Lu, Tao

Gene regulation and DNA damage in the ageing human brain

Lu, T., Pan, Y., Kao, S.-Y., Li, C., Kohane, I., Chan, J., & Yankner, B. A. (2004) · Nature

Genetics, Aging, and Longevity in Model OrganismsDNA Repair Mechanisms

Cited by 1,874

Neural mechanisms of ageing and cognitive decline

Bishop, N. A., Lu, T., & Yankner, B. A. (2010) · Nature

Genetics, Aging, and Longevity in Model OrganismsDementia and Cognitive Impairment Research

Cited by 1,323

The DNA damage response induces inflammation and senescence by inhibiting autophagy of GATA4.

Kang, C., Xu, Q., Martin, T. D., Li, M. Z., Demaria, M., Aron, L., Lu, T., Yankner, B. A., Campisi, J., & Elledge, S. J. (2015) · Science

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 982

Genome-wide analysis reveals mechanisms modulating autophagy in normal brain aging and in Alzheimer’s disease

Lipinski, M. M., Zheng, B., Lu, T., Yan, Z., Py, B. F., Ng, A., Xavier, R. J., Li, C., Yankner, B. A., Scherzer, C. R., et al. (2010) · Proceedings of the National Academy of Sciences

Autophagy in Disease and TherapyAlzheimer's disease research and treatments

Cited by 680

The Aging Brain

Yankner, B. A., Lu, T., & Loerch, P. (2008) · Annual Review of Pathology: Mechanisms of Disease

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 677

Regulation of intracellular accumulation of mutant Huntingtin by Beclin 1

Shibata, M., Lu, T., Furuya, T., Degterev, A., Mizushima, N., Yoshimori, T., MacDonald, M., Yankner, B., & Yuan, J. (2006) · Journal of Biological Chemistry

Genetic Neurodegenerative DiseasesAutophagy in Disease and Therapy

Cited by 458

Evolution of the Aging Brain Transcriptome and Synaptic Regulation

Loerch, P. M., Lu, T., Dakin, K. A., Vann, J. M., Isaacs, A., Geula, C., Wang, J., Pan, Y., Gabuzda, D. H., Li, C., et al. (2008) · PLoS ONE

Genetics, Aging, and Longevity in Model OrganismsNeuroscience and Neuropharmacology Research

Cited by 334

Large eQTL meta-analysis reveals differing patterns between cerebral cortical and cerebellar brain regions

Sieberts, S. K., Perumal, T. M., Carrasquillo, M. M., Allen, M., Reddy, J. S., Hoffman, G. E., Dang, K. K., Calley, J., Ebert, P. J., Eddy, J., et al. (2020) · Scientific Data

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 318

REST and neural gene network dysregulation in iPSC models of Alzheimer’s disease

Meyer, K., Feldman, H. M., Lu, T., Drake, D., Lim, E. T., Ling, K.-H., Bishop, N. A., Pan, Y., Seo, J., Lin, Y.-T., et al. (2019) · Cell Reports

Alzheimer's disease research and treatmentsPluripotent Stem Cells Research

Cited by 216

Deep fusion learning facilitates anatomical therapeutic chemical recognition in drug repurposing and discovery

Wang, X., Liu, M., Zhang, Y., He, S., Qin, C., Li, Y., & Lu, T. (2021) · Briefings in Bioinformatics

Computational Drug Discovery MethodsBioinformatics and Genomic Networks

Cited by 16