Klein, Samuel

Obesity dysregulates fasting-induced changes in glucagon secretion

Stern, J. H., Smith, G. I., Chen, S., Unger, R. H., Klein, S., & Scherer, P. E. (2019) · Journal of Endocrinology

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 84

Whole-body lipolysis and triglyceride-fatty acid cycling in cachectic patients with esophageal cancer.

Klein, S., & Wolfe, R. R. (1990) · Journal of Clinical Investigation

Nutrition and Health in AgingClinical Nutrition and Gastroenterology

Cited by 82

Influence of adiposity, insulin resistance, and intrahepatic triglyceride content on insulin kinetics

Smith, G. I., Polidori, D. C., Yoshino, M., Kearney, M. L., Patterson, B. W., Mittendorfer, B., & Klein, S. (2020) · Journal of Clinical Investigation

Liver Disease Diagnosis and TreatmentPancreatic function and diabetes

Cited by 78

Licogliflozin for nonalcoholic steatohepatitis: a randomized, double-blind, placebo-controlled, phase 2a study

Harrison, S. A., Manghi, F. P., Smith, W. B., Alpenidze, D., Aizenberg, D., Klarenbeek, N., Chen, C.-Y., Zuckerman, E., Ravussin, E., Charatcharoenwitthaya, P., et al. (2022) · Nature Medicine

Liver Disease Diagnosis and TreatmentDiabetes Treatment and Management

Cited by 75

Diurnal Variation in Insulin Sensitivity of Glucose Metabolism Is Associated With Diurnal Variations in Whole-Body and Cellular Fatty Acid Metabolism in Metabolically Normal Women

Yoshino, J., Almeda-Valdes, P., Patterson, B. W., Okunade, A. L., Imai, S.-I., Mittendorfer, B., & Klein, S. (2014) · The Journal of Clinical Endocrinology & Metabolism

Circadian rhythm and melatoninAdipose Tissue and Metabolism

Cited by 75

The Extracellular Matrix Protein MAGP1 Supports Thermogenesis and Protects Against Obesity and Diabetes Through Regulation of TGF-β

Craft, C. S., Pietka, T. A., Schappe, T., Coleman, T., Combs, M. D., Klein, S., Abumrad, N. A., & Mecham, R. P. (2014) · Diabetes

Adipose Tissue and MetabolismAdipokines, Inflammation, and Metabolic Diseases

Cited by 73

Metabolic subtypes of patients with NAFLD exhibit distinctive cardiovascular risk profiles

Martínez‐Arranz, I., Bruzzone, C., Noureddin, M., Gil‐Redondo, R., Mincholé, I., Bizkarguenaga, M., Arretxe, E., Iruarrizaga‐Lejarreta, M., Fernández‐Ramos, D., Lopitz‐Otsoa, F., et al. (2022) · Hepatology

Liver Disease Diagnosis and TreatmentDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 65

Generalized lipodystrophy: In vivo evidence for hypermetabolism and insulin-resistant lipid, glucose, and amino acid kinetics

Klein, S., Jahoor, F., Wolfe, R. R., & Stuart, C. A. (1992) · Metabolism

Lipid metabolism and disordersDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 41

Steatosis drives monocyte-derived macrophage accumulation in human metabolic dysfunction-associated fatty liver disease

Chan, M. M., Daemen, S., Beals, J. W., Terekhova, M., Yang, B. Q., Fu, C. F., He, L., Park, A. C., Smith, G. I., Razani, B., et al. (2023) · JHEP Reports

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

Cited by 29

Importance of Adipose Tissue NAD+ Biology in Regulating Metabolic Flexibility

Franczyk, M. P., Qi, N., Stromsdorfer, K. L., Li, C., Yamaguchi, S., Itoh, H., Yoshino, M., Sasaki, Y., Brookheart, R. T., Finck, B. N., et al. (2021) · Endocrinology

Sirtuins and Resveratrol in MedicineAdipose Tissue and Metabolism

Cited by 23

Fundamentals of Cardipmetabolic Risk Factor Reduction: Achieving and Maintaining Weight Loss with Pharmacotherapy or Bariatric Surgery

Fabbrini, E., & Klein, S. (2008) · Clinical Cornerstone

Pharmacology and Obesity TreatmentBariatric Surgery and Outcomes

Cited by 9

N-acetylaspartate from fat cells regulates postprandial body temperature

Felix, J. B., Saha, P. K., de Groot, E. L., Tan, L., Sharp, R., Anaya, E. S., Li, Y., Quang, H., Saidi, N., Abushamat, L., et al. (2025) · Nature Metabolism

Adipose Tissue and MetabolismAdipokines, Inflammation, and Metabolic Diseases

Cited by 6