Higashimori, Haruki

Neuronal Exosomal miRNA-dependent Translational Regulation of Astroglial Glutamate Transporter GLT1

Morel, L., Regan, M., Higashimori, H., Ng, S. K., Esau, C., Vidensky, S., Rothstein, J., & Yang, Y. (2013) · Journal of Biological Chemistry

Extracellular vesicles in diseaseNeuroscience and Neuropharmacology Research

Cited by 430

Exosome reporter mice reveal the involvement of exosomes in mediating neuron to astroglia communication in the CNS

Men, Y., Yelick, J., Jin, S., Tian, Y., Chiang, M. S. R., Higashimori, H., Brown, E., Jarvis, R., & Yang, Y. (2019) · Nature Communications

Extracellular vesicles in diseaseCellular transport and secretion

Cited by 357

Molecular and Functional Properties of Regional Astrocytes in the Adult Brain

Morel, L., Chiang, M. S. R., Higashimori, H., Shoneye, T., Iyer, L. K., Yelick, J., Tai, A., & Yang, Y. (2017) · The Journal of Neuroscience

Neuroscience and Neuropharmacology ResearchNeuroinflammation and Neurodegeneration Mechanisms

Cited by 243

Selective deletion of astroglial FMRP dysregulates glutamate transporter GLT1 and contributes to fragile X syndrome phenotypes in vivo.

Higashimori, H., Schin, C. S., Chiang, M. S. R., Morel, L., Shoneye, T. A., Nelson, D. L., & Yang, Y. (2016) · Journal of Neuroscience

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 105

Role of Kir4.1 channels in growth control of glia

Higashimori, H., & Sontheimer, H. (2007) · Glia

Ion channel regulation and functionIon Transport and Channel Regulation

Cited by 101

Abnormal Intracellular Calcium Signaling and SNARE-Dependent Exocytosis Contributes to SOD1G93A Astrocyte-Mediated Toxicity in Amyotrophic Lateral Sclerosis

Kawamata, H., Ng, S. K., Diaz, N., Burstein, S., Morel, L., Osgood, A., Sider, B., Higashimori, H., Haydon, P. G., Manfredi, G., et al. (2014) · The Journal of Neuroscience

Amyotrophic Lateral Sclerosis ResearchCellular transport and secretion

Cited by 97

Astroglial FMRP-dependent translational down-regulation of mGluR5 underlies glutamate transporter GLT1 dysregulation in the fragile X mouse.

Higashimori, H., Morel, L., Huth, J., Lindemann, L., Dulla, C., Taylor, A., Freeman, M., & Yang, Y. (2013) · Human Molecular Genetics

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 85

Intracortical astrocyte subpopulations defined by astrocyte reporter Mice in the adult brain

Morel, L., Men, Y., Chiang, M. S. R., Tian, Y., Jin, S., Yelick, J., Higashimori, H., & Yang, Y. (2019) · Glia

Neuroscience and Neuropharmacology ResearchNeuroinflammation and Neurodegeneration Mechanisms

Cited by 59

Functionally clustered mRNAs are distinctly enriched at cortical astroglial processes and are preferentially affected by FMRP deficiency.

Men, Y., Higashimori, H., Reynolds, K., Tu, L., Jarvis, R., & Yang, Y. (2022) · The Journal of Neuroscience

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 7