Ponting, Chris P.

Initial sequencing and analysis of the human genome

International Human Genome Sequencing Consortium, Whitehead Institute for Biomedical Research, C. F. G. R., Lander, E. S., Linton, L. M., Birren, B., Nusbaum, C., Zody, M. C., Baldwin, J., Devon, K., Dewar, K., et al. (2001) · Nature

Genomics and Phylogenetic StudiesGenetic Associations and Epidemiology

Cited by 24,216

Regulation of chromatin structure by site-specific histone H3 methyltransferases

Rea, S., Eisenhaber, F., O'Carroll, D., Strahl, B. D., Sun, Z.-W., Schmid, M., Opravil, S., Mechtler, K., Ponting, C. P., Allis, C. D., et al. (2000) · Nature

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 2,845

Genome sequence, comparative analysis and haplotype structure of the domestic dog

members, B. S. P., Lindblad-Toh, K., Wade, C. M., Mikkelsen, T. S., Karlsson, E. K., Jaffe, D. B., Kamal, M., Clamp, M., Chang, J. L., Kulbokas, E. J., et al. (2005) · Nature

Human-Animal Interaction StudiesGenetic and phenotypic traits in livestock

Cited by 2,568

Functional impact of global rare copy number variation in autism spectrum disorders

Pinto, D., Pagnamenta, A. T., Klei, L., Anney, R., Merico, D., Regan, R., Conroy, J., Magalhaes, T. R., Correia, C., Abrahams, B. S., et al. (2010) · Nature

Autism Spectrum Disorder ResearchGenomic variations and chromosomal abnormalities

Cited by 2,013

Resolving the fibrotic niche of human liver cirrhosis at single-cell level

Ramachandran, P., Dobie, R., Wilson-Kanamori, J. R., Dora, E. F., Henderson, B. E. P., Luu, N. T., Portman, J. R., Matchett, K. P., Brice, M., Marwick, J. A., et al. (2019) · Nature

Liver physiology and pathologyLiver Diseases and Immunity

Cited by 1,784

Mouse genomic variation and its effect on phenotypes and gene regulation.

Keane, T. M., Goodstadt, L., Danecek, P., White, M. A., Wong, K., Yalcin, B., Heger, A., Agam, A., Slater, G., Goodson, M., et al. (2011) · Nature

Genetic Mapping and Diversity in Plants and AnimalsGenetic and phenotypic traits in livestock

Cited by 1,580

Identification of region-specific astrocyte subtypes at single cell resolution

Batiuk, M. Y., Martirosyan, A., Wahis, J., de Vin, F., Marneffe, C., Kusserow, C., Koeppen, J., Viana, J. F., Oliveira, J. F., Voet, T., et al. (2020) · Nature Communications

Single-cell and spatial transcriptomicsNeuroscience and Neuropharmacology Research

Cited by 805

G&T-seq: parallel sequencing of single-cell genomes and transcriptomes

Macaulay, I. C., Haerty, W., Kumar, P., Li, Y. I., Hu, T. X., Teng, M. J., Goolam, M., Saurat, N., Coupland, P., Shirley, L. M., et al. (2015) · Nature Methods

Single-cell and spatial transcriptomicsGenomics and Phylogenetic Studies

Cited by 750

Parallel single-cell sequencing links transcriptional and epigenetic heterogeneity

Angermueller, C., Clark, S. J., Lee, H. J., Macaulay, I. C., Teng, M. J., Hu, T. X., Krueger, F., Smallwood, S. A., Ponting, C. P., Voet, T., et al. (2016) · Nature Methods

Epigenetics and DNA MethylationSingle-cell and spatial transcriptomics

Cited by 717

Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequences

Broad Institute Genome Sequencing Platform, Mikkelsen, T. S., Broad Institute Whole Genome Assembly Team, Wakefield, M. J., Aken, B., Amemiya, C. T., Chang, J. L., Duke, S., Garber, M., Gentles, A. J., et al. (2007) · Nature

Chromosomal and Genetic VariationsGenomics and Phylogenetic Studies

Cited by 711

The bonobo genome compared with the chimpanzee and human genomes

Prüfer, K., Munch, K., Hellmann, I., Akagi, K., Miller, J. R., Walenz, B., Koren, S., Sutton, G., Kodira, C., Winer, R., et al. (2012) · Nature

