, H. M., et al. (2018) · Hepatology

Inflammasome and immune disordersLiver physiology and pathology

Cited by 266

Caspase 3 Inactivation Protects Against Hepatic Cell Death and Ameliorates Fibrogenesis in a Diet-Induced NASH Model

Thapaliya, S., Wree, A., Povero, D., Inzaugarat, M. E., Berk, M., Dixon, L., Papouchado, B. G., & Feldstein, A. E. (2014) · Digestive Diseases and Sciences

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

Cited by 162

NLR Family Pyrin Domain-Containing 3 Inflammasome Activation in Hepatic Stellate Cells Induces Liver Fibrosis in Mice

Inzaugarat, M. E., Johnson, C. D., Holtmann, T. M., McGeough, M. D., Trautwein, C., Papouchado, B. G., Schwabe, R., Hoffman, H. M., Wree, A., & Feldstein, A. E. (2019) · Hepatology

Liver physiology and pathologyInflammasome and immune disorders

Cited by 148

The NLRP3 inflammasome in alcoholic and nonalcoholic steatohepatitis

Knorr, J., Wree, A., Tacke, F., & Feldstein, A. E. (2020) · Seminars in Liver Disease

Inflammasome and immune disordersLiver Disease Diagnosis and Treatment

Cited by 99

Beneficial effects of mineralocorticoid receptor blockade in experimental non‐alcoholic steatohepatitis

Pizarro, M., Solís, N., Quintero, P., Barrera, F., Cabrera, D., Rojas‐de Santiago, P., Arab, J. P., Padilla, O., Roa, J. C., Moshage, H., et al. (2015) · Liver International

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

Cited by 66

Cell-specific Deletion of NLRP3 Inflammasome Identifies Myeloid Cells as Key Drivers of Liver Inflammation and Fibrosis in Murine Steatohepatitis

Kaufmann, B., Kui, L., Reca, A., Leszczynska, A., Kim, A. D., Booshehri, L. M., Wree, A., Friess, H., Hartmann, D., Broderick, L., et al. (2022) · Cellular and Molecular Gastroenterology and Hepatology

Liver Disease Diagnosis and TreatmentInflammasome and immune disorders

Cited by 51