Genomics and Phylogenetic StudiesPrimate Behavior and Ecology

Cited by 579

Combined Single-Cell Functional and Gene Expression Analysis Resolves Heterogeneity within Stem Cell Populations

Wilson, N. K., Kent, D. G., Buettner, F., Shehata, M., Macaulay, I. C., Calero-Nieto, F. J., Sánchez Castillo, M., Oedekoven, C. A., Diamanti, E., Schulte, R., et al. (2015) · Cell Stem Cell

Hematopoietic Stem Cell TransplantationSingle-cell and spatial transcriptomics

Cited by 466

Single-cell multiomics: multiple measurements from single cells

Macaulay, I. C., Ponting, C. P., & Voet, T. (2017) · Trends in Genetics

Single-cell and spatial transcriptomicsGenomics and Phylogenetic Studies

Cited by 451

Single-cell transcriptomics uncovers zonation of function in the mesenchyme during liver fibrosis

Dobie, R., Wilson-Kanamori, J. R., Henderson, B. E. P., Smith, J. R., Matchett, K. P., Portman, J. R., Wallenborg, K., Picelli, S., Zagorska, A., Pendem, S. V., et al. (2019) · Cell Reports

Liver physiology and pathologyLiver Disease Diagnosis and Treatment

Cited by 420

START: a lipid-binding domain in StAR, HD-ZIP and signalling proteins

Ponting, C. P., & Aravind, L. (1999) · Trends in Biochemical Sciences

Lipid Membrane Structure and BehaviorProtein Kinase Regulation and GTPase Signaling

Cited by 398

GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19

Pairo-Castineira, E., Rawlik, K., Bretherick, A. D., Qi, T., Wu, Y., Nassiri, I., McConkey, G. A., Zechner, M., Klaric, L., Griffiths, F., et al. (2023) · Nature

Genetic Associations and EpidemiologyCOVID-19 Clinical Research Studies

Cited by 225

TRAM, LAG1 and CLN8: members of a novel family of lipid-sensing domains?

Winter, E., & Ponting, C. P. (2002) · Trends in Biochemical Sciences

Sphingolipid Metabolism and SignalingLysosomal Storage Disorders Research

Cited by 181

Phylogenetic Reconstruction of Orthology, Paralogy, and Conserved Synteny for Dog and Human

Goodstadt, L., & Ponting, C. P. (2006) · PLoS Computational Biology

Genomics and Phylogenetic StudiesChromosomal and Genetic Variations

Cited by 154

Death of PRDM9 coincides with stabilization of the recombination landscape in the dog genome

Axelsson, E., Webster, M. T., Ratnakumar, A., The LUPA Consortium, Ponting, C. P., & Lindblad-Toh, K. (2012) · Genome Research

Chromosomal and Genetic VariationsGenetic Mapping and Diversity in Plants and Animals

Cited by 142

Identification of the MMS22L-TONSL Complex that Promotes Homologous Recombination

Duro, E., Lundin, C., Ask, K., Sanchez-Pulido, L., MacArtney, T. J., Toth, R., Ponting, C. P., Groth, A., Helleday, T., & Rouse, J. (2010) · Molecular Cell

DNA Repair MechanismsFungal and yeast genetics research

Cited by 125

Genome-Wide analysis of human long noncoding RNAs: a provocative review

Ponting, C. P., & Haerty, W. (2022) · Annual Review of Genomics and Human Genetics

Cancer-related molecular mechanisms researchChromosomal and Genetic Variations

Cited by 115

An analysis of the gene complement of a marsupial,Monodelphis domestica: Evolution of lineage-specific genes and giant chromosomes

Goodstadt, L., Heger, A., Webber, C., & Ponting, C. P. (2007) · Genome Research

Chromosomal and Genetic VariationsGenomics and Phylogenetic Studies

Cited by 67

Microglia recapitulate a hematopoietic master regulator network in the aging human frontal cortex

Wehrspaun, C. C., Haerty, W., & Ponting, C. P. (2015) · Neurobiology of Aging

Neuroinflammation and Neurodegeneration MechanismsSingle-cell and spatial transcriptomics

Cited by 64

TM6SF2 and MAC30, new enzyme homologs in sterol metabolism and common metabolic disease

Sanchez-Pulido, L., & Ponting, C. P. (2014) · Frontiers in Genetics

Cholesterol and Lipid MetabolismCancer, Lipids, and Metabolism

Cited by 63